Výsledky vyhledávání - "Christophe LeTourneau"

Phase I trial of copanlisib, a selective PI3K inhibitor, in combination with cetuximab in patients with recurrent and/or metastatic head and neck squamous cell carcinoma

Autor: Grégoire Marret, Nicolas Isambert, Keyvan Rezai, Jocelyn Gal, Esma Saada-Bouzid, Frédéric Rolland, Maggy Chausson, Edith Borcoman, Marie Alt, Jerzy Klijanienko, Damien Vansteene, Joël Guigay, Maud Kamal, Ivan Bièche, Christophe LeTourneau

Publikováno v: Investigational new drugs. 39(6)

BackgroundThe phosphatidylinositol-3 kinase pathway is often altered in head and neck squamous cell carcinoma (HNSCC), and is involved in the resistance to EGFR inhibitors. ObjectiveWe investigated the dose-limiting toxicities (DLTs), maximum tolerat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d8fa6291d4a5d09ce556396f62dfbd
https://pubmed.ncbi.nlm.nih.gov/34322775

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