Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Christopher A. Fasano"'
Retraction Notice to: NPTX1 Regulates Neural Lineage Specification from Human Pluripotent Stem Cells
Autor:
Nathan C. Boles, Sarah E. Hirsch, Sheila Le, Barbara Corneo, Fadi Najm, Andrew P. Minotti, Qingjie Wang, Steven Lotz, Paul J. Tesar, Christopher A. Fasano
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113625- (2024)
Externí odkaz:
https://doaj.org/article/7d0dbdd8172d4352a1d70f452496b269
Autor:
Nathan C. Boles, Sarah E. Hirsch, Sheila Le, Barbara Corneo, Fadi Najm, Andrew P. Minotti, Qingjie Wang, Steven Lotz, Paul J. Tesar, Christopher A. Fasano
Publikováno v:
Cell Reports, Vol 6, Iss 4, Pp 724-736 (2014)
Neural induction is the first fundamental step in nervous system formation. During development, a tightly regulated niche modulates transient extracellular signals to influence neural lineage commitment. To date, however, the cascade of molecular eve
Externí odkaz:
https://doaj.org/article/95bbf450f8af451583aca65d7d5f7cb4
Autor:
Justin K. Ichida, Michael Manganiello, Daylon James, Scott Noggle, David J. Kahler, Christopher A. Fasano, Dieter Egli, Susan L. Solomon, Kristin A. Smith, David Mckeon, Darja Marolt, Zach W. Hall, Caroline Marshall
Publikováno v:
Annals of the New York Academy of Sciences. 1189:E1-E15
Sponsored by the New York Stem Cell Foundation (NYSCF), the "Fourth Annual Translational Stem Cell Research Conference: Breaking Ground" convened October 13-14, 2009 at The Rockefeller University in New York City to discuss translational stem cell re
Autor:
Michel Sadelain, Eirini P. Papapetrou, Fumiko Shimizu, Lorenz Studer, Viviane Tabar, Hyesoo Kim, Stuart M. Chambers, Yosif Ganat, Gabsang Lee, Agnes Viale, Mark J. Tomishima, Jayanthi Menon, Christopher A. Fasano
Publikováno v:
Nature
SUMMARY The isolation of human induced pluripotent stem cells (iPSCs)1-3 offers a novel strategy for modeling human disease. Recent studies have reported the derivation and differentiation of disease-specific human iPSCs4-7. However, a key challenge
Autor:
Randolph S. Ashton, David V. Schaffer, Sally Temple, Joseph Peltier, Christopher A. Fasano, Analeah O'Neill, Ravi S. Kane, Joshua N. Leonard
Publikováno v:
Stem Cells. 25:2928-2935
We describe a microarray-based approach for the high-throughput screening of gene function in stem cells and demonstrate the potential of this method by growing and isolating clonal populations of both adult and embryonic neural stem cells. Clonal mi
Autor:
Natalia Lowry, Ihor R. Lemischka, Christopher A. Fasano, Sally Temple, Natalia Ivanova, John T. Dimos
Publikováno v:
Cell Stem Cell. 1(1):87-99
SummaryKnockout studies have shown that the polycomb gene Bmi-1 is important for postnatal, but not embryonic, neural stem cell (NSC) self-renewal and have identified the cell-cycle inhibitors p16/p19 as molecular targets. Here, using lentiviral-deli
Autor:
Sally Temple, John T. Dimos, Timothy N. Phoenix, Edward E. Morrisey, Natalia Ivanova, Stefano Stifani, Yue Wang, Ihor R. Lemischka, Christopher A. Fasano, Qin Shen
Publikováno v:
Nature Neuroscience. 9:743-751
In the developing cerebral cortex, neurons are born on a predictable schedule. Here we show in mice that the essential timing mechanism is programmed within individual progenitor cells, and its expression depends solely on cell-intrinsic and environm
Autor:
Ravi S. Kane, Steven Lotz, Jeffrey H. Stern, Barbara Corneo, Sally Temple, Faizzan Ahmad, Susan K. Goderie, Sheila Le, Nicolas Tokas, Sarah E. Hirsch, Christopher A. Fasano, Akhilesh Banerjee
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 2, p e56289 (2013)
PLoS ONE, Vol 8, Iss 2, p e56289 (2013)
An essential aspect of stem cell culture is the successful maintenance of the undifferentiated state. Many types of stem cells are FGF2 dependent, and pluripotent stem cells are maintained by replacing FGF2-containing media daily, while tissue-specif
Autor:
Erzsebet Kokovay, Ihor R. Lemischka, John T. Dimos, Yechiel Elkabetz, Natalia Lowry, Timothy N. Phoenix, Lorenz Studer, Christopher A. Fasano, Sally Temple
Neural stem cells (NSCs) persist throughout life in two forebrain areas: the subventricular zone (SVZ) and the hippocampus. Why forebrain NSCs self-renew more extensively than those from other regions remains unclear. Prior studies have shown that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c189b6b91b2c71c2a51b34cb85cc16
https://europepmc.org/articles/PMC2658524/
https://europepmc.org/articles/PMC2658524/
Autor:
Lorenz Studer, Stuart M. Chambers, Mark J. Tomishima, Eirini P. Papapetrou, Christopher A. Fasano, Michel Sadelain
Publikováno v:
Nature biotechnology
Current neural induction protocols for human embryonic stem (hES) cells rely on embryoid body formation, stromal feeder co-culture or selective survival conditions. Each strategy has considerable drawbacks, such as poorly defined culture conditions,