Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Christopher, Linington"'
Autor:
Susan L. Lindsay, Aleksandra M. Molęda, Lindsay M. MacLellan, Siew Min Keh, Daniel E. McElroy, Christopher Linington, Carl S. Goodyear, Susan C. Barnett
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-20 (2022)
Abstract One of the therapeutic approaches for the treatment of the autoimmune demyelinating disease, multiple sclerosis (MS) is bone marrow mesenchymal stromal cell (hBM-MSCs) transplantation. However, given their capacity to enhance myelination in
Externí odkaz:
https://doaj.org/article/954754aad64c4f218d94ee53a8ea3d31
Autor:
Colin L. Crawford, Christina Antoniou, Lina Komarek, Verena Schultz, Claire L. Donald, Paul Montague, Susan C. Barnett, Christopher Linington, Hugh J. Willison, Alain Kohl, Michael P. Coleman, Julia M. Edgar
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Zika virus (ZIKV) is a neurotropic flavivirus recently linked to congenital ZIKV syndrome in children and encephalitis and Guillain-Barré syndrome in adults. Neurotropic viruses often use axons to traffic to neuronal or glial cell somas where they e
Externí odkaz:
https://doaj.org/article/776c4c19cb944ab3a5877e0289dc35f0
Autor:
Katja Thümmler, Eran Rom, Thomas Zeis, Maren Lindner, Sarah Brunner, John J. Cole, Diana Arseni, Steve Mücklisch, Julia M. Edgar, Nicole Schaeren-Wiemers, Avner Yayon, Christopher Linington
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Fibroblast growth factor (FGF) signaling contributes to failure of remyelination in multiple sclerosis, but targeting this therapeutically is complicated by its functional pleiotropy. We now identify FGF2 as a factor up-regulated by astrocyt
Externí odkaz:
https://doaj.org/article/7ee1fa64b1394a10aeb801926f69e36f
Autor:
Stephanie L. Cumberworth, Jennifer A. Barrie, Madeleine E. Cunningham, Daniely Paulino Gomes de Figueiredo, Verena Schultz, Adrian J. Wilder-Smith, Benjamin Brennan, Lindomar J. Pena, Rafael Freitas de Oliveira França, Christopher Linington, Susan C. Barnett, Hugh J. Willison, Alain Kohl, Julia M. Edgar
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-16 (2017)
Abstract The recent global outbreak of Zika virus (ZIKV) infection has been linked to severe neurological disorders affecting the peripheral and central nervous systems (PNS and CNS, respectively). The pathobiology underlying these diverse clinical p
Externí odkaz:
https://doaj.org/article/b73958376b6d4e778fc9461729063ac8
Autor:
Verena Schultz, Stephanie L. Cumberworth, Quan Gu, Natasha Johnson, Claire L. Donald, George A. McCanney, Jennifer A. Barrie, Ana Da Silva Filipe, Christopher Linington, Hugh J. Willison, Julia M. Edgar, Susan C. Barnett, Alain Kohl
Publikováno v:
Viruses, Vol 13, Iss 1, p 91 (2021)
Understanding how Zika virus (Flaviviridae; ZIKV) affects neural cells is paramount in comprehending pathologies associated with infection. Whilst the effects of ZIKV in neural development are well documented, impact on the adult nervous system remai
Externí odkaz:
https://doaj.org/article/831ec2b8ad724b8cba8504c3f7c0e208
Autor:
Silvia Bijland, Gemma Thomson, Matthew Euston, Kyriakos Michail, Katja Thümmler, Steve Mücklisch, Colin L. Crawford, Susan C. Barnett, Mark McLaughlin, T. James Anderson, Christopher Linington, Euan R. Brown, Eric R. Kalkman, Julia M. Edgar
Publikováno v:
F1000Research, Vol 8 (2019)
The normal development and maintenance of CNS white matter, and its responses to disease and injury, are defined by synergies between axons, oligodendrocytes, astrocytes and microglia, and further influenced by peripheral components such as the gut m
Externí odkaz:
https://doaj.org/article/2997cc9b14b746b3a967e1f321e623be
Autor:
Jana Remlinger, Maud Bagnoud, Ivo Meli, Marine Massy, Christopher Linington, Andrew Chan, Jeffrey L. Bennett, Robert Hoepner, Volker Enzmann, Anke Salmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8953ca4238d3c295b74f32de84efbc4b
https://doi.org/10.2139/ssrn.4356442
https://doi.org/10.2139/ssrn.4356442
Autor:
Mario Amatruda, Kate Harris, Alina Matis, Andrew L. Davies, Daniel McElroy, Michael Clark, Christopher Linington, Roshni Desai, Kenneth J. Smith
Publikováno v:
Neuropathology and applied neurobiology.
To explore the importance of tissue hypoxia in causing neurological deficits and demyelination in the inflamed CNS, and the value of inspiratory oxygen treatment, using both active and passive experimental autoimmune encephalomyelitis (EAE).Normobari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6006dc7db761fba1bdf07b4bdb845528
https://pubmed.ncbi.nlm.nih.gov/36520661
https://pubmed.ncbi.nlm.nih.gov/36520661
Autor:
Axel Petzold, Tobias Derfuss, Bruno Stankoff, Aksel Siva, Maria Pia Amato, Tanuja Chitnis, Alvaro Cobo-Calvo, Romain Marignier, Sandra Vukusic, Nasrin Asgari, Christopher Linington, Edgar Meinl, Emmanuelle Waubant, Marco Capobianco, Patrick Waters, Hans Lassmann, Ingo Kleiter, Anu Jacob, Sean J. Pittock, Mar Tintoré, Friedemann Paul, Brenda Banwell, Kumaran Deiva, Kazuo Fujihara, Jeffrey Bennett, Jacqueline Palace, Krzysztof Selmaj, Olga Ciccarelli, Anthony Traboulsee, Brian G. Weinshenker, Fabienne Brilot, Jérôme De Seze, Maria Isabel Leite, Harry Alexopoulos, Ho Jin Kim, Anne-Katrin Pröbstel, Douglas Kazutoshi Sato, Bernhard Hemmer, Markus Reindl, Yael Hacohen, Orhan Aktas
Publikováno v:
Marignier, R, Hacohen, Y, Cobo-Calvo, A, Pröbstel, A-K, Aktas, O, Alexopoulos, H, Amato, M-P, Asgari, N, Banwell, B, Bennett, J, Brilot, F, Capobianco, M, Chitnis, T, Ciccarelli, O, Deiva, K, de Sèze, J R, Fujihara, K, Jacob, A, Kim, H J, Kleiter, I, Lassmann, H, Leite, M-I, Linington, C, Meinl, E, Palace, J, Paul, F, Petzold, A, Pittock, S, Reindl, M, Sato, D K, Selmaj, K, Siva, A, Stankoff, B, Tintore, M, Traboulsee, A, Waters, P, Waubant, E, Weinshenker, B, Derfuss, T, Vukusic, S & Hemmer, B 2021, ' Myelin-oligodendrocyte glycoprotein antibody-associated disease ', The Lancet Neurology, vol. 20, no. 9, pp. 762-772 . https://doi.org/10.1016/S1474-4422(21)00218-0
Marignier, R, Hacohen, Y, Cobo-Calvo, A, Pröbstel, A K, Aktas, O, Alexopoulos, H, Amato, M P, Asgari, N, Banwell, B, Bennett, J, Brilot, F, Capobianco, M, Chitnis, T, Ciccarelli, O, Deiva, K, De Sèze, J, Fujihara, K, Jacob, A, Kim, H J, Kleiter, I, Lassmann, H, Leite, M I, Linington, C, Meinl, E, Palace, J, Paul, F, Petzold, A, Pittock, S, Reindl, M, Sato, D K, Selmaj, K, Siva, A, Stankoff, B, Tintore, M, Traboulsee, A, Waters, P, Waubant, E, Weinshenker, B, Derfuss, T, Vukusic, S & Hemmer, B 2021, ' Myelin-oligodendrocyte glycoprotein antibody-associated disease ', The Lancet Neurology, vol. 20, no. 9, pp. 762-772 . https://doi.org/10.1016/S1474-4422(21)00218-0
Marignier, R, Hacohen, Y, Cobo-Calvo, A, Pröbstel, A K, Aktas, O, Alexopoulos, H, Amato, M P, Asgari, N, Banwell, B, Bennett, J, Brilot, F, Capobianco, M, Chitnis, T, Ciccarelli, O, Deiva, K, De Sèze, J, Fujihara, K, Jacob, A, Kim, H J, Kleiter, I, Lassmann, H, Leite, M I, Linington, C, Meinl, E, Palace, J, Paul, F, Petzold, A, Pittock, S, Reindl, M, Sato, D K, Selmaj, K, Siva, A, Stankoff, B, Tintore, M, Traboulsee, A, Waters, P, Waubant, E, Weinshenker, B, Derfuss, T, Vukusic, S & Hemmer, B 2021, ' Myelin-oligodendrocyte glycoprotein antibody-associated disease ', The Lancet Neurology, vol. 20, no. 9, pp. 762-772 . https://doi.org/10.1016/S1474-4422(21)00218-0
Myelin-oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a recently identified autoimmune disorder that presents in both adults and children as CNS demyelination. Although there are clinical phenotypic overlaps between MOGAD, multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce99a149910aa43ddde4dbbf5ef9759b
https://doi.org/10.1016/s1474-4422(21)00218-0
https://doi.org/10.1016/s1474-4422(21)00218-0
Autor:
Thomas J. Anderson, Alain Kohl, Susan C. Barnett, Claire L. Donald, Tom Solomon, Hugh J. Willison, Verena Schultz, Christopher Linington, Margaret Mullin, Julia M. Edgar, Colin L. Crawford, Jennifer A. Barrie
Publikováno v:
Glia. 69:2023-2036
Some children with proven intrauterine Zika virus (ZIKV) infection who were born asymptomatic subsequently manifested neurodevelopmental delays, pointing to impairment of development perinatally and postnatally. To model this, we infected postnatal d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0e7fed438b49d3807225fb8770def9
https://doi.org/10.1002/glia.24010
https://doi.org/10.1002/glia.24010