Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Christophe Lanneau"'
Publikováno v:
Target Discovery and Validation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b71586be378f939abb81977ae75eba52
https://doi.org/10.1002/9783527818242.ch9
https://doi.org/10.1002/9783527818242.ch9
Autor:
Céline Nicolazzi, Christophe Lanneau, Cécile Orsini, Sophie Boisrobert-Blais, Georges Kalouche, Eric Parmantier, Clara Soulard
Publikováno v:
Cancer Research. 80:3269-3269
Purpose: The role of Cbl-b as an essential modulator of T cell activation has been widely documented, particularly in mouse studies. To substantiate the effects of Cbl-b ablation in human T cells, gene editing conditions were optimized, and gene KO e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9425c69f9b5006d6e8a2944234f4b64
https://doi.org/10.1158/1538-7445.am2020-3269
https://doi.org/10.1158/1538-7445.am2020-3269
Autor:
Christophe Marcireau, Karine Berthelot, Alice Williart, Hamida Fournet, Delphine Debono, Gilbert Thill, Helene Erasimus, Dorine Chassin, Christophe Lanneau, Veeanagouda Yaligara, Cecile Orsini, Michel Didier, Vincent Mikol, Monsif Bouaboula, Laurent Debussche
Publikováno v:
Cancer Research. 79:1272-1272
Metastatic breast cancer results in substantial morbidity and mortality for women afflicted with this disease. Approximately 80% of breast cancers express the estrogen receptor. The cancer cell survival and proliferation is driven by the activation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32aee58da4359ab28845d0dfb8d62b50
https://doi.org/10.1158/1538-7445.am2019-1272
https://doi.org/10.1158/1538-7445.am2019-1272
Autor:
Thomas Licher, Daniel Bertrand, Jean-Marie Chambard, Isabel A. Lefevre, Bruno Biton, Michel Partiseti, Christophe Lanneau
Publikováno v:
Current Protocols in Pharmacology
Over the last six decades, voltage-gated sodium (Nav ) channels have attracted a great deal of scientific and pharmaceutical interest, driving fundamental advances in both biology and technology. The structure and physiological function of these chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915596759b76970215116367c9696128
https://doi.org/10.1002/cpph.14
https://doi.org/10.1002/cpph.14
Autor:
Bruno Biton, Guy Griebel, Caroline Cohen, Pascal George, Philippe Pichat, Mireille Sevrin, Genevieve Estenne-Bouhtou, Nancy Rogacki, C. Desvignes, Bernard Scatton, Patrick Avenet, Xavier Vigé, Jeanne Stemmelin, Olivier Bergis, Annick Coste, Denis Boulay, Christophe Lanneau, Jean Paul Terranova, Régis Steinberg, R. Alonso, Gihad Dargazanli, F. Oury-Donat
Publikováno v:
Pharmacology Biochemistry and Behavior. 91:47-58
On native human, rat and mouse glycine transporter-1(GlyT1), SSR130800 behaves as a selective inhibitor with IC50 values of 1.9, 5.3 and 6.8 nM, respectively. It reversibly blocked glycine uptake in mouse brain cortical homogenates, increased extrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6687966391f5ff03ce02d4870bfc9701
https://doi.org/10.1016/j.pbb.2008.06.009
https://doi.org/10.1016/j.pbb.2008.06.009
Autor:
Marc Williams Debono, Alistair Lochead, Dominique Françon, Annick Coste, Pascal George, Francoise Chesney, André Oblin, Raphaël Santamaria, Corinne Voltz, Patrick Granger, Danielle Godet, Olivier Bergis, Liliane Rouquier, Alain Nedelec, Georg Andrees Bohme, Bernard Scatton, Samir Jegham, Frederic Galli, Bruno Biton, Guy Griebel, Christiane Gueudet, Vincent Santucci, F. Oury-Donat, David I. Graham, Jacques Léonardon, François Besnard, Régis Steinberg, Frédéric Sgard, Josiane Souilhac, Olivier Curet, Xavier Vigé, Christophe Lanneau, Patrick Avenet
Publikováno v:
Neuropsychopharmacology. 32:1-16
In this paper, we report on the pharmacological and functional profile of SSR180711 (1,4-Diazabicyclo[3.2.2]nonane-4-carboxylic acid, 4-bromophenyl ester), a new selective alpha7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. SSR180711 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259e28ed2f1b66d2920ae44ef537db33
https://doi.org/10.1038/sj.npp.1301189
https://doi.org/10.1038/sj.npp.1301189
Autor:
R. Alonso, Patrick Avenet, Pascal George, Genevieve Estenne-Bouhtou, Martine Poncelet, Jeanne Stemmelin, Annick Coste, Jean Paul Terranova, Bruno Biton, Michel Heaulme, Guy Griebel, Régis Steinberg, Benoit Marabout, C. Desvignes, Christophe Lanneau, Mireille Sevrin, Pierre Roger, Denis Boulay, Xavier Vigé, Dominique Françon, Gihad Dargazanli, Vincent Santucci, Ghislaine Perrault, Philippe Soubrie, Annie Cudennec, Michel Decobert, Ronan Depoortère, F. Oury-Donat, Carolle Voltz, Bernard Scatton
Publikováno v:
Neuropsychopharmacology. 30:1963-1985
Noncompetitive N-methyl-D-aspartate (NMDA) blockers induce schizophrenic-like symptoms in humans, presumably by impairing glutamatergic transmission. Therefore, a compound potentiating this neurotransmission, by increasing extracellular levels of gly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1894ffc0d544f344ccf28ac44c7e7849
https://doi.org/10.1038/sj.npp.1300772
https://doi.org/10.1038/sj.npp.1300772
Autor:
Danniel P. Gitterman, Jenny C. Roberts, John B. Davis, Alison M. Ray, Ceri D. Benham, Mark H Harries, Christopher H. Davies, Catherine H. Gill, Christophe Lanneau
Publikováno v:
The Journal of Neuroscience. 23:10146-10153
Cell death mechanisms frequently involve the influx of extracellular calcium through voltage- and ligand-gated ion channels, e.g., the NMDA receptor (Greene, 1999). The vanilloid receptor (VR1) is present in regions of the brain (Mezey et al., 2000)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ab18d935185384f9c9e686d6788908
https://doi.org/10.1523/jneurosci.23-31-10146.2003
https://doi.org/10.1523/jneurosci.23-31-10146.2003
Autor:
Zsolt Csaba, Christophe Lanneau, Jacques Epelbaum, Lone Helboe, Robert Gardette, Daniel Hoyer, Philippe Zizzari, Gloria Shaffer Tannenbaum, Elisabeth Pellegrini, Pascal Dournaud, Marie Thérèse Bluet-Pajot
Publikováno v:
Endocrinology. 141:967-979
Five somatostatin (SRIH) receptors (sst1–5) have been cloned. Recent anatomical evidence suggests that sst1 and sst2 may be involved in the central regulation of GH secretion. Given the lack of specific receptor antagonists, we used selective antis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92869115660003ce59125ecc2810641b
https://doi.org/10.1210/endo.141.3.7349
https://doi.org/10.1210/endo.141.3.7349
Publikováno v:
Neuroscience. 88:359-364
Cortistatin is a 14-residue putative neuropeptide with strong structural similarity to somatostatin. Even if it shares several biological properties with somatostatin, the effects of cortistatin on cortical electrical activity and sleep are opposite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f0421f979f21d1bbe8f1ef70a22f42e
https://doi.org/10.1016/s0306-4522(98)00413-8
https://doi.org/10.1016/s0306-4522(98)00413-8