Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Christophe E Pierreux"'
Autor:
Jean-Bernard Beaudry, Sabine Cordi, Céline Demarez, Sébastien Lepreux, Christophe E Pierreux, Frédéric P Lemaigre
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0132295 (2015)
Biliary cysts in adult patients affected by polycystic liver disease are lined by cholangiocytes that proliferate, suggesting that initiation of cyst formation depends on proliferation. Here, we challenge this view by analyzing cyst-lining cell proli
Externí odkaz:
https://doaj.org/article/fe5de6316ad443bd9d3d3e83f198082f
Autor:
Shlomit Edri, Vardit Rosenthal, Or Ginsburg, Abigail Newman Frisch, Christophe E. Pierreux, Nadav Sharon, Shulamit Levenberg
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109959- (2024)
Summary: The developing mouse pancreas is surrounded by mesoderm compartments providing signals that induce pancreas formation. Most pancreatic organoid protocols lack this mesoderm niche and only partially capture the pancreatic cell repertoire. Thi
Externí odkaz:
https://doaj.org/article/b686661aaa5b421eb68d0d54411a9507
Autor:
Mauriane Maja, Marie Verfaillie, Patrick Van Der Smissen, Patrick Henriet, Christophe E. Pierreux, Nor Eddine Sounni, Donatienne Tyteca
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background Breast cancer clinical outcome relies on its intrinsic molecular subtype and mortality is almost exclusively due to metastasis, whose mechanism remains unclear. We recently revealed the specific contribution of plasma membrane cho
Externí odkaz:
https://doaj.org/article/148eabf81f0749c89915c407fde3ee39
Autor:
Marine Ghodsi, Anne-Sophie Cloos, Negar Mozaheb, Patrick Van Der Smissen, Patrick Henriet, Christophe E. Pierreux, Nicolas Cellier, Marie-Paule Mingeot-Leclercq, Tomé Najdovski, Donatienne Tyteca
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/ca76d2c2bda642328d2d5c22da4792e2
Autor:
Marine Ghodsi, Anne-Sophie Cloos, Negar Mozaheb, Patrick Van Der Smissen, Patrick Henriet, Christophe E. Pierreux, Nicolas Cellier, Marie-Paule Mingeot-Leclercq, Tomé Najdovski, Donatienne Tyteca
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Transfusion of red blood cell concentrates is the most common medical procedure to treat anaemia. However, their storage is associated with development of storage lesions, including the release of extracellular vesicles. These vesicles affect in vivo
Externí odkaz:
https://doaj.org/article/c8ce20e4cbd84e779c56a16e2b9eb5f9
Autor:
Juliette Vanderroost, Thibaud Parpaite, Noémie Avalosse, Patrick Henriet, Christophe E. Pierreux, Joseph H. Lorent, Philippe Gailly, Donatienne Tyteca
Publikováno v:
Cells, Vol 12, Iss 24, p 2784 (2023)
A specific plasma membrane distribution of the mechanosensitive ion channel Piezo1 is required for cell migration, but the mechanism remains elusive. Here, we addressed this question using WT and Piezo1-silenced C2C12 mouse myoblasts and WT and Piezo
Externí odkaz:
https://doaj.org/article/10372010d4fc40468ca324efa4dbff45
Autor:
Amaury Stommen, Marine Ghodsi, Anne-Sophie Cloos, Louise Conrard, Andra C. Dumitru, Patrick Henriet, Christophe E. Pierreux, David Alsteens, Donatienne Tyteca
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 51 (2023)
Piezo1 is a mechanosensitive ion channel required for various biological processes, but its regulation remains poorly understood. Here, we used erythrocytes to address this question since they display Piezo1 clusters, a strong and dynamic cytoskeleto
Externí odkaz:
https://doaj.org/article/6f6df9e4557547c3bcc459ac8a573a93
Autor:
Manon Moulis, Steve Vincent Maurice Runser, Laura Glorieux, Nicolas Dauguet, Christophe Vanderaa, Laurent Gatto, Donatienne Tyteca, Patrick Henriet, Francesca M. Spagnoli, Dagmar Iber, Christophe E. Pierreux
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Development of the pancreas is driven by an intrinsic program coordinated with signals from other cell types in the epithelial environment. These intercellular communications have been so far challenging to study because of the low concentra
Externí odkaz:
https://doaj.org/article/3635ecf0825b4dbab51e89b71438d34e
Autor:
Arístides López-Márquez, Carlos Carrasco-López, Andrea Martínez-Cano, Pascale Lemoine, Christophe E. Pierreux, Pilar Santisteban
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract While the signaling pathways and transcription factors involved in the differentiation of thyroid follicular cells, both in embryonic and adult life, are increasingly well understood, the underlying mechanisms and potential crosstalk between
Externí odkaz:
https://doaj.org/article/f6dbc66e26cc4015a2e84d20c6ec27d0
Autor:
Eloïse Claude, Guillaume de Lhoneux, Christophe E. Pierreux, Etienne Marbaix, Maëlle de Ville de Goyet, Cécile Boulanger, An Van Damme, Bénédicte Brichard, Anabelle Decottignies
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-16 (2021)
Abstract The vast majority of adult cancer cells achieve cellular immortality by activating a telomere maintenance mechanism (TMM). While this is mostly achieved by the de-silencing of hTERT telomerase gene expression, an alternative homologous recom
Externí odkaz:
https://doaj.org/article/02307fbeea694d559dabdfc3471879e2