Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christopher A. Waddling"'
Publikováno v:
Archives of Biochemistry and Biophysics. 612:1-8
DosS is a sensor in Mycobacterium tuberculosis that differentially responds to O2, NO, and CO, as well as to changes in the redox state of the prosthetic heme iron atom. The ferrous protein and its Fe(II)-NO and Fe(II)-CO complexes undergo autophosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13df676dcf405b88954a9b1c6d91601f
https://doi.org/10.1016/j.abb.2016.10.005
https://doi.org/10.1016/j.abb.2016.10.005
Publikováno v:
Biochemistry
Biochemistry, vol 54, iss 46
Biochemistry, vol 54, iss 46
Mycobacterium tuberculosis (Mtb) and Mycobacterium smegmatis (Msmeg) can grow on cholesterol as the sole carbon source. In Mtb the utilization of cholesterol can be initiated by CYP125A1 or CYP142A1 and in Msmeg by the orthologous CYP125A3 and CYP142
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f75ce5aa0ae183743ea037723b6465ea
http://europepmc.org/articles/PMC4660985
http://europepmc.org/articles/PMC4660985
Autor:
Jonathan E. Gable, Charles S. Craik, Priyadarshini Jaishankar, Gregory M. Lee, Adam R. Renslo, Brian R. Hearn, Christopher A. Waddling
Publikováno v:
Biochemistry
Herpesviruses rely on a homodimeric protease for viral capsid maturation. A small molecule, DD2, previously shown to disrupt dimerization of Kaposi’s sarcoma-associated herpesvirus protease (KSHV Pr) by trapping an inactive monomeric conformation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5182d8ec477a52578b9cd311082f7ed9
http://europepmc.org/articles/PMC4108181
http://europepmc.org/articles/PMC4108181
Autor:
James A. Kraemer, Marcella L. Erb, Elizabeth A. Montabana, Duy Stephen L. Pham, Joe Pogliano, Katrina Nguyen, Hannah Wang, David A. Agard, Elena A. Zehr, Christopher A. Waddling
Publikováno v:
Cell, vol 149, iss 7
Summary Tubulins are essential for the reproduction of many eukaryotic viruses, but historically, bacteriophage were assumed not to require a cytoskeleton. Here, we identify a tubulin-like protein, PhuZ, from bacteriophage 201φ2-1 and show that it f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964f6c5f8920bb1bef83272e2b983fe9
Publikováno v:
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 60:1-8
The reaction of [24-Pyrim C6][ $$ {\text{NO}}_{{\text{3}}} $$ ]6 · 8H2O with the monopotassium salt of acetylenedicarboxylic acid yielded single crystals of [24-Pyrim C6][C4O4]2[ $$ {\text{NO}}_{{\text{3}}} $$ ]2 · 7H2O, (1). The compound crystalli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f30bb4c973110f4a0ed01097c6659f8
https://doi.org/10.1007/s10847-007-9343-y
https://doi.org/10.1007/s10847-007-9343-y
Publikováno v:
Protein Science. 10:988-996
The crystal structures of a deletion mutant of human thymidylate synthase (TS) and its ternary complex with dUMP and Tomudex have been determined at 2.0 Å and 2.5 Å resolution, respectively. The mutant TS, which lacks 23 residues near the amino t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8acc5f6c01d5809b00ccf8e4da19930
https://doi.org/10.1110/ps.47601
https://doi.org/10.1110/ps.47601
Publikováno v:
Biochemistry. 39:7878-7885
Endo-beta-N-acetylglucosaminidase F(3) cleaves the beta(1-4) link between the core GlcNAc's of asparagine-linked oligosaccharides, with specificity for biantennary and triantennary complex glycans. The crystal structures of Endo F(3) and the complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81328e30dcc1d0d4b8b5ec511d9d2ec4
https://doi.org/10.1021/bi0001731
https://doi.org/10.1021/bi0001731
Publikováno v:
Journal of the Chemical Society, Dalton Transactions. :1675-1684
Reflux of thiamin [3-(4-amino-2-methylpyrimidin-5-ylmethyl)-5-(2-hydroxyethyl)-4-methylth iazolium] mononitrate in methanol for 2 h, followed by recrystallization from methanol, produced single crystals of [L][NO 3 ] 6 ·16H 2 O {L = 5,12,19,26,33,40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e9f1911522e75f582f14a98435c1480
https://doi.org/10.1039/a607235f
https://doi.org/10.1039/a607235f
Publikováno v:
Macromolecules. 29:3401-3408
Aminolysis of the halogenated poly(thionylphosphazene) [NSOCl(NPCl2)2]n (2a), which possesses a novel S(VI)−N−P backbone, with a series of primary amines NH2R (R = Me, Et, nPr, allyl, nBu, nHex, and Ph) afforded the hydrolytically stable poly[(am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05ab1492372b62710f5172e82882aa5d
https://doi.org/10.1021/ma951611s
https://doi.org/10.1021/ma951611s
Publikováno v:
Inorganic Chemistry. 33:5912-5919
Metal rotaxane complexes of a-cyclodextrin (a-CD), [ (NC)~F~(~~Z(CH~),R.~-CD)F~(CN)~]~-, have been prepared by the reactions of labile [Fe(CN)50H2I3- ions with pre-threaded dicationic bridging ligands [pyz(CH2),RI2+ (pyz = pyrazinium, R = pyrazinium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65433eeea52475f23d2e14e6276cf70f
https://doi.org/10.1021/ic00103a045
https://doi.org/10.1021/ic00103a045