Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Christopher A Adase"'
Autor:
Alon Peled, Ofer Sarig, Liat Samuelov, Marta Bertolini, Limor Ziv, Daphna Weissglas-Volkov, Marina Eskin-Schwartz, Christopher A Adase, Natalia Malchin, Ron Bochner, Gilad Fainberg, Ilan Goldberg, Koji Sugawara, Avital Baniel, Daisuke Tsuruta, Chen Luxenburg, Noam Adir, Olivier Duverger, Maria Morasso, Stavit Shalev, Richard L Gallo, Noam Shomron, Ralf Paus, Eli Sprecher
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006369 (2016)
Despite recent advances in our understanding of the pathogenesis of ectodermal dysplasias (EDs), the molecular basis of many of these disorders remains unknown. In the present study, we aimed at elucidating the genetic basis of a new form of ED featu
Externí odkaz:
https://doaj.org/article/2a310f48642d4138a48fbddd5896a7f3
Autor:
Biswa Choudhury, Robert A. Dorschner, Ling-juan Zhang, Richard L. Gallo, Emi Sato, Christopher A. Adase
Publikováno v:
The Journal of investigative dermatology, vol 137, iss 8
Sato, Emi; Zhang, Ling-Juan; Dorschner, Robert A; Adase, Christopher A; Choudhury, Biswa P; & Gallo, Richard L. (2017). Activation of Parathyroid Hormone 2 Receptor Induces Decorin Expression and Promotes Wound Repair.. The Journal of investigative dermatology, 137(8), 1774-1783. doi: 10.1016/j.jid.2017.03.034. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/2vv093n8
Sato, Emi; Zhang, Ling-Juan; Dorschner, Robert A; Adase, Christopher A; Choudhury, Biswa P; & Gallo, Richard L. (2017). Activation of Parathyroid Hormone 2 Receptor Induces Decorin Expression and Promotes Wound Repair.. The Journal of investigative dermatology, 137(8), 1774-1783. doi: 10.1016/j.jid.2017.03.034. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/2vv093n8
In this study, we report that TIP39, a parathyroid hormone ligand family member that was recently identified to be expressed in the skin, can induce decorin expression and enhance wound repair. Topical treatment of mice with TIP39 accelerated wound r
Autor:
Christopher A. Adase, Tatsuya Dokoshi, Mikihiro Fujiya, Ling-juan Zhang, Richard L. Gallo, James A. Sanford, Teruaki Nakatsuji, Hiroki Tanaka, Rudolph D. Paladini
Publikováno v:
JCI insight, vol 3, iss 21
In this study we evaluated the role of hyaluronan (HA) in reactive adipogenesis, a local expansion of preadipocytes that provides host defense by release of antimicrobial peptides. We observed that HA accumulated during maturation of adipocytes in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964964ec943ef0506f6cebef9c9364f7
https://escholarship.org/uc/item/455110qg
https://escholarship.org/uc/item/455110qg
Publikováno v:
Journal of Visualized Experiments.
The keratinocyte (KC) is the predominant cell type in the epidermis, the outermost layer of the skin. Epidermal KCs play a critical role in providing skin defense by forming an intact skin barrier against environmental insults, such as UVB irradiatio
Autor:
Christopher A. Adase, Ling-juan Zhang, Richard L. Gallo, Nikhil Nitin Kulkarni, Arup K. Indra, Daniel J. Coleman, Carlos Aguilera, Fengwu Li, James A. Sanford, Andrew W. Borkowski
Publikováno v:
The Journal of investigative dermatology. 137(11)
In this study, we observed that mice lacking the IL-1 receptor (IL-1R) ( IL1r –/– ) or deficient in IL1-β developed multiple epidermal cysts after chronic UVB exposure. Cysts that developed in IL1r –/– mice were characterized by the presence
Autor:
N. Malchin, Noam Shomron, Limor Ziv, Avital Baniel, Daphna Weissglas-Volkov, Maria I. Morasso, Ofer Sarig, Christopher A. Adase, Daisuke Tsuruta, Gilad Fainberg, Liat Samuelov, Stavit A. Shalev, Alon Peled, Eli Sprecher, Koji Sugawara, Olivier Duverger, R. Bochner, Chen Luxenburg, Ilan Goldberg, Ralf Paus, Richard L. Gallo, Marta Bertolini, Noam Adir, M. Eskin-Schwartz
Publikováno v:
Peled, A, Sarig, O, Samuelov, L, Bertolini, M, Ziv, L, Weissglas-Volkov, D, Eskin-Schwartz, M, Adase, C A, Malchin, N, Bochner, R, Fainberg, G, Goldberg, I, Sugawara, K, Baniel, A, Tsuruta, D, Luxenburg, C, Adir, N, Duverger, O, Morasso, M, Shalev, S, Gallo, R L, Shomron, N, Paus, R & Sprecher, E 2016, ' Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis ', PL o S Genetics, vol. 12, no. 10, pp. e1006369 . https://doi.org/10.1371/journal.pgen.1006369
PLoS Genetics
PLoS Genetics, Vol 12, Iss 10, p e1006369 (2016)
PLoS genetics, vol 12, iss 10
PLoS Genetics
PLoS Genetics, Vol 12, Iss 10, p e1006369 (2016)
PLoS genetics, vol 12, iss 10
Despite recent advances in our understanding of the pathogenesis of ectodermal dysplasias (EDs), the molecular basis of many of these disorders remains unknown. In the present study, we aimed at elucidating the genetic basis of a new form of ED featu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95bbd24fca0fe1dce891229e09d4900
https://doi.org/10.1371/journal.pgen.1006369
https://doi.org/10.1371/journal.pgen.1006369
Autor:
Emi Sato, Christopher A. Adase, Ling-juan Zhang, Richard L. Gallo, Michael R. Williams, James A. Sanford, Andrew W. Borkowski
Publikováno v:
The Journal of biological chemistry, vol 291, iss 22
A critical function for skin is that when damaged it must simultaneously identify the nature of the injury, repair barrier function, and limit the intrusion of pathogenic organisms. These needs are carried out through the detection of damage-associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d83a62694e5aa7142eb171a6a43fce
https://europepmc.org/articles/PMC4882433/
https://europepmc.org/articles/PMC4882433/
Autor:
Eli Sprecher, R. Bochner, Tova Rogers, Ofer Sarig, Qiaoli Li, W.H. Irwin McLean, Ronna Shayevitch, Andrea Gat, N. Malchin, Noam Shomron, Alon Peled, Benjamin D. Yu, Noam Adir, M. Pavlovsky, Yehonatan Gottlieb, Dan Vodo, Emily Warshauer, Gilad Fainberg, Liat Samuelov, Aileen Sandilands, Gil Ast, Stephanie F. MacCallum, Ofer Isakov, Jouni Uitto, Ilan Goldberg, Linda E. Campbell, Noam Erez, Richard L. Gallo, Christopher A. Adase
Publikováno v:
The Journal of investigative dermatology. 137(2)
Congenital erythroderma is a rare and often life-threatening condition, which has been shown to result from mutations in several genes encoding important components of the epidermal differentiation program. Using whole exome sequencing, we identified
Publikováno v:
Biochemistry. 51:1925-1932
Repositioning of the tandem aromatic residues (Trp-209 and Tyr-210) at the cytoplasmic end of the second transmembrane helix (TM2) modulates the signal output of the aspartate/maltose chemoreceptor of Escherichia coli (Tar(Ec)). Here, we directly ass
Publikováno v:
Journal of Investigative Dermatology. 138:S199