Zobrazeno 1 - 10
of 420
pro vyhledávání: '"Christopher, Clark"'
Autor:
Miriam Rabl, Leonardo Zullo, Piotr Lewczuk, Johannes Kornhuber, Thomas K. Karikari, Kaj Blennow, Henrik Zetterberg, Francesco Bavato, Boris B. Quednow, Erich Seifritz, Armin von Gunten, Christopher Clark, Julius Popp
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Neuropsychiatric symptoms (NPS) are common in older people, may occur early in the development of dementia disorders, and have been associated with faster cognitive decline. Here, our objectives were to investigate whether plasma
Externí odkaz:
https://doaj.org/article/0f38378ecba046c399aaa3cc26c9200c
Autor:
Mildred A Iro, Manish Sadarangani, Michael Absoud, Liberty Cantrell, Wui K Chong, Christopher Clark, Ava Easton, Victoria Gray, Matilda Hill, Rachel Kneen, Ming Lim, Xinxue Liu, Mike Pike, Tom Solomon, Angela Vincent, Louise Willis, Ly-Mee Yu, Andrew J Pollard
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 11, Iss 06 (2024)
Background There are data suggesting that intravenous immunoglobulin treatment has some benefit for certain forms of encephalitis but robust evidence from large randomised controlled trials in children with all-cause encephalitis is lacking. Objectiv
Externí odkaz:
https://doaj.org/article/70a953bda9c54c0d937037aa3e62e556
Autor:
Alexander Neumann, Olena Ohlei, Fahri Küçükali, Isabelle J. Bos, Jigyasha Timsina, Stephanie Vos, Dmitry Prokopenko, Betty M. Tijms, Ulf Andreasson, Kaj Blennow, Rik Vandenberghe, Philip Scheltens, Charlotte E. Teunissen, Sebastiaan Engelborghs, Giovanni B. Frisoni, Oliver Blin, Jill C. Richardson, Régis Bordet, Alberto Lleó, Daniel Alcolea, Julius Popp, Thomas W. Marsh, Priyanka Gorijala, Christopher Clark, Gwendoline Peyratout, Pablo Martinez-Lage, Mikel Tainta, Richard J. B. Dobson, Cristina Legido-Quigley, Christine Van Broeckhoven, Rudolph E. Tanzi, Mara ten Kate, Christina M. Lill, Frederik Barkhof, Carlos Cruchaga, Simon Lovestone, Johannes Streffer, Henrik Zetterberg, Pieter Jelle Visser, Kristel Sleegers, Lars Bertram, EMIF-AD & ADNI study group
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-23 (2023)
Abstract Background Genome-wide association studies (GWAS) of Alzheimer’s disease (AD) have identified several risk loci, but many remain unknown. Cerebrospinal fluid (CSF) biomarkers may aid in gene discovery and we previously demonstrated that si
Externí odkaz:
https://doaj.org/article/f26d48a8fac447809738ca263de2f029
Autor:
Matteo Spinedi, Christopher Clark, Leonardo Zullo, Anja Kerksiek, Giorgio Pistis, Enrique Castelao, Armin von Gunten, Martin Preisig, Dieter Lütjohann, Julius Popp
Publikováno v:
iScience, Vol 27, Iss 2, Pp 109013- (2024)
Summary: Neurodegenerative, vascular, and dementia diseases are linked to dysregulations in cholesterol metabolism. Dietary plant sterols, or phytosterols, may interfere to neurodegeneration and cognitive decline, and have cholesterol-lowering, anti-
Externí odkaz:
https://doaj.org/article/679ba0983d91415e9526cf37ffdc8e96
Autor:
Simon Nadel, Claire Cameron, David Pace, Rachel Kneen, Matilda Hill, Federico Martinón-Torres, Tom Solomon, Mandy Wan, Angela Vincent, Michael Absoud, Patrick Waters, Manish Sadarangani, Xinxue Liu, Andrew J Pollard, Sanjay Bhate, Ly-Mee Yu, John Alexander, Sarosh Irani, David Kerr, Andrew Collinson, Ava Easton, William Whitehouse, Ming Lim, Emma Plested, Paul Heath, Dominic Smith, Michael Pike, Adilia Warris, Anna Riddell, Paddy McMaster, Simon Kerridge, Louise Willis, Christopher Clark, Victoria Gray, Jay Shetty, John Livingston, Kling Chong, Vishal Mehta, Charles Warlow, Jo Haviland, Alice Jollands, Shakeel Herwitker, Daniel O’Connor, Yama Mujadidi, Lauren Burke, Mildred Iro, Sagida Bibi, Liberty Cantrell, Mike Pike, Chris A. Clark, Sophie Bradshaw, Svetlana Milca, Mike Bale, Sonia Bale, Alan Percival, Meryn Voysey, Amy Beveridge, Amber Thompson, Parvinder Alley, Archana Desurkar, Elma Stephen, Steve Welch, Kayal Vijayakumar, Leena Mewasingh, Christian de Goede
Publikováno v:
BMJ Open, Vol 13, Iss 11 (2023)
Objective To investigate whether intravenous immunoglobulin (IVIG) improves neurological outcomes in children with encephalitis when administered early in the illness.Design Phase 3b multicentre, double-blind, randomised placebo-controlled trial.Sett
Externí odkaz:
https://doaj.org/article/d95df2e0dc6244059c752071a77d38ed
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2022)
Abstract Introduction Neuropsychiatric symptoms are important treatment targets in the management of dementia and can be present at very early clinical stages of neurodegenerative diseases. Increased cortisol has been reported in Alzheimer’s diseas
Externí odkaz:
https://doaj.org/article/3b8af2572b7f4cec8529d98b182096a5
Publikováno v:
JEM Reports, Vol 2, Iss 2, Pp 100029- (2023)
Background: Emergency physician use of transesophageal echocardiography (TEE) is emerging as a promising tool to aid diagnosis and treatment during resuscitation. Case report: We present a case of aVR ST-elevation myocardial infarction followed by wi
Externí odkaz:
https://doaj.org/article/151f5c44742140d18652e5a85e06a88c
Autor:
Christopher Clark, Mehdi Gholam, Leonardo Zullo, Anja Kerksiek, Enrique Castelao, Armin von Gunten, Martin Preisig, Dieter Lütjohann, Julius Popp
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106740- (2023)
Summary: Dysregulations in cholesterol metabolism are associated with neurodegenerative and vascular pathologies, and dementia. Diet-derived plant sterols (phytosterols) have cholesterol-lowering, anti-inflammatory, and antioxidant properties and may
Externí odkaz:
https://doaj.org/article/0af2c3be12fb4d51ace2f4d09437cedc
Publikováno v:
Digital Health, Vol 9 (2023)
Objective Our goal is to establish the feasibility of using an artificially intelligent chatbot in diverse healthcare settings to promote COVID-19 vaccination. Methods We designed an artificially intelligent chatbot deployed via short message service
Externí odkaz:
https://doaj.org/article/a7e0b8c7c98146d681d4c62d321cf794