Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Christopher, Mulligan"'
Autor:
David B. Sauer, Jennifer J. Marden, Joseph C. Sudar, Jinmei Song, Christopher Mulligan, Da-Neng Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
DASS carboxylate transporters linked to metabolic diseases couple the Na+ gradient to nutrient uptake. Here, the authors unravel the structural basis by which Na+ binding coordinates substrate interactions, revealing a distinct coupling mechanism.
Externí odkaz:
https://doaj.org/article/91c93804bc594b8eab63527045308f23
Autor:
Toby A. Halamka, Jonathan H. Raberg, Jamie M. McFarlin, Adam D. Younkin, Christopher Mulligan, Xiao‐Lei Liu, Sebastian H. Kopf
Publikováno v:
Geobiology. 21:102-118
Publikováno v:
Biochemical Journal
The divalent anion sodium symporter (DASS) family of transporters (SLC13 family in humans) are key regulators of metabolic homeostasis, disruption of which results in protection from diabetes and obesity, and inhibition of liver cancer cell prolifera
Autor:
Christopher Mulligan, Susan Adams, Holger Möller, Tom Whyte, Soundappan SV Soundappan, Julie Brown
Publikováno v:
Abstracts.
Autor:
Christopher Mulligan, Tom Whyte, Susan Adams, Holger Möller, Soundappan SV Soundappan, Julie Brown
Publikováno v:
Abstracts.
Publikováno v:
eLife, Vol 6 (2017)
The number of ions required to drive substrate transport through a secondary active transporter determines the protein’s ability to create a substrate gradient, a feature essential to its physiological function, and places fundamental constraints o
Externí odkaz:
https://doaj.org/article/2c95ae11f56641b4938aab27982b7df7
Autor:
Toby A, Halamka, Jonathan H, Raberg, Jamie M, McFarlin, Adam D, Younkin, Christopher, Mulligan, Xiao-Lei, Liu, Sebastian H, Kopf
Publikováno v:
GeobiologyREFERENCES. 21(1)
Branched glycerol dialkyl glycerol tetraethers (brGDGTs) are bacterial membrane lipids that are frequently employed as paleoenvironmental proxies because of the strong empirical correlations between their relative abundances and environmental tempera
Publikováno v:
The Journal of Biological Chemistry
The divalent anion sodium symporter (DASS) family (SLC13) plays critical roles in metabolic homeostasis, influencing many processes, including fatty acid synthesis, insulin resistance, and adiposity. DASS transporters catalyze the Na+-driven concentr
Autor:
Toby Halamka, Sebastian Kopf, Jamie McFarlin, Adam Younkin, Jonathan Raberg, Xiao-Lei Liu, Nadia Dildar, Christopher Mulligan
Publikováno v:
Goldschmidt2022 abstracts.