Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Christophe Curti"'
Autor:
Nicolas Primas, Caroline Castera-Ducros, Romain Paoli-Lombardo, Christophe Curti, Fanny Mathias, Pascal Rathelot, Pascal Marchand, Patrice Vanelle
Publikováno v:
Drugs and Drug Candidates, Vol 3, Iss 1, Pp 209-243 (2024)
The Group for the Promotion of Pharmaceutical Chemistry in Academia (GP2A) held its 31st annual conference in August 2023 at the Faculty of Pharmacy of Aix-Marseille University, Marseille, France. There were 8 keynote presentations, 10 early career r
Externí odkaz:
https://doaj.org/article/31102bf7b86c4aaaa5206d2b658c0158
Publikováno v:
Molbank, Vol 2024, Iss 2, p M1825 (2024)
Plasmodium falciparum is a fast-evolving parasite responsible for the fatal disease malaria, making it crucial to renew our therapeutic arsenal. Modulating the artemisinin’s endoperoxide pharmacophore is a promising route to synthesizing new antima
Externí odkaz:
https://doaj.org/article/fdba7e1c3fef4ee09865f8399d0fb7ae
Autor:
Oscar Leonardo Avendaño Leon, Christophe Curti, Hussein El-Kashef, Youssef Kabri, Sébastien Redon, Patrice Vanelle
Publikováno v:
Molbank, Vol 2023, Iss 4, p M1750 (2023)
As part of our ongoing attempt to broaden the applications of the amidoxime moiety as a potential source of new antileishmanial agents, this study focuses on the product 4-(5-Benzyl-3-((4-fluorophenyl)sulfonyl)-5-methyl-4,5-dihydrofuran-2-yl)-2-nitro
Externí odkaz:
https://doaj.org/article/3a74bde867f145cfab83e73775a31ebd
Autor:
Oscar Leonardo Avendaño Leon, Christophe Curti, Fabiana Maia Santos Urbancg Moncorvo, Youssef Kabri, Sébastien Redon, Eduardo Caio Torres-Santos, Romain Paoli-Lombardo, Patrice Vanelle
Publikováno v:
Molbank, Vol 2023, Iss 4, p M1736 (2023)
As part of our ongoing research into the antileishmanial properties of amidoxime derivatives, we report a preliminary assessment of the antiparasitic properties of a novel compound, diethyl (5-benzyl-2-(4-(N′-hydroxycarbamimidoyl)phenyl)-5-methyl-4
Externí odkaz:
https://doaj.org/article/e55fadfa457e490a80ac0f4274d10c39
Autor:
Patrick Thevin, Christophe Curti, Alexandre Benech, Christophe Jean, Edouard Lamy, Caroline Castera Ducros, Nicolas Primas, Pierre Bertault-Peres, Patrice Vanelle
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0282164 (2023)
ObjectiveErythromycin is a macrolide antibiotic that is also prescribed off-label in premature neonates as a prokinetic agent. There is no oral formulation with dosage and/or excipients adapted for these high-risk patients.MethodsClinical studies of
Externí odkaz:
https://doaj.org/article/f97cb661961341bb8466362f7c3e1949
Autor:
Nicolas Primas, Guillaume Lano, Damien Brun, Christophe Curti, Marion Sallée, Emmanuelle Sampol-Manos, Edouard Lamy, Charleric Bornet, Stéphane Burtey, Patrice Vanelle
Publikováno v:
Pharmaceuticals, Vol 16, Iss 1, p 72 (2023)
Parenteral N-acetylcysteine has a wide variety of clinical applications, but its use can be limited by a poor chemical stability. We managed to control parenteral N-acetylcysteine stability, and to study the influence of additives on the decrease of
Externí odkaz:
https://doaj.org/article/d03a80ab525c40148c76b82a568fbfaf
Publikováno v:
Molecules, Vol 25, Iss 24, p 5922 (2020)
Anthracycline antibiotics play an important role in cancer chemotherapy. The need to improve their therapeutic index has stimulated an ongoing search for anthracycline analogs with enhanced properties. This review aims to summarize the common synthet
Externí odkaz:
https://doaj.org/article/00aad7044fd64129825e188ce642195b
Publikováno v:
Molecules, Vol 20, Iss 12, Pp 22890-22899 (2015)
Cross-coupling reactions between 2-methyl-2-propen-1-ol and various boronic acids are used to obtain aromatic-(2-methylallyl) derivatives. However, deboronation or isomerization side reactions may occur for several boronic acids. We describe herein t
Externí odkaz:
https://doaj.org/article/7cc921336e744a86898d2b2e3afaaa14
Publikováno v:
Molecules, Vol 18, Iss 4, Pp 4293-4307 (2013)
A convenient microwave irradiation protocol was utilized for the synthesis of b-ketosulfones 1–5 in good yields. These sulfones reacted with alkenes through a radical oxidative cyclization mediated by Mn(OAc)3. Dihydrofurans 6–10 were obtained in
Externí odkaz:
https://doaj.org/article/3055f51816c94e64abaf6df82e704c9d
Publikováno v:
Molecules, Vol 17, Iss 4, Pp 4313-4325 (2012)
A three step synthesis of various thiobarbiturate derivatives 17–24 was established. The first step is mediated by Mn(OAc)3, in order to generate a carbon-carbon bond between a terminal alkene and malonate. Derivatives 1–8 were obtained in modera
Externí odkaz:
https://doaj.org/article/483f77535afd41a7b89cb1decf14cba5