Výsledky vyhledávání - "Christophe Roberge"

Akademický článek

Proof-of-concept study for a long-acting formulation of ivermectin injected in cattle as a complementary malaria vector control tool

Autor: Sié Hermann Pooda, Nicolas Moiroux, Angélique Porciani, Anne-Laure Courjaud, Christophe Roberge, Georges Gaudriault, Issa Sidibé, Adrien Marie Gaston Belem, Jean-Baptiste Rayaissé, Roch K. Dabiré, Karine Mouline

Publikováno v: Parasites & Vectors, Vol 16, Iss 1, Pp 1-12 (2023)

Abstract Background Domesticated animals play a role in maintaining residual transmission of Plasmodium parasites of humans, by offering alternative blood meal sources for malaria vectors to survive on. However, the blood of animals treated with vete

Externí odkaz: https://doaj.org/article/521fda24d64a432186b2822ed829a76c

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BEPO®: Bioresorbable diblock mPEG-PDLLA and triblock PDLLA-PEG-PDLLA based in situ forming depots with flexible drug delivery kinetics modulation

Autor: Pierre Berto, Joël Richard, Jean-Manuel Cros, Tjasa Vrlinic, Adolfo López-Noriega, Marie-Emérentienne Cagnon, Christophe Roberge, Juliette Serindoux, Rémi Samuel, Anthony Rech

Publikováno v: Journal of Controlled Release. 319:416-427

This article presents BEPO®, an in situ forming depot (ISFD) technology mediated by a solvent-exchange mechanism. The matrix of the in situ formed drug delivery depot is composed of the combination of a diblock (DB) and a triblock (TB) polyethylene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3837cc4db943c45d960908db06f60901
https://doi.org/10.1016/j.jconrel.2020.01.022

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A Six-Months, Long Acting, One-Shot Injectable Formulation of Ivermectin as a Complementary Malaria Vector Control Tool to Target Zoophagic Anopheles: Laboratory and Model-Based Proofs of Concept

Autor: Sié Hermann Pooda, Nicolas Moiroux, Angélique Porciani, Anne-Laure Courgeault, Christophe Roberge, Georges Gaudriault, Issa Sidibé, Adrien Marie Gaston Belem, Jean-Baptiste Rayaissé, Roch K. Dabiré, Karine Mouline

Publikováno v: SSRN Electronic Journal.

SummaryContextIn the current context of residual plasmodium transmission where zoophagic proclivities of Anopheles intervene, we propose to treat peridomestic animals using the endectocide Ivermectin as a complementary approach to bednets. As Ivermec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2180946bdd3227b171b3aaa8dca13472
https://doi.org/10.2139/ssrn.4088191

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Effects of an injectable long-acting formulation of ivermectin on Onchocerca ochengi in zebu cattle

Autor: Sébastien D Pion, Christophe Roberge, Peter Enyong, Samuel Wanji, Georges Gaudriault, Patrick W. Chounna-Ndongmo, Abdel-Jelil Njouendou, Anthony Rech, Michel Boussinesq

Publikováno v: Parasite
Parasite, EDP Sciences, 2020, 27, pp.36. ⟨10.1051/parasite/2020036⟩
Parasite, Vol 27, p 36 (2020)

The availability of a safe macrofilaricidal drug would help to accelerate onchocerciasis elimination. A trial was conducted in Cameroon to evaluate the effects of a subcutaneous injectable long-acting formulation of ivermectin (LAFI) on the microfila

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e85b4b98ca36fa65c027f5dd8cfa6eb
http://www.documentation.ird.fr/hor/fdi:010078125

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Evaluation of Loco-Regional Skin Toxicity Induced by an In Situ Forming Depot after a Single Subcutaneous Injection at Different Volumes and Flow Rates in Göttingen Minipigs

Autor: Adolfo López-Noriega, Anne-Pascale Trichet, Jacques Descotes, Charlotte Peloso, Christophe Roberge, Joël Richard

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 9250, p 9250 (2021)
Volume 22
Issue 17

The present study aims to investigate the loco-regional tolerability and injection parameters (i.e., flow rate and administration volume) of an in situ forming depot (ISFD) in Göttingen minipigs, to secure both the therapeutic procedure and complian

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8ffcf159a6efb742f0f1dce49851a36
https://doi.org/10.3390/ijms22179250

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Solid emulsion gel as a novel construct for topical applications: synthesis, morphology and mechanical properties

Autor: Christophe Roberge, Marielle Robert, Kirill Shingel, Jolanta E. Klemberg-Sapieha, Oleg Zabeida

Publikováno v: Journal of Materials Science: Materials in Medicine. 20:681-689

A series of the solid emulsion gels with the oil volume fraction in the range of 0-50% were synthesized through a polycondensation reaction between activated p-nitrophenyl carbonate poly(ethylene glycol) and protein-stabilized oil-in-water emulsions.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37cb357757d06c7cc99db2ca03e1007b
https://doi.org/10.1007/s10856-008-3613-0

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Solid emulsion gel as a vehicle for delivery of polyunsaturated fatty acids: implications for tissue repair, dermal angiogenesis and wound healing

Autor: Laurent Azoulay, Christophe Roberge, Marie-Pierre Faure, Kirill Shingel, Richard J. Deckelbaum

Publikováno v: Journal of Tissue Engineering and Regenerative Medicine. 2:383-393

The paper describes preparation and biological characterization of the solid hybrid biomaterial that was designed for cell-targeted lipid delivery in healing tissues. The material referred to as 'solid emulsion gel' combines a protein-stabilized lipi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9c6346e4aaf376a0e9d50687bbee9a
https://doi.org/10.1002/term.101

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Electrically Conductive Biodegradable Polymer Composite for Nerve Regeneration: Electricity-Stimulated Neurite Outgrowth and Axon Regeneration

Autor: Jiangming Li, Lê H. Dao, Phillippe Roche, Christophe Roberge, Guixin Shi, Mahmoud Rouabhia, Zhaoxu Wang, Ze Zhang

Publikováno v: Artificial Organs. 31:13-22

Normal and electrically stimulated PC12 cell cultures and the implantation of nerve guidance channels were performed to evaluate newly developed electrically conductive biodegradable polymer composites. Polypyrrole (PPy) doped by butane sulfonic acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc327e920fbb78d8ee4156645f5efe1
https://doi.org/10.1111/j.1525-1594.2007.00335.x

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A biodegradable electrical bioconductor made of polypyrrole nanoparticle/poly(D,L-lactide) composite: A preliminaryin vitro biostability study

Autor: Zhaoxu Wang, Lê H. Dao, Ze Zhang, Christophe Roberge, Robert Guidoin, Ying Wan

Publikováno v: Journal of Biomedical Materials Research. :738-746

The electrical stability of a novel polypyrrole (PPy)/poly(D,L-lactide) (PDLLA) composite was studied in vitro and compared with that of PPy-coated polyester fabrics. Specimens were incubated in Ringer's solution at 37°C for up to 8 weeks with or wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943c0a68e74c94b14dc3ef719b521160
https://doi.org/10.1002/jbm.a.10037

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