Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christopher, Sellick"'
Autor:
Caijuan Zhan, Gholamreza Bidkhori, Hubert Schwarz, Magdalena Malm, Aman Mebrahtu, Ray Field, Christopher Sellick, Diane Hatton, Paul Varley, Adil Mardinoglu, Johan Rockberg, Veronique Chotteau
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101653- (2020)
Summary: Human embryonic kidney cells HEK293 can be used for the production of therapeutic glycoproteins requiring human post-translational modifications. High cell density perfusion processes are advantageous for such production but are challenging
Externí odkaz:
https://doaj.org/article/3527cbee461a49d0a4b65321f003c3e5
Publikováno v:
Biochemical Engineering Journal. 179:108304
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc9fadcde7b40c0858035b3dcef95a81
https://doi.org/10.1016/j.bej.2021.108304
https://doi.org/10.1016/j.bej.2021.108304
Autor:
Caijuan Zhan, Gholamreza Bidkhori, Hubert Schwarz, Magdalena Malm, Aman Mebrahtu, Ray Field, Christopher Sellick, Diane Hatton, Paul Varley, Adil Mardinoglu, Johan Rockberg, Veronique Chotteau
Publikováno v:
iScience
iScience, Vol 23, Iss 11, Pp 101653-(2020)
iScience, Vol 23, Iss 11, Pp 101653-(2020)
Summary Human embryonic kidney cells HEK293 can be used for the production of therapeutic glycoproteins requiring human post-translational modifications. High cell density perfusion processes are advantageous for such production but are challenging d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::11d5e937e2f0e433d98c7612677d066e
https://pubmed.ncbi.nlm.nih.gov/33145483
https://pubmed.ncbi.nlm.nih.gov/33145483
Autor:
Darren, Geoghegan, Claire, Arnall, Diane, Hatton, Joanne, Noble-Longster, Christopher, Sellick, Tarik, Senussi, David C, James
Publikováno v:
Biotechnology and bioengineering. 115(12)
Amino acid transporters (AATs) represent a key interface between the cell and its environment, critical for all cellular processes: Energy generation, redox control, and synthesis of cell and product biomass. However, very little is known about the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::11136c223607b004d44d1a76e08ce5df
https://pubmed.ncbi.nlm.nih.gov/29987891
https://pubmed.ncbi.nlm.nih.gov/29987891
Autor:
Si Nga, Sou, Philip M, Jedrzejewski, Ken, Lee, Christopher, Sellick, Karen M, Polizzi, Cleo, Kontoravdi
Publikováno v:
Biotechnology and Bioengineering
Despite the positive effects of mild hypothermic conditions on monoclonal antibody (mAb) productivity (q mAb) during mammalian cell culture, the impact of reduced culture temperature on mAb Fc‐glycosylation and the mechanism behind changes in the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f06552ac70c9c947d6c2cbdd001b47f0
https://pubmed.ncbi.nlm.nih.gov/27869292
https://pubmed.ncbi.nlm.nih.gov/27869292
Autor:
Si Nga, Sou, Christopher, Sellick, Ken, Lee, Alison, Mason, Sarantos, Kyriakopoulos, Karen M, Polizzi, Cleo, Kontoravdi
Publikováno v:
Biotechnology and bioengineering. 112(6)
The application of mild hypothermic conditions to cell culture is a routine industrial practice used to improve recombinant protein production. However, a thorough understanding of the regulation of dynamic cellular processes at lower temperatures is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3677366bd6da42415a50f38fe9b4ff67
https://pubmed.ncbi.nlm.nih.gov/25545631
https://pubmed.ncbi.nlm.nih.gov/25545631