Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Christophe Papin"'
Autor:
Christophe Papin, Abdulkhaleg Ibrahim, Jamal S. M. Sabir, Stéphanie Le Gras, Isabelle Stoll, Raed S. Albiheyri, Ali T. Zari, Ahmed Bahieldin, Alfonso Bellacosa, Christian Bronner, Ali Hamiche
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-19 (2023)
Abstract Background Inherited defects in the base-excision repair gene MBD4 predispose individuals to adenomatous polyposis and colorectal cancer, which is characterized by an accumulation of C > T transitions resulting from spontaneous deamination o
Externí odkaz:
https://doaj.org/article/5389b4aa773a4bfe8eefdf04a989867d
Autor:
John Lalith Charles Richard, Manu Shubhdarshan Shukla, Hervé Menoni, Khalid Ouararhni, Imtiaz Nisar Lone, Yohan Roulland, Christophe Papin, Elsa Ben Simon, Tapas Kundu, Ali Hamiche, Dimitar Angelov, Stefan Dimitrov
Publikováno v:
PLoS Genetics, Vol 12, Iss 7, p e1006221 (2016)
FACT, in addition to its role in transcription, is likely implicated in both transcription-coupled nucleotide excision repair and DNA double strand break repair. Here, we present evidence that FACT could be directly involved in Base Excision Repair a
Externí odkaz:
https://doaj.org/article/b6f82e8a391748f8a4fccef8bb2f35cb
Autor:
Emeline Fontaine, Christophe Papin, Guillaume Martinez, Stéphanie Le Gras, Roland Abi Nahed, Patrick Héry, Thierry Buchou, Khalid Ouararhni, Bertrand Favier, Thierry Gautier, Jamal S M Sabir, Matthieu Gerard, Jan Bednar, Christophe Arnoult, Stefan Dimitrov, Ali Hamiche
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2022, 50 (13), pp.7350-7366. ⟨10.1093/nar/gkac541⟩
Nucleic Acids Research, 2022, 50 (13), pp.7350-7366. ⟨10.1093/nar/gkac541⟩
The histone variant H3.3 is encoded by two distinct genes, H3f3a and H3f3b, exhibiting identical amino-acid sequence. H3.3 is required for spermatogenesis, but the molecular mechanism of its spermatogenic function remains obscure. Here, we have studi
Autor:
Christophe Papin, Kareem Mohideen-Abdul, Stephanie Gras, Ali Hamiche, Bruno P. Klaholz, Stefan Dimitrov, Isabelle Stoll, Christian Bronner, Abdulkhaleg Ibrahim
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2021, 372 (6549), ⟨10.1126/science.abd5581⟩
Science, 2021, 372 (6549), ⟨10.1126/science.abd5581⟩
Science, American Association for the Advancement of Science, 2021, 372 (6549), ⟨10.1126/science.abd5581⟩
Science, 2021, 372 (6549), ⟨10.1126/science.abd5581⟩
MeCP2 binds hydroxymethylated CA repeats Despites of decades of research on the Rett syndrome protein MeCP2, its function remains unclear. Ibrahim et al. show that MeCP2 is a hydroxymethylated cytosine-adenosine (CA) repeat-binding protein that modul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa2495985bc907c9bcd81e26ff66f2a
https://www.hal.inserm.fr/inserm-03376640
https://www.hal.inserm.fr/inserm-03376640
Autor:
Kiran Padmanabhan, Ali Hamiche, Stefan Dimitrov, Lorrie Ramos, Christophe Papin, Defne Dalkara, Yann-Gaël Gangloff, Nicolas Lacoste, Isabella Scionti, Laurent Schaeffer, Edwige Belotti, Thomas Simonet
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2020, 48, pp.4601-4613. ⟨10.1093/nar/gkaa157⟩
Nucleic Acids Research, Oxford University Press, 2020, 48 (9), pp.4601-4613. ⟨10.1093/nar/gkaa157⟩
Nucleic Acids Research, 2020, 48 (9), pp.4601-4613. ⟨10.1093/nar/gkaa157⟩
Nucleic Acids Research, Oxford University Press, 2020, 48, pp.4601-4613. ⟨10.1093/nar/gkaa157⟩
Nucleic Acids Research, Oxford University Press, 2020, 48 (9), pp.4601-4613. ⟨10.1093/nar/gkaa157⟩
Nucleic Acids Research, 2020, 48 (9), pp.4601-4613. ⟨10.1093/nar/gkaa157⟩
While the histone variant H2A.Z is known to be required for mitosis, it is also enriched in nucleosomes surrounding the transcription start site of active promoters, implicating H2A.Z in transcription. However, evidence obtained so far mainly rely on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30b351fbc8d2bed8599301df8df7928
https://avesis.deu.edu.tr/publication/details/0ffef56b-2c9f-4f12-82bb-0b9bd2ad8259/oai
https://avesis.deu.edu.tr/publication/details/0ffef56b-2c9f-4f12-82bb-0b9bd2ad8259/oai
Autor:
Aysegul Ors, Stefan Dimitrov, Bertrand Favier, Ali Hamiche, Defne Dalkara, Mehmet Ozturk, Yohan Roulland, Kiran Padmanabhan, Christophe Papin
Publikováno v:
Biochemistry and Cell Biology
Biochemistry and Cell Biology, NRC Research Press, 2017, 95 (4), pp.491-499. ⟨10.1139/bcb-2016-0190⟩
Biochemistry and Cell Biology, NRC Research Press, 2017, 95 (4), pp.491-499. ⟨10.1139/bcb-2016-0190⟩
H3.3 is a histone variant that marks transcription start sites as well as telomeres and heterochromatic sites on the genome. The presence of H3.3 is thought to positively correlate with the transcriptional status of its target genes. Using a conditio
Autor:
Waseem Ashraf, Christian Bronner, Abdulkhaleg Ibrahim, Christophe Papin, Mahmoud Alhosin, Liliyana Zaayter, Khalid Ouararhni, Tanveer Ahmad, Yves Mély, Marc Mousli, Ali Hamiche
Publikováno v:
Oncotarget
Oncotarget, Impact journals, 2017, 8 (31), pp.51946-51962. ⟨10.18632/oncotarget.17393⟩
Oncotarget, Impact journals, 2017, 8 (31), pp.51946-51962. ⟨10.18632/oncotarget.17393⟩
// Waseem Ashraf 1 , Abdulkhaleg Ibrahim 2 , Mahmoud Alhosin 3,4,5 , Liliyana Zaayter 1 , Khalid Ouararhni 2 , Christophe Papin 2 , Tanveer Ahmad 1 , Ali Hamiche 2 , Yves Mely 1 , Christian Bronner 2,* and Marc Mousli 1,* 1 Laboratory of Biophotonics
Autor:
Thomas Simonet, Kiran Padmanabhan, Defne Dalkara, Ali Hamiche, Stefan Dimitrov, Nicolas Lacoste, Laurent Schaeffer, Edwige Belotti, Isabella Scionti, Lorrie Ramos, Christophe Papin
The histone variant H2A.Z is enriched in nucleosomes surrounding the transcription start site of active promoters, suggesting that it might be implicated in transcription. It is also required during mitosis. However, evidences obtained so far mainly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19eca95cc5b72634f6fec120cd483310
https://doi.org/10.1101/823526
https://doi.org/10.1101/823526
Autor:
Ziad Omran, Isabelle Stoll, Iva Ugrinova, Abdulkhaleg Ibrahim, Mohammad M. Karimi, Ali Hamiche, Christian Bronner, Maria Schröder, Christophe Papin, Hatem Salem, Stéphanie Le Gras, Emeline Fontaine-Pelletier, Stefan Dimitrov
Publikováno v:
Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2021, 433 (6), pp.166659. ⟨10.1016/j.jmb.2020.09.018⟩
Journal of Molecular Biology, Elsevier, 2021, 433 (6), pp.166659. ⟨10.1016/j.jmb.2020.09.018⟩
International audience; Epigenetic modifications and nucleosome positioning play an important role in modulating gene expression. However, how the patterns of epigenetic modifications and nucleosome positioning are established around promoters is not
Publikováno v:
Neuro-Oncology
Pediatric high-grade gliomas (pHGGs) have a very dismal prognosis and need new innovative strategy for treatment. Despite the past discovery of histone H3 driver mutations, we are not able for instance to stop this induced epigenetic remodulation. Th