Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Christophe Simard"'
Autor:
Samuel Deshayes, Caroline Baugé, Pierre-Antoine Dupont, Christophe Simard, Hanan Rida, Hubert de Boysson, Alain Manrique, Achille Aouba
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Background Metabolic imaging is routinely used to demonstrate aortitis in patients with giant-cell arteritis. We aimed to investigate the preclinical model of aortitis in BALB/c IL1rn −/− mice using [18F]fluorodeoxyglucose ([18F]FDG) pos
Externí odkaz:
https://doaj.org/article/d276c07982574a809b5befddbacffad9
Autor:
Christophe Simard, Margaux Aize, Sébastien Chaigne, Harlyne Mpweme Bangando, Romain Guinamard
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5860 (2023)
The role of ion channels is extensively described in the context of the electrical activity of excitable cells and in excitation-contraction coupling. They are, through this phenomenon, a key element for cardiac activity and its dysfunction. They als
Externí odkaz:
https://doaj.org/article/9e8e111a04d042c2a69e5f395887ee5b
Autor:
Christophe Simard, Virginie Ferchaud, Laurent Sallé, Paul Milliez, Alain Manrique, Joachim Alexandre, Romain Guinamard
Publikováno v:
Cells, Vol 10, Iss 3, p 636 (2021)
Aldosterone plays a major role in atrial structural and electrical remodeling, in particular through Ca2+-transient perturbations and shortening of the action potential. The Ca2+-activated non-selective cation channel Transient Receptor Potential Mel
Externí odkaz:
https://doaj.org/article/3caa3e296ff7494da33fc47b2312f3a9
Autor:
Hui Liu, Stéphanie Chatel, Christophe Simard, Ninda Syam, Laurent Salle, Vincent Probst, Julie Morel, Gilles Millat, Michel Lopez, Hugues Abriel, Jean-Jacques Schott, Romain Guinamard, Patrice Bouvagnet
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54131 (2013)
Brugada syndrome (BrS) is a condition defined by ST-segment alteration in right precordial leads and a risk of sudden death. Because BrS is often associated with right bundle branch block and the TRPM4 gene is involved in conduction blocks, we screen
Externí odkaz:
https://doaj.org/article/8c664dfcc2d54849bed4c4b23a727a01
Autor:
Alexandre Fouchet, Harlyne Mpweme Bangando, Margaux Aize, Christophe Simard, Romain Guinamard
Publikováno v:
Reproduction.
Control of uterine contractions is of interest in the context of inappropriate myometrial activity during pregnancy and at time of delivery but it is also a matter for menstrual pain. While several molecular determinants of myometrial contractions ha
Autor:
Margaux Aize, Harlyne Mpweme Bangando, Laura Brard, Arthur Boileve, Vladimir Saplacan, Alexandre Lebrun, Nicolas Perzo, Alain Manrique, Romain Guinamard, Christophe Simard
Publikováno v:
Archives of Cardiovascular Diseases Supplements. 15:219-220
Autor:
Investigators, Harlyne Mpweme Bangando, Christophe Simard, Margaux Aize, Alexandre Lebrun, Alain Manrique, Romain Guinamard, on behalf of the STOP-AS Investigators on behalf of the STOP-AS
Publikováno v:
Cancers; Volume 14; Issue 18; Pages: 4477
Thoracic radiotherapy can lead to cardiac remodeling including valvular stenosis due to fibrosis and calcification. The monovalent non-selective cation channel TRPM4 is known to be involved in calcium handling and to participate in fibroblast transit
Autor:
Harlyne, Mpweme Bangando, Christophe, Simard, Margaux, Aize, Alexandre, Lebrun, Alain, Manrique, Romain, Guinamard, On Behalf Of The Stop-As Investigators
Publikováno v:
Cancers. 14(18)
Thoracic radiotherapy can lead to cardiac remodeling including valvular stenosis due to fibrosis and calcification. The monovalent non-selective cation channel TRPM4 is known to be involved in calcium handling and to participate in fibroblast transit
Autor:
Racim Adjlane, Alain Manrique, Christophe Magaud, Christophe Simard, Romain Guinamard, Laurent Sallé, Patrick Bois, Quentin Dupas, Jean-François Faivre
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 472:1719-1732
Cardiac fibroblasts play an important role in cardiac matrix turnover and are involved in cardiac fibrosis development. Ca2+ is a driving belt in this phenomenon. This study evaluates the functional expression and contribution of the Ca2+-activated c
Autor:
Margaux Aize, Harlyne Mpweme Bangando, Laura Brard, Nicolas Perzo, Romain Guinamard, Christophe Simard
Publikováno v:
Archives of Cardiovascular Diseases Supplements. 14:200