Efficient synthesis of both diastereomers of β,γ-diamino acids from phenylalanine and tryptophan

Autor: Régis Guillot, Sylvain Cote des Combes, Christophe Pacaud, Nicolas Auberger, Sophie Thétiot-Laurent, Ingrid Devillers, Valérie Alezra, Andrii Stanovych, Cyrille Kouklovsky

Publikováno v: Amino Acids
Amino Acids, 2016, 48 (9), pp.2237--2242. ⟨10.1007/s00726-016-2262-8⟩
Amino Acids, Springer Verlag, 2016, 48 (9), pp.2237--2242. ⟨10.1007/s00726-016-2262-8⟩

We synthesized in a few steps both diastereomers of orthogonally protected β,γ-diamino acids starting from L-phenylalanine or L-tryptophan. These final compounds are interesting building blocks for peptide synthesis and foldamer chemistry. The key

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b83cff81c384ed1334e3f5401029ce
https://pubmed.ncbi.nlm.nih.gov/27206723