Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Christophe Sirac"'
Autor:
Natsuko Ueda, Marine Cahen, Jenny Leonard, Laurent Deleurme, Stéphane Dreano, Christophe Sirac, Anne Galy, Jérôme Moreaux, Yannic Danger, Michel Cogné
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract T-cell-based adoptive immunotherapy is a new pillar of cancer care. Tumor-redirected B cells could also contribute to therapy if their manipulation to rewire immunoglobulin (Ig) genes is mastered. We designed a single-chain Ig-encoding casse
Externí odkaz:
https://doaj.org/article/d68373b8483948dca616dd429ddf3831
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Monoclonal immunoglobulin (Ig) light chain amyloidosis (AL) is a rare but severe disease that may occur when a B or plasma cell clone secretes an excess of free Ig light chains (LCs). Some of these LCs tend to aggregate into organized fibrils with a
Externí odkaz:
https://doaj.org/article/fd5fc1cb31d044fa97d271a5c6cf1fa7
Autor:
Sandrine Le Noir, Amélie Bonaud, Bastien Hervé, Audrey Baylet, François Boyer, Sandrine Lecardeur, Zeliha Oruc, Christophe Sirac, Michel Cogné
Publikováno v:
PLoS Genetics, Vol 17, Iss 2, p e1009288 (2021)
DNA lesions inflicted by activation-induced deaminase (AID) instrumentally initiate the processes reshaping immunoglobulin genes in mature B-cells, from local somatic hypermutation (SHM) to junctions of distant breaks during class switch recombinatio
Externí odkaz:
https://doaj.org/article/7b7de61c0ffa40279b78ce35036b14bf
Autor:
Sébastien Bender, Maria Victoria Ayala, Vincent Javaugue, Amélie Bonaud, Michel Cogné, Guy Touchard, Arnaud Jaccard, Frank Bridoux, Christophe Sirac
Publikováno v:
Haematologica, Vol 103, Iss 11 (2018)
Externí odkaz:
https://doaj.org/article/2e139dbac2514062848bc315026993d4
Autor:
Camille Cohen, Florent Joly, Audrey Sibille, Vincent Javaugue, Estelle Desport, Jean-Michel Goujon, Guy Touchard, Jean-Paul Fermand, Christophe Sirac, Frank Bridoux
Publikováno v:
Diagnostics, Vol 11, Iss 3, p 420 (2021)
Randall-type monoclonal immunoglobulin deposition disease (MIDD) is a rare disease that belongs to the spectrum of monoclonal gammopathy of renal significance (MGRS). Renal involvement is prominent in MIDD, but extra-renal manifestations can be prese
Externí odkaz:
https://doaj.org/article/48843799de3b4089aa06b0c245abb268
Autor:
Thomas D. Barbour, Piers Blombery, Guy Touchard, Christophe Sirac, Lucy C. Fox, Moira Finlay, Adam G. Steinberg, Ahida Batrouney, Sébastien Bender, Surender Juneja, Frank Bridoux
Publikováno v:
American Journal of Kidney Diseases. 78:459-463
There is increasing recognition of monoclonal gammopathy as a cause of proliferative glomerulonephritis (GN), including cases in which glomerular deposition of monoclonal immunoglobulin is demonstrated. Recently, proliferative GN with monoclonal immu
Autor:
Samih H. Nasr, Satoru Kudose, Vincent Javaugue, Stéphanie Harel, Samar M. Said, Virginie Pascal, M. Barry Stokes, Julie A. Vrana, Surendra Dasari, Jason D. Theis, George A. Osuchukwu, Insara Jaffer Sathick, Arjun Das, Ali Kashkouli, Elliot J. Suchin, Yaakov Liss, Zalman Suldan, Jerome Verine, Bertrand Arnulf, Alexis Talbot, Sanjeev Sethi, Mohamad Zaidan, Jean-Michel Goujon, Anthony M. Valeri, Ellen D. Mcphail, Christophe Sirac, Nelson Leung, Frank Bridoux, Vivette D. D’Agati
Publikováno v:
Kidney international.
Monoclonal immunoglobulin light chain (LC) crystalline inclusions within podocytes is a rare, poorly characterized entity. To provide more insight, we now present the first clinicopathologic series of LC crystalline podocytopathy (LCCP) encompassing
Autor:
Natsuko Ueda, Marine Cahen, Christophe Sirac, Anne Galy, Jérôme Moreaux, Yannic Danger, Michel Cogné
Lymphocytes have become attractive agents for adoptive immunotherapy but only the reformatting of T cells is efficiently mastered. Despite some recent breakthroughs, B cells remain challenging targets, with regard to both their long-term survival aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::432224c7e16356fd3e043dbab304316a
https://doi.org/10.1101/2022.06.02.494471
https://doi.org/10.1101/2022.06.02.494471
Autor:
Lynn D. Cornell, Julie A. Vrana, Thomas Guincestre, Nelson Leung, Surendra Dasari, Christophe Sirac, Ziad A. Massy, Christopher P. Larsen, David Buob, Sophie Chauvet, Ellen D. McPhail, Vincent Javaugue, Samih H. Nasr, Eve Vilaine, Frank Bridoux, Vivette D. D'Agati, Guy Touchard, Samar M. Said, Jean Jacques Boffa, Jonathan J. Hogan, Stéphanie Toussaint, Camille Domenger, Jason D. Theis
Publikováno v:
Kidney International. 97:589-601
IgG (mainly IgG3) is the most commonly involved isotype in proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID). Here we describe the first series of PGNMID with deposition of monoclonal immunoglobulin light chain only (P
Autor:
Alexis Saintamand, Frank Bridoux, Sarah Nasraddine, Mathilde Dargelos, Michel Cogné, Estelle Desport, Sabrina Bouyer, Mehdi Alizadeh, Vincent Javaugue, Paco Derouault, Sébastien Bender, Matthieu Filloux, Virginie Pascal, Christophe Sirac, Arnaud Jaccard
Publikováno v:
Kidney International
Kidney International, Nature Publishing Group, 2021, ⟨10.1016/j.kint.2021.10.017⟩
Kidney International, 2022, 101 (2), pp.331-337. ⟨10.1016/j.kint.2021.10.017⟩
Kidney International, Nature Publishing Group, 2021, ⟨10.1016/j.kint.2021.10.017⟩
Kidney International, 2022, 101 (2), pp.331-337. ⟨10.1016/j.kint.2021.10.017⟩
International audience; The diagnostic approach of monoclonal gammopathy of renal significance is based on the detection of a monoclonal immunoglobulin in the blood and urine, and the identification of the underlying clone through bone marrow and/or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb1b775226d5690c2ee8cf44fa1ba01
https://hal.archives-ouvertes.fr/hal-03482172
https://hal.archives-ouvertes.fr/hal-03482172