A Structural and Dynamic Analysis of the Partially Disordered Polymerase-Binding Domain in RSV Phosphoprotein

Autor: Christophe Cardone, Claire-Marie Caseau, Benjamin Bardiaux, Aurélien Thureaux, Marie Galloux, Monika Bajorek, Jean-François Eléouët, Marc Litaudon, François Bontems, Christina Sizun

Publikováno v: Biomolecules, Vol 11, Iss 8, p 1225 (2021)

The phosphoprotein P of Mononegavirales (MNV) is an essential co-factor of the viral RNA polymerase L. Its prime function is to recruit L to the ribonucleocapsid composed of the viral genome encapsidated by the nucleoprotein N. MNV phosphoproteins of

Externí odkaz: https://doaj.org/article/a64137b10a9842f4b354c6bf8f13e94c

Pneumoviral Phosphoprotein, a Multidomain Adaptor-Like Protein of Apparent Low Structural Complexity and High Conformational Versatility

Autor: Christina Sizun, Claire-Marie Caseau, Christophe Cardone, N. Pereira

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2021, 22 (4), pp.1537. ⟨10.3390/ijms22041537⟩
International Journal of Molecular Sciences, Vol 22, Iss 1537, p 1537 (2021)

Mononegavirales phosphoproteins (P) are essential co-factors of the viral polymerase by serving as a linchpin between the catalytic subunit and the ribonucleoprotein template. They have highly diverged, but their overall architecture is conserved. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a87b0c72c978088b0f9dc62dcffd16
https://hal.archives-ouvertes.fr/hal-03319031/file/ijms-22-01537-v2.pdf