Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Christophe Côme"'
Publikováno v:
Haematologica, Vol 105, Iss 4 (2020)
Externí odkaz:
https://doaj.org/article/43f702ed159643b981159209b9848942
Autor:
Nkerorema Djodji Damas, Michela Marcatti, Christophe Côme, Lise Lotte Christensen, Morten Muhlig Nielsen, Roland Baumgartner, Helene Maria Gylling, Giulia Maglieri, Carsten Friis Rundsten, Stefan E. Seemann, Nicolas Rapin, Simon Thézenas, Søren Vang, Torben Ørntoft, Claus Lindbjerg Andersen, Jakob Skou Pedersen, Anders H. Lund
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Several lncRNAs have been linked to cancer. Here, the authors identify SNHG5 as a long non-coding RNA promoting proliferation and survival of colorectal cancer cells by protecting specific mRNAs from STAU1-mediated degradation.
Externí odkaz:
https://doaj.org/article/b798c3c5b5f543a9b6ab76d138075453
Autor:
Christophe Côme, Anna Cvrljevic, Mohd Moin Khan, Irina Treise, Thure Adler, Juan Antonio Aguilar-Pimentel, Byron Au-Yeung, Eleonora Sittig, Teemu Daniel Laajala, Yiling Chen, Sebastian Oeder, Julia Calzada-Wack, Marion Horsch, Tero Aittokallio, Dirk H Busch, Markus W Ollert, Frauke Neff, Johannes Beckers, Valerie Gailus-Durner, Helmut Fuchs, Martin Hrabě de Angelis, Zhi Chen, Riitta Lahesmaa, Jukka Westermarck
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152996 (2016)
The oncoprotein Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A) is overexpressed in most malignancies and is an obvious candidate target protein for future cancer therapies. However, the physiological importance of CIP2A-mediated PP2A inhibitio
Externí odkaz:
https://doaj.org/article/3fc34fe0c87f451793b1973405cb17a2
Autor:
Marion Horsch, Juan Antonio Aguilar-Pimentel, Clemens Bönisch, Christophe Côme, Cathrine Kolster-Fog, Klaus T Jensen, Anders H Lund, Icksoo Lee, Lawrence I Grossman, Christopher Sinkler, Maik Hüttemann, Erwin Bohn, Helmut Fuchs, Markus Ollert, Valérie Gailus-Durner, Martin Hrabĕ de Angelis, Johannes Beckers
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134503 (2015)
We established a selection strategy to identify new models for an altered airway inflammatory response from a large compendium of mutant mouse lines that were systemically phenotyped in the German Mouse Clinic (GMC). As selection criteria we included
Externí odkaz:
https://doaj.org/article/eb5e849edd9e468185aae4a588743bdb
Autor:
Mayssa Nassour, Ysia Idoux-Gillet, Abdelkader Selmi, Christophe Côme, Maria-Luisa M Faraldo, Marie-Ange Deugnier, Pierre Savagner
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53498 (2012)
Morphogenesis results from the coordination of distinct cell signaling pathways controlling migration, differentiation, apoptosis, and proliferation, along stem/progenitor cell dynamics. To decipher this puzzle, we focused on epithelial-mesenchymal t
Externí odkaz:
https://doaj.org/article/3d589e8e4a0f47cb99e9606b902aa77f
Autor:
Sami Ventelä, Christophe Côme, Juho-Antti Mäkelä, Robin M Hobbs, Leni Mannermaa, Markku Kallajoki, Edward K Chan, Pier Paolo Pandolfi, Jorma Toppari, Jukka Westermarck
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33209 (2012)
Protein phosphatase 2A (PP2A) is a critical regulator of protein serine/threonine phosphorylation. However, the physiological and developmental roles of different PP2A complexes are very poorly understood. Here, we show that a newly characterized PP2
Externí odkaz:
https://doaj.org/article/a847f782e16f47129e4d8dd52c24a522
Autor:
Eileen Wedge, Ulvi Ahmadov, Thomas B. Hansen, Zongliang Gao, Morten Tulstrup, Christophe Côme, Sridhar Nonavinkere Srivatsan, Tanzir Ahmed, Jakob S. Jespersen, Balthasar C. Schlotmann, Claudia Schöllkopf, Klas Raaschou-Jensen, Niels Ødum, Jørgen Kjems, Rasmus O. Bak, Matthew J. Walter, Kirsten Grønbæk, Lasse S. Kristensen
Publikováno v:
Wedge, E, Ahmadov, U, Hansen, T B, Gao, Z, Tulstrup, M, Côme, C, Nonavinkere Srivatsan, S, Ahmed, T, Jespersen, J S, Schlotmann, B C, Schöllkopf, C, Raaschou-Jensen, K, Ødum, N, Kjems, J, Bak, R O, Walter, M J, Grønbæk, K & Kristensen, L S 2023, ' Impact of U2AF1 mutations on circular RNA expression in myelodysplastic neoplasms ', Leukemia, vol. 37, no. 5, pp. 1113-1125 . https://doi.org/10.1038/s41375-023-01866-4
Mutations in U2AF1 are relatively common in myelodysplastic neoplasms (MDS) and are associated with an inferior prognosis, but the molecular mechanisms underlying this are not fully elucidated. Circular RNAs (circRNAs) have been implicated in cancer,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d552d18cfb6225451b91d289182d9379
https://pure.au.dk/portal/da/publications/impact-of-u2af1-mutations-on-circular-rna-expression-in-myelodysplastic-neoplasms(3de8bf0a-a973-4385-b2c9-1ac1bb734ed6).html
https://pure.au.dk/portal/da/publications/impact-of-u2af1-mutations-on-circular-rna-expression-in-myelodysplastic-neoplasms(3de8bf0a-a973-4385-b2c9-1ac1bb734ed6).html
Autor:
Jukka Westermarck, Simon Thézenas, Olli Kallioniemi, Jean-Marie Darbon, Jorma Isola, Johanna Ivaska, Jos Jonkers, Xiaoling Liu, Elina Mattila, Henrik Edgren, Maïa Chanrion, Anni Laine, Christophe Côme
Purpose: To investigate the clinical relevance of the recently characterized human oncoprotein cancerous inhibitor of protein phosphatase 2A (CIP2A) in human breast cancer.Experimental Design: CIP2A expression (mRNA and protein) was measured in three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1852f710829132c0ebaf02b65be784e2
https://doi.org/10.1158/1078-0432.c.6517930
https://doi.org/10.1158/1078-0432.c.6517930
Autor:
Pierre Savagner, Charles Theillet, Karl Friedrich Becker, Pascal De Santa Barbara, Frédéric Bibeau, Fabrice Magnino, Christophe Côme
Purpose: Carcinoma progression is linked to a partially dedifferentiated epithelial cell phenotype. As previously suggested, this regulation could involve transcription factors, Snail and Slug, known to promote epithelial-mesenchymal transitions duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304825b01ea8cf40939d58b8207b55fe
https://doi.org/10.1158/1078-0432.c.6518287.v1
https://doi.org/10.1158/1078-0432.c.6518287.v1
Supplementary Tables 2-3 from Snail and Slug Play Distinct Roles during Breast Carcinoma Progression
Autor:
Pierre Savagner, Charles Theillet, Karl Friedrich Becker, Pascal De Santa Barbara, Frédéric Bibeau, Fabrice Magnino, Christophe Côme
Supplementary Tables 2-3 from Snail and Slug Play Distinct Roles during Breast Carcinoma Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d278334b4791c9e8e4047088a048899
https://doi.org/10.1158/1078-0432.22441144
https://doi.org/10.1158/1078-0432.22441144