Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Christophe Galtier"'
Autor:
Christophe Pannecouque, Erik De Clercq, Myriam Witvrouw, Jan Balzarini, Sylvie Mavel, Robert Snoeck, Alain Gueiffier, Christophe Galtier, Graciela Andrei
Publikováno v:
Antiviral Chemistry and Chemotherapy. 14:177-182
The synthesis of novel substituted 3-aralkylth-iomethylimidazo[1,2- b]pyridazines is reported. All of the synthesized compounds are devoid of antiviral activity against the replication of human immunodeficiency virus. However, compounds 6-chloro-8-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd46090475b653714a41bec31e5262bc
https://doi.org/10.1177/095632020301400402
https://doi.org/10.1177/095632020301400402
Publikováno v:
Journal of Heterocyclic Chemistry. 39:737-742
The synthesis of 2-substitutedimidazo[1,2-b]pyridazines and their reactivity towards electrophilic substitutions are reported. The nitration was shown to be very dependent on the nature of the 2 substituent. Nitrosation using sodium nitrite in acetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94451238934649dad782a2691c83d9c0
https://doi.org/10.1002/jhet.5570390419
https://doi.org/10.1002/jhet.5570390419
Autor:
Christophe Galtier, Robert Snoeck, Graciella Andrei, Jan Balzarini, Erik De Clercq, Alain Gueiffier, Sylvie Mavel, Jean‐Louis Renou, Hassan Allouchi
Publikováno v:
Bioorganic & Medicinal Chemistry. 10:941-946
The synthesis of various 2-substituted imidazo[1,2-a]pyridine bearing a thioether side chain in position 3 was reported. The new compounds were characterized by 1H and 13C NMR spectra. A conformational study was obtained by X-ray crystallographic ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd1f094650cf22631a5b92da5bddb279
https://doi.org/10.1016/s0968-0896(01)00347-9
https://doi.org/10.1016/s0968-0896(01)00347-9
Autor:
Patrice Vanelle, Christophe Galtier, Thierry Terme, Joséa Maldonado, Alain Gueiffier, Michel P. Crozet
Publikováno v:
Journal of Heterocyclic Chemistry. 39:173-177
A new heterocyclic reductive alkylating agent, 6-chloro-2-chloromethyl-3-nitroimidazo[1,2-b]pyridazine, was synthesized for the first time. It was shown to react under phase-transfer catalysis conditions with 2-nitropropane anion by an SRN1 mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ecbd8ef9aedaf32510f6b84db6d6e62
https://doi.org/10.1002/jhet.5570390125
https://doi.org/10.1002/jhet.5570390125
Autor:
Cecile Enguehard, Abdelhak Kherbeche, Alain Gueiffier, J. C. Debouzy, Christophe Pannecouque, Olivier Chavignon, Myriam Witvrouw, Erik De Clercq, Christophe Galtier, Aziz Chaouni-Benabdallah, Jan Balzarini, Jean-Claude Teulade, Hassan Allouchi
Publikováno v:
Archiv der Pharmazie. 334:224-228
Ten 2-aryl or heteroaryl-3-nitrosoimidazo[1,2-a]pyridine derivatives were synthesised as potential antiretroviral agents. The new compounds were characterized by elemental analysis, 1H NMR, and by crystallography for (14). The compounds were devoid o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85cc1c461c9486d3233473c445b77f4
https://doi.org/10.1002/1521-4184(200107)334:7<224::aid-ardp224>3.0.co
https://doi.org/10.1002/1521-4184(200107)334:7<224::aid-ardp224>3.0.co
Autor:
Christophe Pannecouque, Myriam Witvrouw, Abdelak Kherbeche, Christophe Galtier, Jean-Claude Teulade, Olivier Chavignon, Jan Balzarini, Alain Gueiffier, Cecile Enguehard, Robert Snoeck, Erik De Clercq, Hassan Allouchi, Aziz Chaouni-Benabdallah, Florence Fauvelle, Graciela Andrei
Publikováno v:
Chemical and Pharmaceutical Bulletin. 49:1631-1635
This work reports the synthesis and the antiviral activities of 3-benzamido, 3-phenylureido and 3-phenylthioureido derivatives in the imidazo[1,2-a]pyridine series. The structure was proven by NMR spectroscopy. The synthesized compounds were evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a33a736945a3b4ec468b8765bc1ab5d
https://doi.org/10.1248/cpb.49.1631
https://doi.org/10.1248/cpb.49.1631
Publikováno v:
Phytochemistry. 51:999-1004
From the latex of Lapsana communis L. subps. communis, five guaianolide glycosides were identified: crepiside E, tectoroside and three new ones: 3-O-beta-D-glucopyranosyl-8-O-beta-acetyl-1 alpha H,5 alpha H,6 beta H,7 alpha H-guai-4(15),10(14),11(13)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a6ac8ac275e6cae2d571ebd083ae4e8
https://doi.org/10.1016/s0031-9422(98)00718-3
https://doi.org/10.1016/s0031-9422(98)00718-3
Autor:
Graciela Andrei, Christophe Galtier, Alain Gueiffier, Erik De Clercq, Jan Balzarini, Sylvie Mavel, Robert Snoeck, Jean Louis Renou
Publikováno v:
ChemInform. 32
The synthesis and antiviral activity of original dibromoimidazo[1,2-a]pyridines bearing a thioether side chain are reported. Molecular modeling was used to identify biophoric structural patterns that are common to 16 compounds. Structure-activity rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa403e437648a86a9ec86d1fe3f38193
https://doi.org/10.1002/chin.200132149
https://doi.org/10.1002/chin.200132149
Autor:
Alain Gueiffier, Patrice Vanelle, Christophe Galtier, Thierry Terme, José Maldonado, Michel P. Crozet
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6aaa12a0256dacc1032ca6810af791c7
https://doi.org/10.1002/chin.200228188
https://doi.org/10.1002/chin.200228188
Autor:
Alain Gueiffier, Jean‐Louis Renou, Christophe Galtier, Jan Balzarini, Sylvie Mavel, Robert Snoeck, Hassan Allouchi, Erik De Clercq, Graciella Andrei
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c2e8de74dd2b3a37850b4f5564767aa
https://doi.org/10.1002/chin.200220121
https://doi.org/10.1002/chin.200220121