Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Christophe Heiss"'
Autor:
Don Antoine Lanfranchi, Françoise Colobert, Frédéric R. Leroux, Laurence Bonnafoux, Christophe Heiss
Publikováno v:
Advanced Synthesis & Catalysis. 349:2705-2713
Upon treatment of various aryllithium intermediates with 1,2-dibromobenzene or 1-bromo-2-iodobenzene, dissymmetrical ortho,ortho′-di-, tri- and even tetrasubstituted bromo- or iodobiaryls become readily available. The crucial steps in all these rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::266a2f139795d1e67a299efe48490912
https://doi.org/10.1002/adsc.200700211
https://doi.org/10.1002/adsc.200700211
Publikováno v:
European Journal of Organic Chemistry. 2006:4398-4404
Nine 1,3-dichlorobenzene congeners were selected as model compds. to assess the relative rates of proton abstraction from 4- and 5-positions ("ortho" vs. "meta" metalation). Using lithium 2,2,6,6-tetramethylpiperidide as the basic reagent, the chlori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0024fc2f13f22174ea4e59477f950b81
https://doi.org/10.1002/ejoc.200600350
https://doi.org/10.1002/ejoc.200600350
Publikováno v:
European Journal of Organic Chemistry. 2005:5242-5247
(2,6-Difluorophenyl)trimethylsilane, -triethylsilane and -triisopropylsilane undergo sec-butyllithium-mediated metalation at the 3- and 4-position (ortho and meta relative to the halogen) in ratios of 99.6:0.4, 98:2 and 95:5, resp. The steric pressur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef669a60a368ce2301750cc952fe230e
https://doi.org/10.1002/ejoc.200500552
https://doi.org/10.1002/ejoc.200500552
Publikováno v:
European Journal of Organic Chemistry. 2005:5236-5241
(2,6-Dichlorophenyl)trimethyl- and -triethylsilane exhibit untypical reactivity patterns toward strong bases. When treated at -100 DegC with lithium 2,2,6,6-tetramethylpiperidide, they give rise to two, with sec- or tert-butyllithium even three, diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa18a65c8f792e48fc32cd5232451d41
https://doi.org/10.1002/ejoc.200500553
https://doi.org/10.1002/ejoc.200500553
Publikováno v:
Synthesis. 2005:617-621
Deprotonation-triggered heavy halogen migrations should become a favorite tool in arene synthesis if their occurrence and outcome could be made predictable. Particularly attractive, though extremely rare, are stop-and-go situations where a first inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed8a5d85db3727bc5a8637b75e73cca
https://doi.org/10.1055/s-2005-861787
https://doi.org/10.1055/s-2005-861787
Autor:
Manfred Schlosser, Christophe Heiss
Publikováno v:
European Journal of Organic Chemistry. 2003:447-451
In a case study, 1,2,3-trifluorobenzene was functionalized at each of the two vacant positions [producing the benzoic acids HO2CC6H2F3-2,3,4 F(I) and HO2CC6H2F3-3,4,5 (I)] and, in addn., bromine was introduced into all available positions of I and II
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fb0131be9ccd916ad89c42b8f0d1e6
https://doi.org/10.1002/ejoc.200390078
https://doi.org/10.1002/ejoc.200390078
Publikováno v:
European Journal of Organic Chemistry. 2006:735-737
Triethyl[(2-trifluoromethyl)phenyl]silane reacts with the superbasic LIC-KOR mixt. of butyllithium and potassium tert-butoxide exclusively at the 4-position ("meta-metalation") and not at all at the 3-position ("ortho-metalation"). Two further substr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efac57c9159ba44c58fcb18018e21878
https://doi.org/10.1002/ejoc.200500729
https://doi.org/10.1002/ejoc.200500729
Publikováno v:
Organic Letters. 6:4591-4593
(2,6-Dichlorophenyl)- and (2,6-dibromophenyl)trialkylsilanes undergo hydrogen/metal interconversion preferentially at the 4- rather than 3-position. However, the organometallic species generated by such a "meta metalation" are thermodynamically less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12ae12af2ce7080878a359a6c6aacdf
https://doi.org/10.1021/ol0480022
https://doi.org/10.1021/ol0480022
Autor:
Christophe Heiss, Frédéric R. Leroux, Laurence Bonnafoux, Don Antoine Lanfranchi, Françoise Colobert
Publikováno v:
ChemInform. 39
Upon treatment of various aryllithium intermediates with 1,2-dibromobenzene or 1-bromo-2-iodobenzene, dissymmetrical ortho,ortho′-di-, tri- and even tetrasubstituted bromo- or iodobiaryls become readily available. The crucial steps in all these rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0819531023434dd1c0b53a373793227
https://doi.org/10.1002/chin.200816099
https://doi.org/10.1002/chin.200816099
Publikováno v:
European Journal of Organic Chemistry
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2006, 2007 (4), pp.669-675. ⟨10.1002/ejoc.200600589⟩
European Journal of Organic Chemistry, 2006, 2007 (4), pp.669-675. ⟨10.1002/ejoc.200600589⟩
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2006, 2007 (4), pp.669-675. ⟨10.1002/ejoc.200600589⟩
European Journal of Organic Chemistry, 2006, 2007 (4), pp.669-675. ⟨10.1002/ejoc.200600589⟩
International audience; (2-Fluorophenyl)trimethylsilane (2-F) and (2-chlorophenyl)trimethylsilane (2-Cl) react with sec-butyllithium or lithium 2,2,6,6-tetramethylpiperidide under permutational hydrogen/metal interconversion (metalation) more slowly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5da1ee58bf54b50e2721389406afb5
https://hal.archives-ouvertes.fr/hal-01002829
https://hal.archives-ouvertes.fr/hal-01002829
