Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christophe Garcie"'
Autor:
Camille V. Chagneau, Christophe Garcie, Nadège Bossuet-Greif, Sophie Tronnet, Alexander O. Brachmann, Jörn Piel, Jean-Philippe Nougayrède, Patricia Martin, Eric Oswald
Publikováno v:
mSphere, Vol 4, Iss 5 (2019)
ABSTRACT Colibactin is a polyketide/nonribosomal peptide produced by Escherichia coli strains that harbor the pks island. This toxin induces DNA double-strand breaks and DNA interstrand cross-links in infected eukaryotic cells. Colibactin-producing s
Externí odkaz:
https://doaj.org/article/f385369a64724228830f1876acd7b499
Autor:
Patricia Martin, Ingrid Marcq, Giuseppe Magistro, Marie Penary, Christophe Garcie, Delphine Payros, Michèle Boury, Maïwenn Olier, Jean-Philippe Nougayrède, Marc Audebert, Christian Chalut, Sören Schubert, Eric Oswald
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003437 (2013)
In Escherichia coli, the biosynthetic pathways of several small iron-scavenging molecules known as siderophores (enterobactin, salmochelins and yersiniabactin) and of a genotoxin (colibactin) are known to require a 4'-phosphopantetheinyl transferase
Externí odkaz:
https://doaj.org/article/a1884c7b1e144e7b8e02e9a80d518060
Autor:
Alexander O. Brachmann, Eric Oswald, Christophe Garcie, Sophie Tronnet, Patricia Martin, Jörn Piel
Publikováno v:
Pathogens and Disease
Pathogens and Disease, Oxford University Press, 2017, 75 (5), ⟨10.1093/femspd/ftx066⟩
Pathogens and Disease, 75 (5)
Pathogens and Disease 5 (75), . (2017)
Pathogens and Disease, Oxford University Press, 2017, 75 (5), ⟨10.1093/femspd/ftx066⟩
Pathogens and Disease, 75 (5)
Pathogens and Disease 5 (75), . (2017)
Pathogens and Disease, 75 (5)
ISSN:2049-632X
ISSN:2049-632X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bea10b38bde1e676d04a1410efca3d6
https://hal.archives-ouvertes.fr/hal-01603279
https://hal.archives-ouvertes.fr/hal-01603279
Publikováno v:
IUBMB Life
IUBMB Life, Wiley, 2017, 69 (6), pp.435-441. ⟨10.1002/iub.1612⟩
IUBMB Life, 2017, 69 (6), pp.435-441. ⟨10.1002/iub.1612⟩
IUBMB Life, Wiley, 2017, 69 (6), pp.435-441. ⟨10.1002/iub.1612⟩
IUBMB Life, 2017, 69 (6), pp.435-441. ⟨10.1002/iub.1612⟩
Highly pathogenic Escherichia coli strains that belong to the phylogenetic group B2 have developed a greater ability to acquire iron (heme receptor and numerous siderophores), to produce the genotoxin colibactin and to synthesize antimicrobial sidero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5febc7f9ab1953b69673bcb383b7b219
https://hal.inrae.fr/hal-02619476
https://hal.inrae.fr/hal-02619476
Autor:
Alexander O. Brachmann, Jörn Piel, Alex J. McCarthy, Sébastien Houle, Eric Oswald, Christophe Garcie, Jean-Philippe Nougayrède, Pierre Genevaux, Peter W. Taylor, Amélie Garénaux, Patricia Martin, Sophie Tronnet, Marie Penary, Charles M. Dozois
Publikováno v:
Journal of Infectious Diseases
Journal of Infectious Diseases, 2016, 214 (6), pp.916-924. ⟨10.1093/infdis/jiw294⟩
Journal of Infectious Diseases, Oxford University Press (OUP), 2016, 214 (6), pp.916-924. ⟨10.1093/infdis/jiw294⟩
Journal of Infectious Diseases, 2016, 214 (6), pp.916-924. ⟨10.1093/infdis/jiw294⟩
Journal of Infectious Diseases, Oxford University Press (OUP), 2016, 214 (6), pp.916-924. ⟨10.1093/infdis/jiw294⟩
International audience; The genotoxin colibactin synthesized by Escherichia coli is a secondary metabolite belonging to the chemical family of hybrid polyketide/non-ribosomal peptide compounds. It is produced by a complex biosynthetic assembly line e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd08e4dfa7f7c50230560426800aea0
https://hal-riip.archives-ouvertes.fr/pasteur-01351061
https://hal-riip.archives-ouvertes.fr/pasteur-01351061
Autor:
Sophie Tronnet, Christophe Garcie, Patricia Martin, Nadine Rehm, Eric Oswald, Ulrich Dobrindt
Publikováno v:
Infection and Immunity
Infection and Immunity, 2016, 84 (12), pp.3358-3368. ⟨10.1128/IAI.00659-16⟩
Infection and Immunity 12 (84), 3358-3368. (2016)
Infection and Immunity, American Society for Microbiology, 2016, 84 (12), pp.3358-3368. ⟨10.1128/IAI.00659-16⟩
Infection and Immunity, 2016, 84 (12), pp.3358-3368. ⟨10.1128/IAI.00659-16⟩
Infection and Immunity 12 (84), 3358-3368. (2016)
Infection and Immunity, American Society for Microbiology, 2016, 84 (12), pp.3358-3368. ⟨10.1128/IAI.00659-16⟩
The genotoxin colibactin is a secondary metabolite produced by a variety of pathogenic enterobacteria. Its biosynthesis requires the enzymatic activity of the phosphopantetheinyl transferase (PPTase) ClbA. We previously showed that ClbA can also cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5ffe6e8dc6fa203e146242db213810
https://hal.science/hal-01605475/document
https://hal.science/hal-01605475/document
Colibactin biosynthesis and biological activity depend on the rare aminomalonyl polyketide precursor
Autor:
Jörn Piel, Reiko Ueoka, Patricia Martin, Christophe Garcie, Vincen Wu, Alexander O. Brachmann, Eric Oswald
Publikováno v:
Chemical Communications
Chemical Communications, Royal Society of Chemistry, 2015, 51 (66), pp.13138-13141. ⟨10.1039/c5cc02718g⟩
Chemical Communications, Royal Society of Chemistry, 2015, 51 (66), pp.13138-13141. ⟨10.1039/c5cc02718g⟩
International audience; The as-yet unidentified E. coli metabolite colibactin induces DNA damage in eukaryotic cells and promotes tumorigenesis. Its wide distribution in pathogenic and probiotic strains has raised great interest in its structure and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eebfc2f3786b7716019d9661601fe34c
https://hal.inrae.fr/hal-02636466
https://hal.inrae.fr/hal-02636466
Autor:
Eric Oswald, Christian Chalut, Marie Penary, Patricia Martin, Maïwenn Olier, Jean-Philippe Nougayrède, Delphine Payros, Michèle Boury, Marc Audebert, Christophe Garcie, Ingrid Marcq, Sören Schubert, Giuseppe Magistro
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2013, 9 (7), pp.e1003437. ⟨10.1371/journal.ppat.1003437⟩
PLoS Pathogens, Vol 9, Iss 7, p e1003437 (2013)
Plos Pathogens 7 (9), . (2013)
PLoS Pathogens, 2013, 9 (7), pp.e1003437. ⟨10.1371/journal.ppat.1003437⟩
PLoS Pathogens, Public Library of Science, 2013, 9 (7), pp.e1003437. ⟨10.1371/journal.ppat.1003437⟩
PLoS Pathogens, Vol 9, Iss 7, p e1003437 (2013)
Plos Pathogens 7 (9), . (2013)
PLoS Pathogens, 2013, 9 (7), pp.e1003437. ⟨10.1371/journal.ppat.1003437⟩
In Escherichia coli, the biosynthetic pathways of several small iron-scavenging molecules known as siderophores (enterobactin, salmochelins and yersiniabactin) and of a genotoxin (colibactin) are known to require a 4′-phosphopantetheinyl transferas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba8adbff1f1ebacdb5f4e375de138cb
https://hal.archives-ouvertes.fr/hal-02391854
https://hal.archives-ouvertes.fr/hal-02391854