Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Christophe Pellefigues"'
Autor:
John TCHEN, Quentin SIMON, Léa CHAPART, Morgane K. THAMINY, Shamila VIBHUSHAN, Loredana SAVEANU, Yasmine LAMRI, Fanny SAIDOUNE, Emeline PACREAU, Christophe PELLEFIGUES, Julie BEX-COUDRAT, Hajime KARASUYAMA, Kensuke MIYAKE, Juan HIDALGO, Padraic G. FALLON, Thomas PAPO, Ulrich BLANK, Marc BENHAMOU, Guillaume HANOUNA, Karim SACRE, Eric DAUGAS, Nicolas CHARLES
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by anti-nuclear autoantibodies whose production is promoted by autoreactive T follicular helper (TFH) cells. During SLE pathogenesis, basophils accumulate in secondary
Externí odkaz:
https://doaj.org/article/2b261c12033c4401a2b53ad4f143bfa7
Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/60aa48ef55f2494a93bf0529bb49a2d4
Autor:
John Tchen, Quentin Simon, Léa Chapart, Christophe Pellefigues, Hajime Karasuyama, Kensuke Miyake, Ulrich Blank, Marc Benhamou, Eric Daugas, Nicolas Charles
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tissue-specific mouse models are essential tools to decipher the role of each cell compartment and/or their expressed genes in the pathophysiology of diseases. Here, we describe a new knock-in mouse model allowing expression of both the fluorescent p
Externí odkaz:
https://doaj.org/article/6d84a6fd725646d891b31d23a059b29f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Systemic lupus erythematosus is a complex autoimmune disease during which patients develop autoantibodies raised against nuclear antigens. During the course of the disease, by accumulating in secondary lymphoid organs (SLOs), basophils support autore
Externí odkaz:
https://doaj.org/article/385df604c19b4f3489d0325aa240165e
Autor:
Kara J. Filbey, Palak H. Mehta, Kimberley J. Meijlink, Christophe Pellefigues, Alfonso J. Schmidt, Graham Le Gros
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Helminths regulate host immune responses to ensure their own long-term survival. Numerous studies have demonstrated that these helminth-induced regulatory mechanisms can also limit host inflammatory responses in several disease models. We used the He
Externí odkaz:
https://doaj.org/article/b65568ea2c09443eb87a1ac156163551
Autor:
Christophe Pellefigues, Barbara Dema, Yasmine Lamri, Fanny Saidoune, Nathalie Chavarot, Charlotte Lohéac, Emeline Pacreau, Michael Dussiot, Caroline Bidault, Florian Marquet, Mathieu Jablonski, Jonathan M. Chemouny, Fanny Jouan, Antoine Dossier, Marie-Paule Chauveheid, Delphine Gobert, Thomas Papo, Hajime Karasuyama, Karim Sacré, Eric Daugas, Nicolas Charles
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
In a lupus environment, basophils accumulate in secondary lymphoid organs where they affect pathogenesis by stimulating autoantibody production. Here the authors show this accumulation is driven by PGD2-induced CXCR4 surface expression and traffickin
Externí odkaz:
https://doaj.org/article/80954cdc9d4244429cf721f1490b4ce5
Autor:
Barbara Dema, Yasmine Lamri, Christophe Pellefigues, Emeline Pacreau, Fanny Saidoune, Caroline Bidault, Hajime Karasuyama, Karim Sacré, Eric Daugas, Nicolas Charles
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Lupus nephritis (LN), one of the most severe outcomes of systemic lupus erythematosus (SLE), is initiated by glomerular deposition of immune-complexes leading to an inflammatory response and kidney failure. Autoantibodies to nuclear antigens
Externí odkaz:
https://doaj.org/article/d1e831bfa8914cf4b9b64614988ae423
Autor:
Christophe Pellefigues, Palak Mehta, Melanie Sarah Prout, Karmella Naidoo, Bibek Yumnam, Jodie Chandler, Sally Chappell, Kara Filbey, Mali Camberis, Graham Le Gros
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Basophils are granulocytes involved in parasite immunity and allergic diseases, known for their potent secretion of type 2 cytokines. Identifying their functions has proven to be controversial due to their relative rarity and their complex lineage ph
Externí odkaz:
https://doaj.org/article/4f9755fc5097464a9ad630d364947b4c
Autor:
Palak Mehta, Jodie Chandler, Christophe Pellefigues, Karmella Naidoo, Mali Camberis, Bibek Yumnam, Melanie Prout, Graham Le Gros, Sally Chappell, Kara J. Filbey
Publikováno v:
Pellefigues, C, Mehta, P, Naidoo, K, Yumnam, B, Chandler, J, Chappell, S, Filbey, K, Camberis, M & Le Gros, G 2019, ' The Basoph8 mice enable an unbiased detection and a conditional depletion of basophils. ', Frontiers in Immunology, vol. 10 . https://doi.org/10.3389/fimmu.2019.02143
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Basophils are granulocytes involved in parasite immunity and allergic diseases, known for their potent secretion of type 2 cytokines. Identifying their functions has proven to be controversial due to their relative rarity and their complex lineage ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5648bf1ee84303306e7f39249102ce
https://ora.ox.ac.uk/objects/uuid:fdc1f43e-65b0-464e-b58b-6e55ae876979
https://ora.ox.ac.uk/objects/uuid:fdc1f43e-65b0-464e-b58b-6e55ae876979
