Zobrazeno 1 - 10
of 848
pro vyhledávání: '"Christopher A. Ward"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Hyperthermia induced by phenethylamines, such as 3,4–methylenedioxymethamphetamine (MDMA), can lead to life-threatening complications and death. Activation of the sympathetic nervous system and subsequent release of norepinephrine and acti
Externí odkaz:
https://doaj.org/article/68406beb235d41799624f267e8d05ea3
Publikováno v:
eLife, Vol 12 (2024)
Central noradrenergic (NA) neurons are key constituents of the respiratory homeostatic network. NA dysfunction is implicated in several developmental respiratory disorders including Congenital Central Hyperventilation Syndrome (CCHS), Sudden Infant D
Externí odkaz:
https://doaj.org/article/7966347ab16345b0b3e90a1b1d8f1212
Autor:
Keith R. Brunt, Jun Wu, Zhilin Chen, Daniel Poeckel, Ryan A. Dercho, Luis G. Melo, Colin D. Funk, Christopher A. Ward, Ren-Ke Li
Publikováno v:
Cell Transplantation, Vol 21 (2012)
The aim of this study was to evaluate the overexpression of genes central to cell survival and angiogenesis to enhance the function of human late outgrowth endothelial progenitor cells (EPCs) and their utility for infarct recovery. Ischemic myocardia
Externí odkaz:
https://doaj.org/article/a5b934dcbe354639a0702f0eca7d5263
Autor:
Ondrej Suchanek, John R. Ferdinand, Zewen K. Tuong, Sathi Wijeyesinghe, Anita Chandra, Ann-Katrin Clauder, Larissa N. Almeida, Simon Clare, Katherine Harcourt, Christopher J. Ward, Rachael Bashford-Rogers, Trevor Lawley, Rudolf A. Manz, Klaus Okkenhaug, David Masopust, Menna R. Clatworthy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract B cells play a central role in humoral immunity but also have antibody-independent functions. Studies to date have focused on B cells in blood and secondary lymphoid organs but whether B cells reside in non-lymphoid organs (NLO) in homeostas
Externí odkaz:
https://doaj.org/article/c0d8e43c40604f7b822a7676214f0253
Autor:
Chang Seok Lee, Sung Yun Jung, Rachel Sue Zhen Yee, Nadia H. Agha, Jin Hong, Ting Chang, Lyle W. Babcock, Jorie D. Fleischman, Benjamin Clayton, Amy D. Hanna, Christopher S. Ward, Denise Lanza, Ayrea E. Hurley, Pumin Zhang, Xander H. T. Wehrens, William R. Lagor, George G. Rodney, Susan L. Hamilton
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-19 (2023)
Abstract Here we show that striated muscle preferentially expressed protein kinase α (Spegα) maintains cardiac function in hearts with Spegβ deficiency. Speg is required for stability of excitation-contraction coupling (ECC) complexes and interact
Externí odkaz:
https://doaj.org/article/7a8ed53a9dd64509bc4efd890aaae296
Autor:
Amal Aburahma, Emma L. Stewart, Srishti Rana, Ray Larsen, Christopher S. Ward, Jon E. Sprague
Publikováno v:
International Journal of Hyperthermia, Vol 40, Iss 1 (2023)
AbstractObjective To investigate the effect of bidirectional fecal microbial transplant (FMT) between male and female rats on methamphetamine (MA)-induced hyperthermia.Methods FMT was performed between male and female rats prior to MA (10 mg/kg, sc)
Externí odkaz:
https://doaj.org/article/7e8d44f3f3a24fa2b667e166757caae8
Autor:
Anicca D. Harriot, Tessa Altair Morris, Camilo Vanegas, Jacob Kallenbach, Kaylie Pinto, Humberto C. Joca, Marie-Jo Moutin, Guoli Shi, Jeanine A. Ursitti, Anna Grosberg, Christopher W. Ward
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Altered myofibrillar structure is a consequence of dystrophic pathology that impairs skeletal muscle contractile function and increases susceptibility to contraction injury. In murine Duchenne muscular dystrophy (mdx), myofibrillar alterations are ab
Externí odkaz:
https://doaj.org/article/a51700562a7c4ab8a3cb96c40aeb52a0
Autor:
Hugo Bibollet, Elton L. Nguyen, Daniel R. Miranda, Christopher W. Ward, Andrew A. Voss, Martin F. Schneider, Erick O. Hernández‐Ochoa
Publikováno v:
Physiological Reports, Vol 11, Iss 9, Pp n/a-n/a (2023)
Abstract In skeletal muscle, CaV1.1 serves as the voltage sensor for both excitation‐contraction coupling (ECC) and L‐type Ca2+ channel activation. We have recently adapted the technique of action potential (AP) voltage clamp (APVC) to monitor th
Externí odkaz:
https://doaj.org/article/936e352654cf477daee58c2bc9bd9210
Autor:
Justin G. Boyer, Jiuzhou Huo, Sarah Han, Julian R. Havens, Vikram Prasad, Brian L. Lin, David A. Kass, Taejeong Song, Sakthivel Sadayappan, Ramzi J. Khairallah, Christopher W. Ward, Jeffery D. Molkentin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Boyer et al. created genetic mouse models of muscular dystrophy in which satellite cells were selectively depleted. The depletion of satellite cells at select times was protective. Myofibers no longer had plasma membrane instability leading to tissue
Externí odkaz:
https://doaj.org/article/05d4e5eb19ab42dd9227ed224828f09d
Publikováno v:
Australian Journal of Grape and Wine Research, Vol 2023 (2023)
Background and Aims. Shiraz (Syrah) is a dark-skinned cultivar of the wine grape Vitis vinifera that forms the basis of some of the world’s most iconic wines. Worldwide, Shiraz is the fourth most planted grapevine cultivar; however, it represents t
Externí odkaz:
https://doaj.org/article/605422dc4dd44454a8119604d042327a