Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Christopher A Seid"'
Autor:
Christopher A. Seid, Kathryn M. Jones, Jeroen Pollet, Brian Keegan, Elissa Hudspeth, Molly Hammond, Junfei Wei, C. Patrick McAtee, Leroy Versteeg, Amanda Gutierrez, Zhuyun Liu, Bin Zhan, Jonathan L. Respress, Ulrich Strych, Maria Elena Bottazzi, Peter J. Hotez
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 3, Pp 621-633 (2017)
A therapeutic vaccine for human Chagas disease is under development by the Sabin Vaccine Institute Product Development Partnership. The aim of the vaccine is to significantly reduce the parasite burden of Trypanosoma cruzi in humans, either as a stan
Externí odkaz:
https://doaj.org/article/0ca4efae01d142dba065dcb9f0fd453d
Autor:
Neima Briggs, Junfei Wei, Leroy Versteeg, Bin Zhan, Brian Keegan, Ashish Damania, Jeroen Pollet, Kelly S Hayes, Coreen Beaumier, Christopher A Seid, Jamie Leong, Richard K Grencis, Maria Elena Bottazzi, K Jagannadha Sastry, Peter J Hotez
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007273 (2018)
Human whipworm (Trichuris trichiura) infects approximately 1 in 15 people worldwide, representing the leading infectious cause of colitis and subsequent, inflammatory bowel disease (IBD). Current control measures focused on mass deworming have had li
Externí odkaz:
https://doaj.org/article/c52d2e12e4f3409e9ebdb58ff06a1b09
Autor:
Oluwatoyin A Asojo, Alan Kelleher, Zhuyun Liu, Jeroen Pollet, Elissa M Hudspeth, Wanderson C Rezende, Mallory Jo Groen, Christopher A Seid, Maha Abdeladhim, Shannon Townsend, Waldione de Castro, Antonio Mendes-Sousa, Daniella Castanheira Bartholomeu, Ricardo Toshio Fujiwara, Maria Elena Bottazzi, Peter J Hotez, Bin Zhan, Fabiano Oliveira, Shaden Kamhawi, Jesus G Valenzuela
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 3, p e0005374 (2017)
BACKGROUND:Immunity to the sand fly salivary protein SALO (Salivary Anticomplement of Lutzomyia longipalpis) protected hamsters against Leishmania infantum and L. braziliensis infection and, more recently, a vaccine combination of a genetically modif
Externí odkaz:
https://doaj.org/article/79f22f7975c54654901cb554512a5886
Autor:
Peter J. Hotez, Maria Elena Bottazzi, Amadeo B. Biter, Wen-Hsiang Chen, Jeroen Pollet, Elissa M. Hudspeth, Christopher A. Seid, Sarah Weltje, C. Patrick McAtee, Ulrich Strych
Publikováno v:
Journal of Pharmaceutical Sciences. 107:1468-1473
Chagas disease due to chronic infection with Trypanosoma cruzi is a neglected cause of heart disease, affecting approximately 6-10 million individuals in Latin America and elsewhere. T. cruzi Tc24, a calcium-binding protein in the flagellar pocket of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1550814f90d6c3d82e5524dbe9b160d3
https://doi.org/10.1016/j.xphs.2017.12.014
https://doi.org/10.1016/j.xphs.2017.12.014
Autor:
Mun Peak Nyon, Shibo Jiang, Lanying Du, Bi Hung Peng, Jeroen Pollet, Wanbo Tai, Abdullah Algaissi, Kevin S. Naceanceno, Christopher A. Seid, Chien Te K. Tseng, Ulrich Strych, Maria Elena Bottazzi, Anurodh S. Agrawal, Peter J. Hotez
Publikováno v:
Vaccine
Middle East respiratory syndrome coronavirus (MERS-CoV) has infected at least 2040 patients and caused 712 deaths since its first appearance in 2012, yet neither pathogen-specific therapeutics nor approved vaccines are available. To address this need
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39d616f9ac87b0a2741b5a1f37754cf
3M-052 as an adjuvant for a PLGA microparticle-based Leishmania donovani recombinant protein vaccine
Autor:
Christopher A. Seid, Elissa M. Hudspeth, Qian Wang, Meagan A. Barry, C. Patrick McAtee, Michael J. Heffernan
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 106:1587-1594
It is believed that an effective vaccine against leishmaniasis will require a T helper type 1 (TH 1) immune response. In this study, we investigated the adjuvanticity of the Toll-like receptor (TLR) 7/8 agonist 3M-052 in combination with the Leishman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::421772236e84c320789e14088d6ad793
https://doi.org/10.1002/jbm.b.33965
https://doi.org/10.1002/jbm.b.33965
Autor:
Jeroen Pollet, Wanderson C. Rezende, Shivali M. Chag, Elissa M. Hudspeth, Wen-Hsiang Chen, Peter J. Hotez, Maria Elena Bottazzi, Mohan Vivekanandan Poongavanam, Ulrich Strych, Amadeo B. Biter, C. Patrick McAtee, Ebe A. Ewere, Christopher A. Seid
Publikováno v:
Journal of Pharmaceutical Sciences
Journal of pharmaceutical sciences
Journal of pharmaceutical sciences
From 2002 to 2003, a global pandemic of severe acute respiratory syndrome (SARS) spread to 5 continents and caused 8000 respiratory infections and 800 deaths. To ameliorate the effects of future outbreaks as well as to prepare for biodefense, a proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccafe0e317b14d61d49442b99854e51c
Autor:
Vladimir Cruz-Chan, Maria Elena Bottazzi, Eric Dumonteil, Bin Zhan, Molly Hammond, Zhuyun Liu, Brian Keegan, Junfei Wei, Elissa M. Hudspeth, Raul Arjona-Sabido, C. Patrick McAtee, Christopher A. Seid, Peter J. Hotez
Publikováno v:
Protein Expression and Purification. 130:129-136
The nucleoside hydrolase gene from Leishmania donovani was cloned and expressed in Escherichia coli as a full length 36-kDa protein (LdNH36). Following lysis and extraction, the protein was purified by anion exchange and gel filtration chromatography
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8301496deadb791bc1b7575e4e084b7
https://doi.org/10.1016/j.pep.2016.10.008
https://doi.org/10.1016/j.pep.2016.10.008
Autor:
Molly Hammond, Elissa M. Hudspeth, David A. Engler, Risë K. Matsunami, Bin Zhan, Maria Elena Bottazzi, Christopher A. Seid, Ulrich Strych, Zhuyun Liu, Qian Wang, Peter J. Hotez, Oluwatoyin A. Asojo, Junfei Wei, C. Patrick McAtee, Michael J. Heffernan, Jeroen Pollet
Publikováno v:
Human Vaccines & Immunotherapeutics
Leishmania donovani is the major cause of visceral leishmaniasis (kala-azar), now recognized as the parasitic disease with the highest level of mortality second only to malaria. No human vaccine is currently available. A 36 kDa L. donovani nucleoside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df82589bb8222970a13e72c62e0ebb7
https://doi.org/10.1080/21645515.2016.1139254
https://doi.org/10.1080/21645515.2016.1139254
Autor:
Maria Elena Bottazzi, Ashish Damania, Neima Briggs, Richard K. Grencis, Christopher A. Seid, Coreen M. Beaumier, Peter J. Hotez, Leroy Versteeg, Brian Keegan, K. Jagannadha Sastry, Kelly S. Hayes, Bin Zhan, Junfei Wei, Jeroen Pollet, Jamie Leong
Publikováno v:
Briggs, N, Wei, J, Versteeg, L, Zhan, B, Keegan, B, Damania, A, Pollet, J, Hayes, K S, Beaumier, C, Seid, C A, Leong, J, Grencis, R K, Bottazzi, M E, Sastry, K J, Hotez, P J & Mitre, E 2018, ' Trichuris muris whey acidic protein induces type 2 protective immunity against whipworm ', PLoS Pathogens, vol. 14, no. 8, pp. e1007273 . https://doi.org/10.1371/journal.ppat.1007273
PLoS Pathogens, Vol 14, Iss 8, p e1007273 (2018)
PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 8, p e1007273 (2018)
PLoS Pathogens
Human whipworm (Trichuris trichiura) infects approximately 1 in 15 people worldwide, representing the leading infectious cause of colitis and subsequent, inflammatory bowel disease (IBD). Current control measures focused on mass deworming have had li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f51ce6513618dbfc553d5f95485246f
https://dx.plos.org/10.1371/journal.ppat.1007273
https://dx.plos.org/10.1371/journal.ppat.1007273
