Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Christophe Orvain"'
Autor:
Aina Venkatasamy, Eric Guerin, Anais Blanchet, Christophe Orvain, Véronique Devignot, Matthieu Jung, Alain C. Jung, Marie-Pierre Chenard, Benoit Romain, Christian Gaiddon, Georg Mellitzer
Publikováno v:
Pharmaceutics, Vol 13, Iss 9, p 1485 (2021)
The reasons behind the poor efficacy of transition metal-based chemotherapies (e.g., cisplatin) or targeted therapies (e.g., histone deacetylase inhibitors, HDACi) on gastric cancer (GC) remain elusive and recent studies suggested that the tumor micr
Externí odkaz:
https://doaj.org/article/bb3db2c261f34fae99f13ec7309f2986
Autor:
Maria Dalla Pozza, Christophe Orvain, Leonardo Brustolin, Nicolò Pettenuzzo, Chiara Nardon, Christian Gaiddon, Dolores Fregona
Publikováno v:
Molecules, Vol 26, Iss 13, p 4073 (2021)
Malignant tumors have affected the human being since the pharaoh period, but in the last century the incidence of this disease has increased due to a large number of risk factors, including deleterious lifestyle habits (i.e., smoking) and the higher
Externí odkaz:
https://doaj.org/article/939376302eae4ffbb2670cac01a8bc13
Autor:
Marie-Elodie Spaety, Alexandre Gries, Amandine Badie, Aina Venkatasamy, Benoit Romain, Christophe Orvain, Kazuyoshi Yanagihara, Koji Okamoto, Alain C. Jung, Georg Mellitzer, Sébastien Pfeffer, Christian Gaiddon
Publikováno v:
Cancers, Vol 11, Iss 11, p 1747 (2019)
Gastric cancer (GC) remains a health issue due to the low efficiency of therapies, such as cisplatin. This unsatisfactory situation highlights the necessity of finding factors impacting GC sensibility to therapies. We analyzed the cisplatin pangenomi
Externí odkaz:
https://doaj.org/article/938cfbcef38c493c992b336e6d9482f0
Autor:
Carolina Torres‐Gutiérrez, Aldo S. Estrada‐Montaño, Christophe Orvain, Georg Mellitzer, Christian Gaiddon, Ronan Le Lagadec
Publikováno v:
European Journal of Inorganic Chemistry.
Autor:
Jessica J. Miller, Kalvin Kwan, Anaïs Blanchet, Christophe Orvain, Georg Mellitzer, Jason Smith, Cristina Lento, Lucienne Nouchikian, Sabrina Omoregbee-Leichnitz, Marie Sabatou, Derek Wilson, Christian Gaiddon, Tim Storr
Publikováno v:
Journal of Inorganic Biochemistry. 242:112164
Autor:
Pierre MOBIAN, christian Gaiddon, cecchini marco, galentino katia, Matthieu scarpi-luttenauer, Christophe orvain
Publikováno v:
Inorganica Chimica Acta. 540:121036
Autor:
Jessica J. Miller, Tim Storr, Christophe Orvain, Anais Blanchet, Diego Martelino, Derek J. Wilson, Lucienne Nouchikian, Ryan M. Clarke, Yasmin Reviriot, Christian Gaiddon
Publikováno v:
Chemical Science
Chemical Science, The Royal Society of Chemistry, 2019, Epub ahead of print. ⟨10.1039/c9sc04151f⟩
Chemical Science, 2019, Epub ahead of print. ⟨10.1039/c9sc04151f⟩
Chemical Science, The Royal Society of Chemistry, 2019, Epub ahead of print. ⟨10.1039/c9sc04151f⟩
Chemical Science, 2019, Epub ahead of print. ⟨10.1039/c9sc04151f⟩
International audience; Protein misfolding and aggregation contributes to the development of a wide range of diseases. In cancer, over 50% of diagnoses are attributed to p53 malfunction due to missense mutations, many of which result in protein misfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7363bcdec92671d3aa0d33e9ebbe371c
https://www.hal.inserm.fr/inserm-02364138
https://www.hal.inserm.fr/inserm-02364138
Autor:
Shireen Jozi, Jason R. Smith, Ryan M. Clarke, Christian Gaiddon, Jeffrey J. Warren, Tim Storr, Jessica J. Miller, Anais Blanchet, Christophe Orvain
Publikováno v:
Chemistry-A European Journal
Chemistry-A European Journal, 2018, 24 (67), pp.17734-17742. ⟨10.1002/chem.201802677⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2018, 24 (67), pp.17734-17742. ⟨10.1002/chem.201802677⟩
Chemistry-A European Journal, 2018, 24 (67), pp.17734-17742. ⟨10.1002/chem.201802677⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2018, 24 (67), pp.17734-17742. ⟨10.1002/chem.201802677⟩
International audience; The p53 protein plays a major role in cancer prevention, and over 50 % of cancer diagnoses can be attributed to p53 malfunction. The common p53 mutation Y220C causes local protein unfolding, aggregation, and can result in a lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272afda3c0914f96547ca96b5aac60ec
http://summit.sfu.ca/item/19848
http://summit.sfu.ca/item/19848
Autor:
Christian G. Hartinger, Maria S. Legina, Samuel M. Meier-Menches, Cynthia Licona, Michael A. Jakupec, Sarah Theiner, Muhammad Hanif, Michaela Hejl, Martin Pfaffeneder-Kmen, Bernhard K. Keppler, Christophe Orvain, Maria V. Babak, Christian Gaiddon
Publikováno v:
Inorganic Chemistry
Inorganic Chemistry, American Chemical Society, 2018, 57 (5), pp.2851-2864. ⟨10.1021/acs.inorgchem.7b03210⟩
Inorganic Chemistry, 2018, 57 (5), pp.2851-2864. ⟨10.1021/acs.inorgchem.7b03210⟩
Inorganic Chemistry, American Chemical Society, 2018, 57 (5), pp.2851-2864. ⟨10.1021/acs.inorgchem.7b03210⟩
Inorganic Chemistry, 2018, 57 (5), pp.2851-2864. ⟨10.1021/acs.inorgchem.7b03210⟩
We thank Prof. Markus Galanski for providing Pt precursors.; International audience; Platinum-based anticancer coordination compounds are widely used in the treatment of many tumor types, where they are very effective but also cause severe side effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0dea6d18bea763c68583c9bbb48697a
https://www.hal.inserm.fr/inserm-02364163/file/acs.inorgchem.7b03210.pdf
https://www.hal.inserm.fr/inserm-02364163/file/acs.inorgchem.7b03210.pdf
Autor:
Christophe Orvain, Michel Pfeffer, Adel Hamada, Moussa Ali, Jennifer Weckbach, Houda Habbita, Christian Gaiddon
Publikováno v:
Journal of Organometallic Chemistry
Journal of Organometallic Chemistry, Elsevier, 2017, 845, pp.206-212. ⟨10.1016/j.jorganchem.2017.05.022⟩
Journal of Organometallic Chemistry, 2017, 845, pp.206-212. ⟨10.1016/j.jorganchem.2017.05.022⟩
Journal of Organometallic Chemistry, Elsevier, 2017, 845, pp.206-212. ⟨10.1016/j.jorganchem.2017.05.022⟩
Journal of Organometallic Chemistry, 2017, 845, pp.206-212. ⟨10.1016/j.jorganchem.2017.05.022⟩
International audience; Two novel cycloruthenated compounds, 2 and 3, derived from cycloruthenated 2-phenyl pyridine(Ru(PhPy)) have been synthesized by adding one equivalent of 2,20;60,200-terpyridine (terpy) to [Ru(2-C6H4-20-C5H4N-kC,N)(MeCN)4]PF6 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48050abfb0f582d9cbe6bd6832ddaa0
https://www.hal.inserm.fr/inserm-02365254/file/1-s2.0-S0022328X17303182-main.pdf
https://www.hal.inserm.fr/inserm-02365254/file/1-s2.0-S0022328X17303182-main.pdf