Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Christophe Le Clainche"'
Autor:
Cesar Valencia-Gallardo, Daniel-Isui Aguilar-Salvador, Hamed Khakzad, Benjamin Cocom-Chan, Charles Bou-Nader, Christophe Velours, Yosra Zarrouk, Christophe Le Clainche, Christian Malosse, Diogo Borges Lima, Nicole Quenech’Du, Bilal Mazhar, Sami Essid, Marc Fontecave, Atef Asnacios, Julia Chamot-Rooke, Lars Malmström, Guy Tran Van Nhieu
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112405- (2023)
Summary: Upon activation, vinculin reinforces cytoskeletal anchorage during cell adhesion. Activating ligands classically disrupt intramolecular interactions between the vinculin head and tail domains that bind to actin filaments. Here, we show that
Externí odkaz:
https://doaj.org/article/c7264a6cb8d84810a58eacb247fd705e
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Force-dependent formation of the talin-vinculin complex reinforces actin anchoring to focal adhesions, but how different talin-binding proteins respond to force is unclear. Here authors use an in vitro microscopy assay and show that the actomyosin fo
Externí odkaz:
https://doaj.org/article/e6f4002112094dafbff45c5811349b88
Autor:
Mariem Souissi, Julien Pernier, Olivier Rossier, Gregory Giannone, Christophe Le Clainche, Emmanuèle Helfer, Kheya Sengupta
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6335 (2021)
Giant unilamellar vesicles (GUV) are powerful tools to explore physics and biochemistry of the cell membrane in controlled conditions. For example, GUVs were extensively used to probe cell adhesion, but often using non-physiological linkers, due to t
Externí odkaz:
https://doaj.org/article/7e47070ebb38445b87272dbd2f5d4c76
Autor:
Jan Mueller, Julia Pfanzelter, Christoph Winkler, Akihiro Narita, Christophe Le Clainche, Maria Nemethova, Marie-France Carlier, Yuichiro Maeda, Matthew D Welch, Taro Ohkawa, Christian Schmeiser, Guenter P Resch, J Victor Small
Publikováno v:
PLoS Biology, Vol 12, Iss 1, p e1001765 (2014)
Several pathogens induce propulsive actin comet tails in cells they invade to disseminate their infection. They achieve this by recruiting factors for actin nucleation, the Arp2/3 complex, and polymerization regulators from the host cytoplasm. Owing
Externí odkaz:
https://doaj.org/article/a9a2c84bb8f9439888998f9a715b2226
Publikováno v:
International Journal of Cell Biology, Vol 2012 (2012)
Cell-matrix adhesion plays a major role during cell migration. Proteins from adhesion structures connect the extracellular matrix to the actin cytoskeleton, allowing the growing actin network to push the plasma membrane and the contractile cables (st
Externí odkaz:
https://doaj.org/article/a850f7b93a98413aa1dab4a290cea769
Autor:
Maud Hertzog, Francesca Milanesi, Larnele Hazelwood, Andrea Disanza, HongJun Liu, Emilie Perlade, Maria Grazia Malabarba, Sebastiano Pasqualato, Alessio Maiolica, Stefano Confalonieri, Christophe Le Clainche, Nina Offenhauser, Jennifer Block, Klemens Rottner, Pier Paolo Di Fiore, Marie-France Carlier, Niels Volkmann, Dorit Hanein, Giorgio Scita
Publikováno v:
PLoS Biology, Vol 8, Iss 6, p e1000387 (2010)
Actin capping and cross-linking proteins regulate the dynamics and architectures of different cellular protrusions. Eps8 is the founding member of a unique family of capping proteins capable of side-binding and bundling actin filaments. However, the
Externí odkaz:
https://doaj.org/article/9bb2acf482a74833be574542c89fb8d3
Autor:
Rayan Said, Hong Wang, Julien Pernier, Hemalatha Narassimprakash, Stéphane Roméro, Alexis M. Gautreau, René-Marc Mège, Christophe Le Clainche
The cohesion of tissues requires that cells establish cell-cell junctions. Cells contact each other by forming Arp2/3-dependent lamellipodia before they initiate the formation of cadherin-based adherens junctions (AJs). Maturing AJs then assemble act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ea8b32f93ba2757cdf4c1d442fd7785
https://doi.org/10.1101/2022.12.04.518837
https://doi.org/10.1101/2022.12.04.518837
Autor:
Hong Wang, Clémence Vigouroux, Rayan Said, Véronique Henriot, Julien Pernier, Christophe Le Clainche
Focal adhesions (FAs) strengthen their link with the actin cytoskeleton to resist force. Talin-vinculin association could reinforce actin anchoring to FAs by controlling actin polymerization. However, the actin polymerization activity of the talin-vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8432c3268c11fd04b950180a672ead35
https://doi.org/10.1101/2022.12.01.518757
https://doi.org/10.1101/2022.12.01.518757
Autor:
Cesar Valencia-Gallardo, Daniel-Isui Aguilar-Salvador, Hamed Khakzad, Benjamin Cocom-Chan, Charles Bou-Nader, Christophe Velours, Yosra Zarrouk, Christophe Le Clainche, Christian Malosse, Diogo Borges Lima, Nicole Quenech’Du, Bilal Mazhar, Sami Essid, Marc Fontecave, Atef Asnacios, Julia Chamot-Rooke, Lars Malmström, Guy Tran Van Nhieu
Upon activation, vinculin reinforces cytoskeletal anchorage during cell adhesion. Activating ligands classically disrupt intramolecular interactions between the vinculin head and tail domain that binds to actin filaments. Here, we show thatShigellaIp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f49da36b25d4ce270d6d7a3c42dc5fc
https://doi.org/10.1101/2022.11.07.515412
https://doi.org/10.1101/2022.11.07.515412
Autor:
Julien Pernier, Marcelina Cardoso Dos Santos, Mariem Souissi, Adrien Joly, Hemalatha Narassimprakash, Olivier Rossier, Grégory Giannone, Emmanuèle Helfer, Kheya Sengupta, Christophe Le Clainche
Focal adhesions are important mechanosensitive structures, composed of transmembrane integrins, linking the extracellular matrix to the actomyosin cytoskeleton, via cytoplasmic proteins. Cellular adhesion to the extracellular matrix depends on the ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b4c0b0d0aa2ff65ab5b3a5d5d7ad0e
https://doi.org/10.1101/2022.10.07.511266
https://doi.org/10.1101/2022.10.07.511266