Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Christophe Chardonnens"'
Autor:
Luke Piggott, Noemie Luong, Frederic Massiere, Annett Kunze, Christophe Chardonnens, Anne Vaslin
Publikováno v:
Cancer Research. 83:6185-6185
Background: Glioblastoma (GBM) is one of the most aggressive and hard-to-treat cancers with a 5-year survival rate of 5.8%, in part due to the presence of the blood brain barrier (BBB) that prevents most therapeutics from reaching the tumors at effic
Autor:
Adam Treder, Gerald Gavory, Frank Burkamp, Robert M. Mader, Christophe Chardonnens, Tim Harrison, Grégoire Vuagniaux, Stefania Rigotti, Caroline Boyd, Frederic Massière, Colin O'Dowd, Anne Vaslin Chessex, Andrea Zaffalon, Astrid A. Glück
Publikováno v:
Cancer Research. 79:4423-4423
Background: The Wee1 tyrosine kinase is activated upon DNA damage and regulates the G2-M cell cycle checkpoint. Inhibition of Wee1, in conjunction with additional genetic alterations and/or addition of a DNA damaging agent, results in mitotic catastr