Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christophe Georger"'
Autor:
Nathalie Bourg, Ai Vu Hong, William Lostal, Abbass Jaber, Nicolas Guerchet, Guillaume Tanniou, Fanny Bordier, Emilie Bertil-Froidevaux, Christophe Georger, Nathalie Daniele, Isabelle Richard, David Israeli
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2016 (2022)
Duchenne muscular dystrophy (DMD) is the most common and cureless muscle pediatric genetic disease, which is caused by the lack or the drastically reduced expression of dystrophin. Experimental therapeutic approaches for DMD have been mainly focused
Externí odkaz:
https://doaj.org/article/b33d5a168eaa421083eccfe1b5d5b3d0
Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy
Autor:
Caroline Le Guiner, Laurent Servais, Marie Montus, Thibaut Larcher, Bodvaël Fraysse, Sophie Moullec, Marine Allais, Virginie François, Maeva Dutilleul, Alberto Malerba, Taeyoung Koo, Jean-Laurent Thibaut, Béatrice Matot, Marie Devaux, Johanne Le Duff, Jack-Yves Deschamps, Inès Barthelemy, Stéphane Blot, Isabelle Testault, Karim Wahbi, Stéphane Ederhy, Samia Martin, Philippe Veron, Christophe Georger, Takis Athanasopoulos, Carole Masurier, Federico Mingozzi, Pierre Carlier, Bernard Gjata, Jean-Yves Hogrel, Oumeya Adjali, Fulvio Mavilio, Thomas Voit, Philippe Moullier, George Dickson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Duchenne muscular dystrophy is a progressive degenerative disease of muscles caused by mutations in the dystrophin gene. Here the authors use AAV vectors to deliver microdystrophin to dogs with muscular dystrophy, and show restoration of dystrophin e
Externí odkaz:
https://doaj.org/article/d425f7f6bf364aa99c6850ae61ecdd6b
Autor:
Jean-Baptiste Dupont, Benoit Tournaire, Christophe Georger, Béatrice Marolleau, Laurence Jeanson-Leh, Mireille Ledevin, Pierre Lindenbaum, Emilie Lecomte, Benjamin Cogné, Laurence Dubreil, Thibaut Larcher, Bernard Gjata, Laetitia Van Wittenberghe, Caroline Le Guiner, Magalie Penaud-Budloo, Richard O Snyder, Philippe Moullier, Adrien Léger
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
Preclinical gene therapy strategies using recombinant adeno-associated virus (AAV) vectors in animal models of Duchenne muscular dystrophy have shown dramatic phenotype improvements, but long-lasting efficacy remains questionable. It is believed that
Externí odkaz:
https://doaj.org/article/846a902b7ddb4553bb393762ce9f0d6f
Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy
Autor:
Virginie François, Oumeya Adjali, Jean-Yves Hogrel, George Dickson, Thibaut Larcher, Maeva Dutilleul, Taeyoung Koo, Marie Montus, Stéphane Ederhy, Stéphane Blot, M. Allais, Carole Masurier, Alberto Malerba, Marie Devaux, B. Matot, Karim Wahbi, Sophie Moullec, Bernard Gjata, Bodvael Fraysse, Laurent Servais, Fulvio Mavilio, Inès Barthélémy, Pierre G. Carlier, Takis Athanasopoulos, Isabelle Testault, Samia Martin, Jack-Yves Deschamps, Philippe Moullier, Federico Mingozzi, Philippe Veron, Christophe Georger, Johanne Le Duff, Caroline Le Guiner, Thomas Voit, Jean-Laurent Thibaut
Publikováno v:
Nature Communications
Nature Communications, 2017, 8 (1), pp.16105. ⟨10.1038/ncomms16105⟩
Nature communications (8), 16105. (2017)
Nature Communications, Nature Publishing Group, 2017, 8 (1), pp.16105. ⟨10.1038/ncomms16105⟩
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications, 2017, 8 (1), pp.16105. ⟨10.1038/ncomms16105⟩
Nature communications (8), 16105. (2017)
Nature Communications, Nature Publishing Group, 2017, 8 (1), pp.16105. ⟨10.1038/ncomms16105⟩
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Duchenne muscular dystrophy (DMD) is an incurable X-linked muscle-wasting disease caused by mutations in the dystrophin gene. Gene therapy using highly functional microdystrophin genes and recombinant adeno-associated virus (rAAV) vectors is an attra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c348d77df95e4b68a2b7f4ada280b2b
https://univ-evry.hal.science/hal-02179396
https://univ-evry.hal.science/hal-02179396
Autor:
Adrien Leger, Bernard Gjata, Benjamin Cogné, Laetitia van Wittenberghe, Benoît Tournaire, Jean-Baptiste Dupont, Alban Vignaud, Christophe Georger, Romain Durand, Béatrice Marolleau, Richard O. Snyder, Emilie Bertil, Emilie Lecomte, Philippe Moullier
Publikováno v:
Les Cahiers de Myologie. :99-101
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9574439f8c92f990f0c38edea2d7f9c2
https://doi.org/10.1051/myolog/201613021
https://doi.org/10.1051/myolog/201613021
Autor:
Laetitia van Wittenberghe, Antoine Kichler, Christophe Georger, Simon Guiraud, Daniel Scherman
Publikováno v:
Neuromuscular Disorders
Neuromuscular Disorders, Elsevier, 2012, 22 (12), pp.1057-1068. ⟨10.1016/j.nmd.2012.07.002⟩
Neuromuscular Disorders, 2012, 22 (12), pp.1057-1068. ⟨10.1016/j.nmd.2012.07.002⟩
Neuromuscular Disorders, Elsevier, 2012, 22 (12), pp.1057-1068. ⟨10.1016/j.nmd.2012.07.002⟩
Neuromuscular Disorders, 2012, 22 (12), pp.1057-1068. ⟨10.1016/j.nmd.2012.07.002⟩
International audience; Decorin is a member of the small leucine-rich proteoglycan family and it is a component of the extracellular matrix. Decorin was previously shown to bind different molecules, including myostatin, in a zinc-dependent manner. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8596fbfab740df28c45e0065245202b
https://hal-univ-evry.archives-ouvertes.fr/hal-02179402
https://hal-univ-evry.archives-ouvertes.fr/hal-02179402
Autor:
Bernard Gjata, Benoît Tournaire, Alban Vignaud, Christophe Georger, Philippe Moullier, Romain Durand, Adrien Leger, Jean-Baptiste Dupont, Emilie Lecomte, Benjamin Cogné, Richard O. Snyder, Emilie Bertil, Béatrice Marolleau, Laetitia vanWittenberghe
Publikováno v:
Molecular Therapy. 24:S155
Recombinant adeno-associated virus (rAAV)-based vectors are promising tools for the treatment of Duchenne muscular dystrophy (DMD) by gene therapy. Following rAAV injection in murine and canine models of DMD, several groups have reported significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71d504945486ef9ded42326ebe2327c3
https://doi.org/10.1016/s1525-0016(16)33199-9
https://doi.org/10.1016/s1525-0016(16)33199-9
Publikováno v:
Gene Therapy. Nov2010, Vol. 17 Issue 11, p1400-1410. 11p. 1 Color Photograph, 1 Diagram, 4 Graphs.
Autor:
Gerard, X.1, Vignaud, L.1, Charles, S.1, Pinset, C.2, Scherman, D.1, Kichler, A.1, Israeli, D.1 israeli@genethon.fr
Publikováno v:
Gene Therapy. Jun2009, Vol. 16 Issue 6, p815-819. 5p. 1 Diagram, 1 Chart, 4 Graphs.
Autor:
Bourg, Nathalie1,2 (AUTHOR) bourg@genethon.fr, Vu Hong, Ai1,2 (AUTHOR) avuhong@genethon.fr, Lostal, William1,2 (AUTHOR) wlostal@genosafe.com, Jaber, Abbass1,2 (AUTHOR) ajaber@genethon.fr, Guerchet, Nicolas1,2 (AUTHOR) guerchet@genethon.fr, Tanniou, Guillaume1,2 (AUTHOR) gtanniou@genethon.fr, Bordier, Fanny1,2 (AUTHOR) fbordier@genethon.fr, Bertil-Froidevaux, Emilie1,2 (AUTHOR) ebertil@genethon.fr, Georger, Christophe1,2 (AUTHOR) georger@genethon.fr, Daniele, Nathalie1,2 (AUTHOR) daniele@genethon.fr, Richard, Isabelle1,2 (AUTHOR) richard@genethon.fr, Israeli, David1,2 (AUTHOR) israeli@genethon.fr
Publikováno v:
International Journal of Molecular Sciences. Feb2022, Vol. 23 Issue 4, p2016. 1p.