Výsledky vyhledávání - "Christopher, Butler"

Akademický článek

The importance of appropriate selection of clinical endpoints in outpatient COVID-19 clinical trials

Autor: Kristian Thorlund, Davey Smith, Christopher Linsell, Nicholas White, Christopher Butler, David Boulware, Judith Currier, Ofir Harari, Edouard Lhomme, Nathalie Strub-Wourgaft, Stacey Adam, Edward Mills

Publikováno v: Communications Medicine, Vol 3, Iss 1, Pp 1-5 (2023)

Abstract Clinical trial endpoints must be carefully and intentionally selected so that the results of the trial can be used to inform policy- and decision-making. The relative importance of potential endpoints often depends on the stakeholder, with p

Externí odkaz: https://doaj.org/article/66d021901bcc41f9a3dde635bf62b6b8

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Akademický článek

Three-layer model with absorption for conservative estimation of the maximum acoustic transmission coefficient through the human skull for transcranial ultrasound stimulation

Autor: David Attali, Thomas Tiennot, Mark Schafer, Elsa Fouragnan, Jérôme Sallet, Charles F Caskey, Robert Chen, Ghazaleh Darmani, Ellen J. Bubrick, Christopher Butler, Charlotte J Stagg, Miriam Klein-Flügge, Lennart Verhagen, Seung-Schik Yoo, Kim Butts Pauly, Jean-Francois Aubry

Publikováno v: Brain Stimulation, Vol 16, Iss 1, Pp 48-55 (2023)

Transcranial ultrasound stimulation (TUS) has been shown to be a safe and effective technique for non-invasive superficial and deep brain stimulation. Safe and efficient translation to humans requires estimating the acoustic attenuation of the human

Externí odkaz: https://doaj.org/article/e778acb9f9984fd28e26ffb03664e83e

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Akademický článek

Correction: Development and evaluation of rapid data-enabled access to routine clinical information to enhance early recruitment to the national clinical platform trial of COVID-19 community treatments

Autor: Caroline Cake, Emma Ogburn, Heather Pinches, Garry Coleman, David Seymour, Fran Woodard, Sinduja Manohar, Marjia Monsur, Martin Landray, Gaynor Dalton, Andrew D. Morris, Patrick F. Chinnery, UK COVID-19 National Core Studies Consortium, F. D. Richard Hobbs, Christopher Butler

Publikováno v: Trials, Vol 24, Iss 1, Pp 1-1 (2023)

Externí odkaz: https://doaj.org/article/b0f5dee199ec4aad8d6a30d0a72a2d5e

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Akademický článek

Development and evaluation of rapid data-enabled access to routine clinical information to enhance early recruitment to the national clinical platform trial of COVID-19 community treatments

Publikováno v: Trials, Vol 23, Iss 1, Pp 1-10 (2022)

Abstract Background The COVID-19 pandemic has presented unique challenges for rapidly designing, initiating, and delivering therapeutic clinical trials. PRINCIPLE (Platform Randomised Trial of Treatments in the Community for Epidemic and Pandemic Ill

Externí odkaz: https://doaj.org/article/d49086dbe42b4ead8559dfb50ae69801

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Akademický článek

Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)

Respiratory syncytial virus (RSV) is a common infection in children and older adults but little is known about within-host viral population diversity. Here, the authors perform deep sequencing and find that RSV subgroup B exhibited more diversity tha

Externí odkaz: https://doaj.org/article/be54b219fed94f08b8ef4d94b0391eab

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Akademický článek

Managing Penicillin Allergy in Primary Care: An Important but Neglected Aspect of Antibiotic Stewardship

Autor: Marta Wanat, Sibyl Anthierens, Marta Santillo, Catherine Porter, Joanne Fielding, Mina Davoudianfar, Emily Bongard, Ly-Mee Yu, Christopher Butler, Louise Savic, Sinisa Savic, Johanna Cook, Kelsey Armitage, Philip Howard, Sue Pavitt, Jonathan A. T. Sandoe, Sarah Tonkin-Crine

Publikováno v: Medical Sciences Forum, Vol 15, Iss 1, p 8 (2023)

An estimated 2.7 million people in the UK are potentially prevented from accessing highly effective and inexpensive penicillins as a result of incorrect penicillin allergy records. Removing incorrect penicillin allergy records may lead to improved pa

Externí odkaz: https://doaj.org/article/8e8e6421ad014e9b8448974f126ae35f

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Akademický článek

Pelargonium sidoides root extract for the treatment of acute cough due to lower respiratory tract infection in adults: a feasibility double-blind, placebo-controlled randomised trial

Publikováno v: BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-16 (2021)

Abstract Background Pelargonium sidoides DC (Geraniaceae) root extract, EPs®7630 or “Kaloba®”, is a widely used herbal remedy for respiratory infections, with some evidence of effectiveness for acute bronchitis. However, it is not yet widely re

Externí odkaz: https://doaj.org/article/ac120b8311764d5ca70b7034e3694d87

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Akademický článek

Health economic modeling for Alzheimer's disease: Expert perspectives

Autor: Filipa Landeiro, Jasmine Morton, Anders Gustavsson, Michele Potashman, Pascal Lecomte, Mark Belger, Robin Thompson, Emilse Roncancio‐Diaz, Gurleen Jhuti, Christopher Butler, Linus Jönsson, Ron Handels, Alastair M. Gray, the ROADMAP study

Publikováno v: Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)

Abstract The successful development of an economic model for the evaluation of future Alzheimer's disease (AD) interventions is critical to accurately inform policy makers and payers. As our understanding of AD expands, this becomes an increasingly c

Externí odkaz: https://doaj.org/article/8b096dbb28a34191a377db2b6db52ed4

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