Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christopher A. Simeone"'
Autor:
Christopher A. Simeone, Joseph L. Wilkerson, Annelise M. Poss, James A. Banks, Joseph V. Varre, Jose Lazaro Guevara, Edgar Javier Hernandez, Bushra Gorsi, Donald L. Atkinson, Tursun Turapov, Scott G. Frodsham, Julio C. Fierro Morales, Kristina O’Neil, Barry Moore, Mark Yandell, Scott A. Summers, Andrzej S. Krolewski, William L. Holland, Marcus G. Pezzolesi
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-8 (2022)
Abstract Adiponectin, encoded by ADIPOQ, is an insulin-sensitizing, anti-inflammatory, and renoprotective adipokine that activates receptors with intrinsic ceramidase activity. We identified a family harboring a 10-nucleotide deletion mutation in ADI
Externí odkaz:
https://doaj.org/article/250d25ef59fc4c589b2a1e3ae70ec7b4
Autor:
Christopher A. Simeone, Joseph L. Wilkerson, Annelise M. Poss, James A. Banks, Joseph V. Varre, Jose Lazaro Guevara, Edgar Javier Hernandez, Bushra Gorsi, Donald L. Atkinson, Tursun Turapov, Scott G. Frodsham, Julio C. Fierro Morales, Kristina O’Neil, Barry Moore, Mark Yandell, Scott A. Summers, Andrzej S. Krolewski, William L. Holland, Marcus G. Pezzolesi
Publikováno v:
NPJ genomic medicine. 7(1)
Adiponectin, encoded by ADIPOQ, is an insulin-sensitizing, anti-inflammatory, and renoprotective adipokine that activates receptors with intrinsic ceramidase activity. We identified a family harboring a 10-nucleotide deletion mutation in ADIPOQ that
Autor:
Scott G. Frodsham, Melissa H. Pezzolesi, Julio Fierro-Morales, A. Hunter Wright, River Gunville, Jose Lazaro-Guevara, Nirupama Ramkumar, Courtney A. Zaffino, Christopher A. Simeone, Marcus G. Pezzolesi, Laith Al-Rabadi
Publikováno v:
Am J Nephrol
Introduction: Diabetes is the most common cause of chronic kidney disease (CKD). For patients with diabetes and CKD, the underlying cause of their kidney disease is often assumed to be a consequence of their diabetes. Without histopathological confir
Publikováno v:
Obesity and Diabetes ISBN: 9783030533694
Diabetic kidney disease (DKD) is a microvascular complication of progressive renal decline in patients with diabetes, which is the leading cause of end-stage renal disease (ESRD) globally. Early epidemiological and genetic studies demonstrated that D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e79f6b03e6466ab17d94b33a3a17e20
https://doi.org/10.1007/978-3-030-53370-0_17
https://doi.org/10.1007/978-3-030-53370-0_17
Autor:
Pierre-Jean Saulnier, Jihwan Park, Katalin Susztak, Zaipul I. Md Dom, Alessandro Doria, Monika A. Niewczas, Carl F. Ware, Kevin L. Duffin, Jonathan M. Wilson, Andrew Schlafly, Robert G. Nelson, Meda E. Pavkov, Jan Skupien, Paolo Fiorina, Hetal Shah, Adam M. Smiles, Jennifer K. Sun, Christopher A Simeone, Chengxiang Qiu, Helen C. Looker, Eiichiro Satake, Matthias Kretzler, Andrzej S. Krolewski, Viji Nair
Publikováno v:
Nature medicine
Chronic inflammation is postulated to be involved in development of end stage renal disease (ESRD) in diabetes, but which specific circulating inflammatory proteins contribute to this risk remains unknown. To study this we examined 194 circulating in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa1b0194a4d6443ea1040c851ce20974
https://ruj.uj.edu.pl/xmlui/handle/item/112643
https://ruj.uj.edu.pl/xmlui/handle/item/112643
Autor:
John Tsay, Jan K. Skupien, Katalin Susztak, Andrzej Krolewski, Wenjun Ju, Christopher A. Simeone, Adam Smiles, Monika Niewczas, Jihwan Park, Matthias Kretzler, V. Nair, Eiichiro Satake
Publikováno v:
Diabetes. 67
We conducted an untargeted proteomic profiling of circulating inflammatory proteins using SOMASCAN platform to find those that predicted 10-year ESRD risk in two cohort study. Subjects with Type 1 Diabetes (T1D) served as a discovery cohort and a T2D
Publikováno v:
Pharmacology & Toxicology. 78:44-49
Rolipram is a selective inhibitor of Type IV phosphodiesterase isozymes (PDE IV) which is often used as a baseline comparator for compounds in this class. To document the toxicological effects of rolipram, it was administered to female rats at 0, 10,