Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Christopher A Werley"'
Autor:
Christopher A Werley, Miao-Ping Chien, Jellert Gaublomme, Karthik Shekhar, Vincent Butty, B Alexander Yi, Joel M Kralj, William Bloxham, Laurie A Boyer, Aviv Regev, Adam E Cohen
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0172671 (2017)
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are a promising platform for cardiac studies in vitro, and possibly for tissue repair in humans. However, hiPSC-CM cells tend to retain morphology, metabolism, patterns of gene exp
Externí odkaz:
https://doaj.org/article/23e59abed85b48d2860c1c438a159503
Autor:
Mark J Henderson, Heather A Baldwin, Christopher A Werley, Stefano Boccardo, Leslie R Whitaker, Xiaokang Yan, Graham T Holt, Eric R Schreiter, Loren L Looger, Adam E Cohen, Douglas S Kim, Brandon K Harvey
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139273 (2015)
Endoplasmic reticulum calcium homeostasis is critical for cellular functions and is disrupted in diverse pathologies including neurodegeneration and cardiovascular disease. Owing to the high concentration of calcium within the ER, studying this subce
Externí odkaz:
https://doaj.org/article/161ea35e86594287bc3d469f5096851a
Autor:
Jeehae Park, Christopher A Werley, Veena Venkatachalam, Joel M Kralj, Sulayman D Dib-Hajj, Stephen G Waxman, Adam E Cohen
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e85221 (2013)
Development of improved fluorescent voltage indicators is a key challenge in neuroscience, but progress has been hampered by the low throughput of patch-clamp characterization. We introduce a line of non-fluorescent HEK cells that stably express NaV
Externí odkaz:
https://doaj.org/article/b36bdf06c1f44ba09bf334ed1edcc186
Autor:
Prasahnt Sivarajah, Benjamin K Ofori-Okai, Stephanie M Teo, Christopher A Werley, Keith A Nelson
Publikováno v:
New Journal of Physics, Vol 17, Iss 1, p 013013 (2015)
Electromagnetic homogenization approximation calculates an effective refractive index of a composite material as a weighted average of its components, and has found uses in gradient refractive index and transformation optics devices. However, the uti
Externí odkaz:
https://doaj.org/article/c5d09c496c6e4506bdf133eef4459119
Autor:
Benjamin K Ofori-Okai, Prasahnt Sivarajah, Christopher A Werley, Stephanie M Teo, Keith A Nelson
Publikováno v:
New Journal of Physics, Vol 16, Iss 5, p 053003 (2014)
We demonstrate for the first time the ability to perform time resolved imaging of terahertz (THz) waves propagating within a photonic crystal (PhC) slab. For photonic lattices with different orientations and symmetries, we used the electro-optic effe
Externí odkaz:
https://doaj.org/article/09bd0282ddbe46ee99498fb743551184
Autor:
Christopher A. Werley, Stefano Boccardo, Alessandra Rigamonti, Emil M. Hansson, Adam E. Cohen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Existing fluorescent protein-based sensor measurements are limited to 4 or fewer simultaneously recorded modalities due to spectral overlap. Here the authors introduce Multiplexed Optical Sensors in Arrayed Islands of Cells (MOSAIC), which enables pa
Externí odkaz:
https://doaj.org/article/da5fa069ae7f4bf7a1f2a81128754790
Autor:
He Tian, Hunter C. Davis, J. David Wong-Campos, Pojeong Park, Linlin Z. Fan, Benjamin Gmeiner, Shahinoor Begum, Christopher A. Werley, Gabriel B. Borja, Hansini Upadhyay, Himali Shah, Jane Jacques, Yitong Qi, Vicente Parot, Karl Deisseroth, Adam E. Cohen
Publikováno v:
Nature Methods.
Autor:
Pin W. Liu, Hongkang Zhang, Christopher A. Werley, Monika Pichler, Steve Ryan, Caitlin Lewarch, Jane Jacques, Jennifer Grooms, John Ferrante, Guangde Li, Dawei Zhang, Nate Bremmer, Adam Barnett, Romina Chantre, Amy E. Elder, Adam E. Cohen, Luis A. Williams, Graham T. Dempsey, Owen B. McManus
Chronic pain associated with osteoarthritis (OA) remains an intractable problem with few effective treatment options. New approaches are needed to model the disease biology and to drive discovery of therapeutics. Here, we present anin vitromodel of O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::088799b6f5f999c7b434c1b6a4461ccb
https://doi.org/10.1101/2022.12.12.520139
https://doi.org/10.1101/2022.12.12.520139
Autor:
He Tian, Hunter C. Davis, J. David Wong-Campos, Pojeong Park, Linlin Z. Fan, Benjamin Gmeiner, Shahinoor Begum, Christopher A. Werley, Gabriel B. Borja, Hansini Upadhyay, Himali Shah, Jane Jacques, Yitong Qi, Vicente Parot, Karl Deisseroth, Adam E. Cohen
Publikováno v:
Nature Methods. 20:469-469
Autor:
Gabriel B. Borja, Hongkang Zhang, Benjamin N. Harwood, Jane Jacques, Jennifer Grooms, Romina O. Chantre, Dawei Zhang, Adam Barnett, Christopher A. Werley, Yang Lu, Steven F. Nagle, Owen B. McManus, Graham T. Dempsey
Publikováno v:
Frontiers in molecular neuroscience. 15
Optogenetic assays provide a flexible, scalable, and information rich approach to probe compound effects for ion channel drug targets in both heterologous expression systems and associated disease relevant cell types. Despite the potential utility an