Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christophe J Langouët-Astrié"'
Autor:
Miaomiao Li, Chih Yean Ong, Christophe J Langouët-Astrié, Lisi Tan, Ashwni Verma, Yimu Yang, Xiaoxiao Zhang, Dhaval K Shah, Eric P Schmidt, Ding Xu
Publikováno v:
eLife, Vol 11 (2022)
RAGE, a druggable inflammatory receptor, is known to function as an oligomer but the exact oligomerization mechanism remains poorly understood. Previously we have shown that heparan sulfate (HS) plays an active role in RAGE oligomerization. To unders
Externí odkaz:
https://doaj.org/article/fd4241c108454ee0ac24b569c2771b24
Autor:
John J Gildea, Peng Xu, Brandon A Kemp, Julia M Carlson, Hanh T Tran, Dora Bigler Wang, Christophe J Langouët-Astrié, Helen E McGrath, Robert M Carey, Pedro A Jose, Robin A Felder
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0189464 (2018)
RATIONALE:Salt sensitivity of blood pressure affects >30% of the hypertensive and >15% of the normotensive population. Variants of the electrogenic sodium bicarbonate cotransporter NBCe2 gene, SLC4A5, are associated with increased blood pressure in s
Externí odkaz:
https://doaj.org/article/c049ebdd0ff047d0a962475ddd0f8a77
Autor:
Heidi A. Crosby, Klara Keim, Jakub M. Kwiecinski, Christophe J. Langouët-Astrié, Kaori Oshima, Wells B. LaRivière, Eric P. Schmidt, Alexander R. Horswill
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTStaphylococcus aureus is one of the leading causes of hospital-acquired infections, many of which begin following attachment and accumulation on indwelling medical devices or diseased tissue. These infections are often linked to the establish
Externí odkaz:
https://doaj.org/article/58e55729bb694669b833e2b8a927e904
Autor:
James F. Colbert, Joshua M. Kirsch, Christopher L. Erzen, Christophe J. Langouët-Astrié, Grace E. Thompson, Sarah A. McMurtry, Jennifer M. Kofonow, Charles E. Robertson, Elizabeth J. Kovacs, Ryan C. Sullivan, Joseph A. Hippensteel, Namrata V. Sawant, Nicole J. De Nisco, Bruce D. McCollister, Robert S. Schwartz, Alexander R. Horswill, Daniel N. Frank, Breck A. Duerkop, Eric P. Schmidt
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT Prior research has focused on host factors as mediators of exaggerated sepsis-associated morbidity and mortality in older adults. This focus on the host, however, has failed to identify therapies that improve sepsis outcomes in the elderly.
Externí odkaz:
https://doaj.org/article/3534f0ab7eb1418a8befb8cb4e008912
Autor:
Alicia N. Rizzo, Sarah M. Haeger, Kaori Oshima, Yimu Yang, Alison M. Wallbank, Ying Jin, Marie Lettau, Lynda A. McCaig, Nancy E. Wickersham, J. Brennan McNeil, Igor Zakharevich, Sarah A. McMurtry, Christophe J. Langouët-Astrié, Katrina W. Kopf, Dennis R. Voelker, Kirk C. Hansen, Ciara M. Shaver, V. Eric Kerchberger, Ryan A. Peterson, Wolfgang M. Kuebler, Matthias Ochs, Ruud A.W. Veldhuizen, Bradford J. Smith, Lorraine B. Ware, Julie A. Bastarache, Eric P. Schmidt
Publikováno v:
JCI Insight, Vol 7, Iss 2 (2022)
Acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure yet has few pharmacologic therapies, reflecting the mechanistic heterogeneity of lung injury. We hypothesized that damage to the alveolar epithelial glycocalyx, a lay
Externí odkaz:
https://doaj.org/article/31aa2a1550884c5a8f8b113a7914671a
Autor:
Heidi A. Crosby, Klara Keim, Jakub M. Kwiecinski, Christophe J. Langouët-Astrié, Kaori Oshima, Wells B. LaRivière, Eric P. Schmidt, Alexander R. Horswill
Staphylococcus aureusis one of the leading causes of hospital acquired infections, many of which begin following attachment and accumulation on indwelling medical devices or diseased tissue. These infections are often linked to establishment of biofi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf671d539ab2857743a24e6db2665d0a
https://doi.org/10.1101/2022.12.13.520364
https://doi.org/10.1101/2022.12.13.520364
Autor:
Rebecca A, Keogh, Amanda L, Haeberle, Christophe J, Langouët-Astrié, Jeffrey S, Kavanaugh, Eric P, Schmidt, Garrett D, Moore, Alexander R, Horswill, Kelly S, Doran
Publikováno v:
Science advances. 8(45)
Diabetic wounds have poor healing outcomes due to the presence of numerous pathogens and a dysregulated immune response. Group B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e49ede3541003570fa4cbdfa78b74c8f
https://pubmed.ncbi.nlm.nih.gov/36367946
https://pubmed.ncbi.nlm.nih.gov/36367946
Autor:
Rebecca A. Keogh, Amanda L. Haeberle, Christophe J. Langouët-Astrié, Jeffrey S. Kavanaugh, Eric P. Schmidt, Garrett D. Moore, Alexander R. Horswill, Kelly S. Doran
Publikováno v:
Science Advances. 8
Diabetic wounds have poor healing outcomes due to the presence of numerous pathogens and a dysregulated immune response. Group BStreptococcus(GBS) is commonly isolated from diabetic wound infections, but the mechanisms of GBS virulence during these i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5eb4c63bed32640c02a4c8c7ec73ab5
https://doi.org/10.1126/sciadv.add3221
https://doi.org/10.1126/sciadv.add3221
Group B Streptococcus Adaptation Promotes Survival in a Hyperinflammatory Diabetic Wound Environment
Autor:
Rebecca A. Keogh, Amanda L. Haeberle, Christophe J. Langouët-Astrié, Jeffrey S. Kavanaugh, Eric P. Schmidt, Garrett D. Moore, Alexander R. Horswill, Kelly S. Doran
Diabetic wounds have poor healing outcomes due to the presence of numerous pathogens and a dysregulated immune response. Group BStreptococcus(GBS) is commonly isolated from diabetic wound infections, but the mechanisms of GBS virulence during these i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fb3924847c8822eb39be983146a2fc7
https://doi.org/10.1101/2022.06.27.497804
https://doi.org/10.1101/2022.06.27.497804
Autor:
Miaomiao Li, Chih Yean Ong, Christophe J Langouët-Astrié, Lisi Tan, Ashwni Verma, Yimu Yang, Xiaoxiao Zhang, Dhaval K Shah, Eric P Schmidt, Ding Xu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1e54c6c086845a2f6f70e078e90b07d
https://doi.org/10.7554/elife.71403.sa2
https://doi.org/10.7554/elife.71403.sa2