Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Christopher A. D'Souza"'
Autor:
Amy Han, Olav Olsen, Sokol Haxhinasto, Zaruhi Hovhannisyan, Jean Yanolatos, Frank Delfino, Feng Zhao, Christopher A. D’Souza, Jing Shan, William C. Olson
Publikováno v:
Journal of Medicinal Chemistry. 64:11958-11971
Glucocorticoids (GCs) are widely used to treat a variety of autoimmune and inflammatory diseases; however, systemic delivery of GCs is associated with side effects that affect essentially every organ system, reflecting the nearly ubiquitous expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6919fd0ec17eeb36a2836a42db4e337d
https://doi.org/10.1021/acs.jmedchem.1c00541
https://doi.org/10.1021/acs.jmedchem.1c00541
Publikováno v:
International Society of Hair Restoration Surgery. 28:239-243
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b59c412e5ad6849f58c6d43c539520e
https://doi.org/10.33589/28.6.0239
https://doi.org/10.33589/28.6.0239
Autor:
Sandra Coetzee, Jing Shan, Sosina Makonnen, Thomas Nittoli, Christopher A. D’Souza, Ishita Chatterjee, Yu Wang, Marcus Kelly, Arthur Kunz, Carlos Hickey, Julian Andreev, Jason T. Giurleo, Jessica R. Kirshner, Pamela Trail, Frank Delfino, Sumreen Jalal, Terra Potocky, Gavin Thurston
Publikováno v:
Molecular Cancer Therapeutics. 16:1299-1311
The Prolactin Receptor (PRLR) is a type 1 cytokine receptor that is expressed in a subset of breast cancers and may contribute to its pathogenesis. It is relatively overexpressed in approximately 25% of human breast tumors while expressed at low leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36266e1db7aaa213158084d9f8585d30
https://doi.org/10.1158/1535-7163.mct-16-0839
https://doi.org/10.1158/1535-7163.mct-16-0839
Publikováno v:
AIAA Scitech 2020 Forum.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03f9e05980e5f867cf0f1759f6064441
https://doi.org/10.2514/6.2020-0229
https://doi.org/10.2514/6.2020-0229
Autor:
Peter Laverman, Robert M. Sharkey, Otto C. Boerman, Annemarie Eek, Wim J.G. Oyen, David M. Goldenberg, Christopher A. D’Souza, William J. McBride
Publikováno v:
Tumor Biology, 33, 427-34
Tumor Biology, 33, 2, pp. 427-34
Tumour Biology
Tumor Biology, 33, 2, pp. 427-34
Tumour Biology
Contains fulltext : 108912.pdf (Publisher’s version ) (Open Access) We recently reported a facile method based on the chelation of [(18)F]aluminum fluoride (Al(18)F) by NOTA (1,4,7-triazacyclononane-1,4,7-triacetic acid). Here, we present a further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9046844a7d3deb841e35d1c38c76ccdb
https://doi.org/10.1007/s13277-011-0250-x
https://doi.org/10.1007/s13277-011-0250-x
Autor:
Karam El-Bayoumy, Gang Chen, Christopher A. D'Souza, Dhimant Desai, Ryan J. Arner, Ujjawal H. Gandhi, Hema Vunta, Naveen Kaushal, Shantu Amin, K. Sandeep Prabhu
Publikováno v:
Chemico-Biological Interactions. 188:446-456
Celecoxib is a selective cyclooxygenase (COX)-2 inhibitor used to treat inflammation, while selenium is known to down-regulate the transcription of COX-2 and other pro-inflammatory genes. To expand the anti-inflammatory property, wherein celecoxib co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164629c947fc2e8579d8d9f1e424fc8a
https://doi.org/10.1016/j.cbi.2010.09.021
https://doi.org/10.1016/j.cbi.2010.09.021
Autor:
Christopher A. D’Souza, Thomas M. Cardillo, Serengulam V. Govindan, Hans J. Hansen, David M. Goldenberg, Sung-Ju Moon
Publikováno v:
Journal of Medicinal Chemistry. 51:6916-6926
CPT-11 is a clinically used cancer drug, and it is a prodrug of the potent topoisomerase I inhibitor, SN-38 (7-ethyl-10-hydroxycamptothecin). To bypass the need for the in vivo conversion of CPT-11 and increase the therapeutic index, bifunctional der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d9bab0b352a9230d1352b366d6c804
https://doi.org/10.1021/jm800719t
https://doi.org/10.1021/jm800719t
Publikováno v:
Organometallics. 22:1626-1629
We find that alkenes isomerize rapidly in the presence of catalytic amounts of a hydroborating reagent and a rhodium compound. The hydroborating reagent is apparently responsible for the in situ generation of a metal hydride species, which has been i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::288dd99791f123d06233b87d9ff5f522
https://doi.org/10.1021/om0207358
https://doi.org/10.1021/om0207358
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 46:851-859
Isothiocyanates have gained considerable attention for their role as potent chemopreventive agents. Sulforaphane, 1a (SFN), a naturally occurring isothiocyanate, was isotopically labelled in five steps starting from 3-(methylthio)-1-propanol (2). Rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::997d04cdc88d049a5b40e2e3f86dbc65
https://doi.org/10.1002/jlcr.724
https://doi.org/10.1002/jlcr.724
Autor:
Christopher A. D’Souza, David M. Goldenberg, Gerben M. Franssen, Charles J. Smith, Otto C. Boerman, Ingrid Dijkgraaf, William J. McBride, Wim J.G. Oyen, Peter Laverman
Publikováno v:
The Journal of Nuclear Medicine (1978), 53, 947-52
The Journal of Nuclear Medicine (1978), 53, 6, pp. 947-52
The Journal of Nuclear Medicine (1978), 53, 6, pp. 947-52
Item does not contain fulltext The gastrin-releasing peptide receptor (GRPR) is overexpressed in human prostate cancer. Bombesin (BBN) is a neurotransmitter of 14 amino acids and binds with selectivity and with high affinity to GRPRs. We have synthes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f60d2d33ec9b76776e4d8a8cc0d82e2
https://pubmed.ncbi.nlm.nih.gov/22570329
https://pubmed.ncbi.nlm.nih.gov/22570329