Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Christopher, Garris"'
Autor:
Hsin-Wei Liao, Christopher Garris, Christina Pfirschke, Steffen Rickelt, Sean Arlauckas, Marie Siwicki, Rainer H. Kohler, Ralph Weissleder, Vibeke Sundvold-Gjerstad, Baldur Sveinbjørnsson, Øystein Rekdal, Mikael J. Pittet
Publikováno v:
Cell Stress, Vol 3, Iss 11, Pp 348-360 (2019)
LTX-315 is an oncolytic peptide that has antitumor efficacy in mice grafted with various tumor cell lines and is currently being tested in phase II clinical trials. Here we aimed to further evaluate LTX-315 in conditional genetic mouse models of canc
Externí odkaz:
https://doaj.org/article/3c2d5b260fbe4adb94f8a76380519ac6
Autor:
Michael F. Cuccarese, J. Matthew Dubach, Christina Pfirschke, Camilla Engblom, Christopher Garris, Miles A. Miller, Mikael J. Pittet, Ralph Weissleder
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Tumour-associated macrophages (TAM) can be used as prognostic indicators in cancer. Here, the authors establish a platform for high-throughput 3D microscopy in murine lung carcinoma that allows to visualize TAMs infiltration throughout the entire lun
Externí odkaz:
https://doaj.org/article/a3110620e30e417bbd3502f5ec747b02
Autor:
Ferdinando Pucci, Steffen Rickelt, Andita P. Newton, Christopher Garris, Ernesto Nunes, Charles Evavold, Christina Pfirschke, Camilla Engblom, Mari Mino-Kenudson, Richard O. Hynes, Ralph Weissleder, Mikael J. Pittet
Publikováno v:
Cell Reports, Vol 17, Iss 7, Pp 1764-1772 (2016)
Co-option of host components by solid tumors facilitates cancer progression and can occur in both local tumor microenvironments and remote locations. At present, the signals involved in long-distance communication remain insufficiently understood. He
Externí odkaz:
https://doaj.org/article/aa982c8c23874ad09beb98265cad7e03
Autor:
Adil I. Daud, Michael D. Rosenblum, Bernard A. Fox, Robert H.I. Andtbacka, Sharron Gargosky, Shailender Bhatia, Carmen Ballesteros-Merino, Carlos Bifulco, Lauren P. Levine, Christopher Garris, Sean P. Arlauckas, Mikael J. Pittet, Lawrence Fong, Murray Francisco, Arielle Oglesby, Donna Bannavong, David A. Canton, Reneta Hermiz, Erica Browning, Robert Pierce, Mai Le, Katy K. Tsai, Christopher G. Twitty, Alain P. Algazi
Treatment related changes in cell type scores
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2dab53da92d4304d25e1a122adb363
https://doi.org/10.1158/1078-0432.22477617
https://doi.org/10.1158/1078-0432.22477617
Autor:
Adil I. Daud, Michael D. Rosenblum, Bernard A. Fox, Robert H.I. Andtbacka, Sharron Gargosky, Shailender Bhatia, Carmen Ballesteros-Merino, Carlos Bifulco, Lauren P. Levine, Christopher Garris, Sean P. Arlauckas, Mikael J. Pittet, Lawrence Fong, Murray Francisco, Arielle Oglesby, Donna Bannavong, David A. Canton, Reneta Hermiz, Erica Browning, Robert Pierce, Mai Le, Katy K. Tsai, Christopher G. Twitty, Alain P. Algazi
Purpose:Tumors with low frequencies of checkpoint positive tumor-infiltrating lymphocytes (cpTIL) have a low likelihood of response to PD-1 blockade. We conducted a prospective multicenter phase II trial of intratumoral plasmid IL-12 (tavokinogene te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd2c239e09f2d5a2524c8e57f19d8f4
https://doi.org/10.1158/1078-0432.c.6529707.v1
https://doi.org/10.1158/1078-0432.c.6529707.v1
Autor:
Adil I. Daud, Michael D. Rosenblum, Bernard A. Fox, Robert H.I. Andtbacka, Sharron Gargosky, Shailender Bhatia, Carmen Ballesteros-Merino, Carlos Bifulco, Lauren P. Levine, Christopher Garris, Sean P. Arlauckas, Mikael J. Pittet, Lawrence Fong, Murray Francisco, Arielle Oglesby, Donna Bannavong, David A. Canton, Reneta Hermiz, Erica Browning, Robert Pierce, Mai Le, Katy K. Tsai, Christopher G. Twitty, Alain P. Algazi
Lesion response data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940014a570fe99ab1b99be080965c229
https://doi.org/10.1158/1078-0432.22477605.v1
https://doi.org/10.1158/1078-0432.22477605.v1
Autor:
Adil I. Daud, Michael D. Rosenblum, Bernard A. Fox, Robert H.I. Andtbacka, Sharron Gargosky, Shailender Bhatia, Carmen Ballesteros-Merino, Carlos Bifulco, Lauren P. Levine, Christopher Garris, Sean P. Arlauckas, Mikael J. Pittet, Lawrence Fong, Murray Francisco, Arielle Oglesby, Donna Bannavong, David A. Canton, Reneta Hermiz, Erica Browning, Robert Pierce, Mai Le, Katy K. Tsai, Christopher G. Twitty, Alain P. Algazi
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25d0cab47894d2b34b9067e043e1f48c
https://doi.org/10.1158/1078-0432.22477611.v1
https://doi.org/10.1158/1078-0432.22477611.v1
Publikováno v:
British Journal of Cancer
Most cancer deaths are caused by metastasis: recurrence of disease by disseminated tumour cells at sites distant from the primary tumour. Large numbers of disseminated tumour cells are released from the primary tumour, even during the early stages of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b99cbef7db1ffd0061713c955d3c18
https://doi.org/10.1038/s41416-021-01309-w
https://doi.org/10.1038/s41416-021-01309-w
Autor:
Christopher Garris, Jason J. Luke
Publikováno v:
Clin Cancer Res
The development of the most successful cancer immunotherapies in solid tumors, immune-checkpoint blockade, has focused on factors regulating T-cell activation. Until recently, the field has maintained a predominately T-cell centric view of immunother
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3193104e2046c837d8f704f0359ba0
https://doi.org/10.1158/1078-0432.ccr-19-1321
https://doi.org/10.1158/1078-0432.ccr-19-1321
Autor:
Jeremy Gungabeesoon, Nicolas A. Gort-Freitas, Máté Kiss, Evangelia Bolli, Marius Messemaker, Marie Siwicki, Mehdi Hicham, Ruben Bill, Peter Koch, Chiara Cianciaruso, Florent Duval, Christina Pfirschke, Michael Mazzola, Solange Peters, Krisztian Homicsko, Christopher Garris, Ralph Weissleder, Allon M. Klein, Mikael J. Pittet
Publikováno v:
Cell. 186:1448-1464.e20
Neutrophils accumulate in solid tumors, and their abundance correlates with poor prognosis. Neutrophils are not homogeneous, however, and could play different roles in cancer therapy. Here, we investigate the role of neutrophils in immunotherapy, lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4243a20d97fd467032576bb1217ffbc
https://doi.org/10.1016/j.cell.2023.02.032
https://doi.org/10.1016/j.cell.2023.02.032