Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Christopher Aled Chamberlain"'
Autor:
Christopher Aled Chamberlain, Eric Paul Bennett, Anders Handrup Kverneland, Inge Marie Svane, Marco Donia, Özcan Met
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 417-428 (2022)
Adoptive T cell therapy (ACT) with expanded tumor-infiltrating lymphocytes (TIL) can induce durable responses in cancer patients from multiple histologies, with response rates of up to 50%. Antibodies blocking the engagement of the inhibitory recepto
Externí odkaz:
https://doaj.org/article/e7d0ab4e5744431699de187f51ed9968
Publikováno v:
Immuno, Vol 1, Iss 3, Pp 194-211 (2021)
The past decades of cancer immunotherapy research have provided profound evidence that the immune system is capable of inducing durable tumor regression. Although many commercialized anti-cancer immunotherapies are available to patients, these treatm
Externí odkaz:
https://doaj.org/article/5904b3b84e2742099dd61ed743b89f83
Autor:
Arianna Draghi, Christopher Aled Chamberlain, Shawez Khan, Krisztian Papp, Martin Lauss, Samuele Soraggi, Haja Dominike Radic, Mario Presti, Katja Harbst, Aishwarya Gokuldass, Anders Kverneland, Morten Nielsen, Marie Christine Wulff Westergaard, Mads Hald Andersen, Istvan Csabai, Göran Jönsson, Zoltan Szallasi, Inge Marie Svane, Marco Donia
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Detecting the entire repertoire of tumor-specific reactive tumor-infiltrating lymphocytes (TILs) is essential for investigating their immunological functions in the tumor microenvironment. Current in vitro assays identifying tumor-specific functional
Externí odkaz:
https://doaj.org/article/656d1c3e4153414e9f09ed73929cd351
Autor:
Marco Donia, Troels Holz Borch, Özcan Met, Julie Westerlin Kjeldsen, Morten Nielsen, Inge Marie Svane, Anders Handrup Kverneland, Christopher Aled Chamberlain, Sofie Kirial Mørk, Cathrine Lund Lorentzen, Lise Pyndt Jørgensen, Lene Buhl Riis, Christina Westmose Yde
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/f0af08021a4a4bf1a713d50b686b096c
Autor:
Aishwarya Gokuldass, Arianna Draghi, Krisztian Papp, Troels Holz Borch, Morten Nielsen, Marie Christine Wulff Westergaard, Rikke Andersen, Aimilia Schina, Kalijn Fredrike Bol, Christopher Aled Chamberlain, Mario Presti, Özcan Met, Katja Harbst, Martin Lauss, Samuele Soraggi, Istvan Csabai, Zoltán Szállási, Göran Jönsson, Inge Marie Svane, Marco Donia
Publikováno v:
Cancers, Vol 12, Iss 11, p 3344 (2020)
Background: Human intratumoral T cell infiltrates can be defined by quantitative or qualitative features, such as their ability to recognize autologous tumor antigens. In this study, we reproduced the tumor-T cell interactions of individual patients
Externí odkaz:
https://doaj.org/article/c12d497b7b014bddb32bbbf463d74d86
Autor:
Marco Donia, Inge Marie Svane, Michael Douglas Crowther, Zoltan Szallasi, John Wojcik, Christina Westmose Yde, Aimilia Schina, Christopher Aled Chamberlain, Arianna Draghi, Agnete Witness Præst Jensen, Zsofia Sztupinszki, Mario Presti, Morten Nielsen
Responses to immunotherapy can be very durable but acquired resistance leading to tumor progression often occurs. We investigated a patient with melanoma resistant to anti–programmed death 1 (anti–PD-1) who participated in the CA224-020 clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be2543f42e51875b4137f0e5ac21400
https://doi.org/10.1158/2326-6066.c.6550865
https://doi.org/10.1158/2326-6066.c.6550865
Autor:
Marco Donia, Inge Marie Svane, Michael Douglas Crowther, Zoltan Szallasi, John Wojcik, Christina Westmose Yde, Aimilia Schina, Christopher Aled Chamberlain, Arianna Draghi, Agnete Witness Præst Jensen, Zsofia Sztupinszki, Mario Presti, Morten Nielsen
Supplementary Figure from Coexisting Alterations of MHC Class I Antigen Presentation and IFNγ Signaling Mediate Acquired Resistance of Melanoma to Post–PD-1 Immunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cbdac981e7d2f5bc684d8383485f03a
https://doi.org/10.1158/2326-6066.22545140.v1
https://doi.org/10.1158/2326-6066.22545140.v1
Publikováno v:
Immuno, Vol 1, Iss 12, Pp 194-211 (2021)
Morgan Hulen, T, Chamberlain, C A, Svane, I M & Met, Ö 2021, ' ACT Up TIL Now: The Evolution of Tumor-Infiltrating Lymphocytes in Adoptive Cell Therapy for the Treatment of Solid Tumors ', Immuno, vol. 1, no. 3, pp. 194-211 . https://doi.org/10.3390/immuno1030012
Morgan Hulen, T, Chamberlain, C A, Svane, I M & Met, Ö 2021, ' ACT Up TIL Now: The Evolution of Tumor-Infiltrating Lymphocytes in Adoptive Cell Therapy for the Treatment of Solid Tumors ', Immuno, vol. 1, no. 3, pp. 194-211 . https://doi.org/10.3390/immuno1030012
The past decades of cancer immunotherapy research have provided profound evidence that the immune system is capable of inducing durable tumor regression. Although many commercialized anti-cancer immunotherapies are available to patients, these treatm
Autor:
Morten Nielsen, Mario Presti, Zsofia Sztupinszki, Agnete Witness Præst Jensen, Arianna Draghi, Christopher Aled Chamberlain, Aimilia Schina, Christina Westmose Yde, John Wojcik, Zoltan Szallasi, Michael Douglas Crowther, Inge Marie Svane, Marco Donia
Publikováno v:
Cancer immunology research. 10(10)
Responses to immunotherapy can be very durable but acquired resistance leading to tumor progression often occurs. We investigated a patient with melanoma resistant to anti–programmed death 1 (anti–PD-1) who participated in the CA224-020 clinical
Autor:
Yiyuan Niu, Hans H. Wandall, Ida Elisabeth Johansen, Morten Frödin, Christopher Aled Chamberlain, Eric P. Bennett, Özcan Met, Bent O. Petersen, Zhang Yang
Publikováno v:
Nucleic Acids Research
Bennett, E P, Petersen, B L, Johansen, I E, Niu, Y, Yang, Z, Chamberlain, C A, Met, Ö, Wandall, H H & Frödin, M 2020, ' INDEL detection, the 'Achilles heel' of precise genome editing : a survey of methods for accurate profiling of gene editing induced indels ', Nucleic Acids Research, vol. 48, no. 21, pp. 11958-11981 . https://doi.org/10.1093/nar/gkaa975
Bennett, E P, Petersen, B L, Johansen, I E, Niu, Y, Yang, Z, Chamberlain, C A, Met, Ö, Wandall, H H & Frödin, M 2020, ' INDEL detection, the 'Achilles heel' of precise genome editing : a survey of methods for accurate profiling of gene editing induced indels ', Nucleic Acids Research, vol. 48, no. 21, pp. 11958-11981 . https://doi.org/10.1093/nar/gkaa975
Advances in genome editing technologies have enabled manipulation of genomes at the single base level. These technologies are based on programmable nucleases (PNs) that include meganucleases, zinc-finger nucleases (ZFNs), transcription activator-like