Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Christopher, Rowley"'
Autor:
Jennifer Kim Penberthy, Heloísa Garcia Claro, Tevfik Kalelioglu, Caroline Centeno, Ahoora Ladoni, Emma Ragone, Christopher Rowley, Elizabeth Hanchak
Publikováno v:
Journal of Scientific Exploration, Vol 38, Iss 1 (2024)
Background: Research indicates that meditation increases mindfulness and paranormal experiences of precognition, telepathy, clairvoyance, and synchronicities. There is limited knowledge about the prevalence or impact of these experiences on meditator
Externí odkaz:
https://doaj.org/article/6b42436cc30740d6bb9ee28d5bdfd99e
Autor:
Andrew Poole, Vijaykumar Karuppiah, Annabelle Hartt, Jaafar N. Haidar, Sylvie Moureau, Tomasz Dobrzycki, Conor Hayes, Christopher Rowley, Jorge Dias, Stephen Harper, Keir Barnbrook, Miriam Hock, Charlotte Coles, Wei Yang, Milos Aleksic, Aimee Bence Lin, Ross Robinson, Joe D. Dukes, Nathaniel Liddy, Marc Van der Kamp, Gregory D. Plowman, Annelise Vuidepot, David K. Cole, Andrew D. Whale, Chandramouli Chillakuri
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Cancers often harbor mutations in genes encoding important regulatory proteins, but therapeutic targeting of these molecules proves difficult due to their high structural similarity to their non-mutated counterpart. Here authors show the engineering
Externí odkaz:
https://doaj.org/article/d2f84672e7fe4eb3b7df368784cf9d36
Autor:
Globahan Ajibola, Christopher Rowley, Dorcas Maruapula, Jean Leidner, Kara Bennett, Kathleen Powis, Roger L. Shapiro, Shahin Lockman
Publikováno v:
Southern African Journal of HIV Medicine, Vol 21, Iss 1, Pp e1-e4 (2020)
Background: To reduce risk of antiretroviral resistance when stopping efavirenz (EFV)-based antiretroviral treatment (ART), staggered discontinuation of antiretrovirals (an NRTI tail) is recommended. However, no data directly support this recommendat
Externí odkaz:
https://doaj.org/article/85c46b34ad0740a6b31cd46f6c981811
Neural Network Potentials (NNPs) have quickly emerged as powerful computational methods for modeling large chemical systems with the accuracy of quantum mechanical methods but at a much smaller computational cost. To make the training and evaluation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9689e1439e38d29f48443383e7e7d82a
https://doi.org/10.26434/chemrxiv-2022-mdz85
https://doi.org/10.26434/chemrxiv-2022-mdz85
Autor:
Andrew, Poole, Vijaykumar, Karuppiah, Annabelle, Hartt, Jaafar N, Haidar, Sylvie, Moureau, Tomasz, Dobrzycki, Conor, Hayes, Christopher, Rowley, Jorge, Dias, Stephen, Harper, Keir, Barnbrook, Miriam, Hock, Charlotte, Coles, Wei, Yang, Milos, Aleksic, Aimee Bence, Lin, Ross, Robinson, Joe D, Dukes, Nathaniel, Liddy, Marc, Van der Kamp, Gregory D, Plowman, Annelise, Vuidepot, David K, Cole, Andrew D, Whale, Chandramouli, Chillakuri
Publikováno v:
Nature communications. 13(1)
Neoantigens derived from somatic mutations are specific to cancer cells and are ideal targets for cancer immunotherapy. KRAS is the most frequently mutated oncogene and drives the pathogenesis of several cancers. Here we show the identification and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09b6f49fe5f2b3f9dd982b4e6d4e47e8
https://pubmed.ncbi.nlm.nih.gov/36088370
https://pubmed.ncbi.nlm.nih.gov/36088370
Autor:
Sarah Lincoln, Mariet Allen, Claire L Cox, Louise P Walker, Kimberly Malphrus, Yushi Qiu, Thuy Nguyen, Christopher Rowley, Naomi Kouri, Julia Crook, V Shane Pankratz, Samuel Younkin, Linda Younkin, Minerva Carrasquillo, Fanggeng Zou, Samer O Abdul-Hay, Wolfdieter Springer, Sigrid B Sando, Jan O Aasly, Maria Barcikowska, Zbigniew K Wszolek, Jada M Lewis, Dennis Dickson, Neill R Graff-Radford, Ronald C Petersen, Elizabeth Eckman, Steven G Younkin, Nilüfer Ertekin-Taner
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64164 (2013)
Leucine rich repeat transmembrane protein 3 (LRRTM3) is member of a synaptic protein family. LRRTM3 is a nested gene within α-T catenin (CTNNA3) and resides at the linkage peak for late-onset Alzheimer's disease (LOAD) risk and plasma amyloid β (A
Externí odkaz:
https://doaj.org/article/4b8767a6bff4419787f56889d10ad6f1
Many drug molecules contain biaryl fragments, resulting in a torsional barrier corresponding to rotation around the bond linking the aryls. The potential energy surfaces of these torsions vary significantly due to steric and electronic effects, ultim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efb5f62162f2587d6fb8cf22d35dcfd
https://doi.org/10.26434/chemrxiv.12780056
https://doi.org/10.26434/chemrxiv.12780056
Targeted Covalent Inhibitors bind to their targets both covalent and non-covalent modes, providing exceptionally high affinity and selectivity. These inhibitors have been effectively employed as inhibitors of protein kinases, with Taunton and coworke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c29a5bbe503054d3241c76c5082d04d
https://doi.org/10.26434/chemrxiv.13132814.v1
https://doi.org/10.26434/chemrxiv.13132814.v1
Autor:
Mohamad Mohebifar, Christopher Rowley
A molecular mechanical model for liquid water is developed that uses a physically-motivated potential to represent Pauli repulsion and dispersion instead of the standard Lennard-Jones potential. The model has three-atomic sites and a virtual site loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d03bae5c919fb55725cd1648ee90db
https://doi.org/10.26434/chemrxiv.12331019
https://doi.org/10.26434/chemrxiv.12331019