Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Christophe, Vandier"'
Autor:
Sarah Proteau, Imène Krossa, Chrystel Husser, Maxime Guéguinou, Federica Sella, Karine Bille, Marie Irondelle, Mélanie Dalmasso, Thibault Barouillet, Yann Cheli, Céline Pisibon, Nicole Arrighi, Sacha Nahon-Estève, Arnaud Martel, Lauris Gastaud, Sandra Lassalle, Olivier Mignen, Patrick Brest, Nathalie M Mazure, Frédéric Bost, Stéphanie Baillif, Solange Landreville, Simon Turcotte, Dan Hasson, Saul Carcamo, Christophe Vandier, Emily Bernstein, Laurent Yvan-Charvet, Mitchell P Levesque, Robert Ballotti, Corine Bertolotto, Thomas Strub
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2262-2267 (2024)
Externí odkaz:
https://doaj.org/article/4674eb9ca9f241b4a3996ff03dc79709
Autor:
Alison Robert, David Crottès, Jérôme Bourgeais, Naig Gueguen, Arnaud Chevrollier, Jean-François Dumas, Stéphane Servais, Isabelle Domingo, Stéphanie Chadet, Julien Sobilo, Olivier Hérault, Thierry Lecomte, Christophe Vandier, William Raoul, Maxime Guéguinou
Publikováno v:
PLoS Biology, Vol 22, Iss 10, p e3002854 (2024)
The mitochondrial Ca2+ uniporter (MCU) plays crucial role in intramitochondrial Ca2+ uptake, allowing Ca2+-dependent activation of oxidative metabolism. In recent decades, the role of MCU pore-forming proteins has been highlighted in cancer. However,
Externí odkaz:
https://doaj.org/article/d921cf1a11eb48efbb81622c970372c0
Autor:
Marion Papin, Delphine Fontaine, Caroline Goupille, Sandy Figiel, Isabelle Domingo, Michelle Pinault, Cyrille Guimaraes, Nina Guyon, Pierre François Cartron, Patrick Emond, Antoine Lefevre, Maxime Gueguinou, David Crottès, Paul-Alain Jaffrès, Lobna Ouldamer, Karine Maheo, Gaëlle Fromont, Marie Potier-Cartereau, Philippe Bougnoux, Aurélie Chantôme, Christophe Vandier
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 5, Pp 100544- (2024)
SK3 channels are potassium channels found to promote tumor aggressiveness. We have previously demonstrated that SK3 is regulated by synthetic ether lipids, but the role of endogenous ether lipids is unknown. Here, we have studied the role of endogeno
Externí odkaz:
https://doaj.org/article/c60252b33184451bac3e20c91baf77d9
LKB1‐SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition
Autor:
Sarah Proteau, Imène Krossa, Chrystel Husser, Maxime Guéguinou, Federica Sella, Karine Bille, Marie Irondelle, Mélanie Dalmasso, Thibault Barouillet, Yann Cheli, Céline Pisibon, Nicole Arrighi, Sacha Nahon‐Estève, Arnaud Martel, Lauris Gastaud, Sandra Lassalle, Olivier Mignen, Patrick Brest, Nathalie M Mazure, Frédéric Bost, Stéphanie Baillif, Solange Landreville, Simon Turcotte, Dan Hasson, Saul Carcamo, Christophe Vandier, Emily Bernstein, Laurent Yvan‐Charvet, Mitchell P Levesque, Robert Ballotti, Corine Bertolotto, Thomas Strub
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-18 (2023)
Abstract Metastatic uveal melanomas are highly resistant to all existing treatments. To address this critical issue, we performed a kinome‐wide CRISPR‐Cas9 knockout screen, which revealed the LKB1‐SIK2 module in restraining uveal melanoma tumor
Externí odkaz:
https://doaj.org/article/1a3e75bad0684eebb8afbad93d505cd9
Autor:
Jifan Chen, Jean-Michel Escoffre, Oliver Romito, Tarik Iazourene, Antoine Presset, Marie Roy, Marie Potier Cartereau, Christophe Vandier, Yahua Wang, Guowei Wang, Pintong Huang, Ayache Bouakaz
Publikováno v:
Ultrasonics Sonochemistry, Vol 103, Iss , Pp 106768- (2024)
The blood–brain barrier (BBB) maintains brain homeostasis, regulates influx and efflux transport, and provides protection to the brain tissue. Ultrasound (US) and microbubble (MB)-mediated blood–brain barrier opening is an effective and safe tech
Externí odkaz:
https://doaj.org/article/2b8ba198d374417d9697a8f85d5a1e3e
Autor:
Saoussen Mlayah-Bellalouna, Dorra Aissaoui-Zid, Aurelie Chantome, Jed Jebali, Soumaya Souid, Emna Ayedi, Hafedh Mejdoub, Maya Belghazi, Naziha Marrakchi, Khadija Essafi-Benkhadir, Christophe Vandier, Najet Srairi-Abid
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The emerging concept of small conductance Ca2+-activated potassium channels (SKCa) as pharmacological target for cancer treatment has significantly increased in recent years. In this study, we isolated the P01 toxin from Androctonus australis (Aa) sc
Externí odkaz:
https://doaj.org/article/d4c991e53bfe45dea0b59b56dd54827c
Autor:
Debbie O'Reilly, Tim Downing, Sana Kouba, Marie Potier-Cartereau, Declan J. McKenna, Christophe Vandier, Paul Buchanan
Publikováno v:
Data in Brief, Vol 42, Iss , Pp 108143- (2022)
The data generated here in relates to the research article “CaV1.3 enhanced store operated calcium promotes resistance to androgen deprivation in prostate cancer”. A model of prostate cancer (PCa) progression to castration resistance was employed
Externí odkaz:
https://doaj.org/article/c960f9324a014268ae280a04722ca477
Autor:
Delphine Fontaine, Sandy Figiel, Romain Félix, Sana Kouba, Gaëlle Fromont, Karine Mahéo, Marie Potier-Cartereau, Aurélie Chantôme, Christophe Vandier
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 6, Pp 840-858 (2020)
Ether lipids (ELs) are lipids characterized by the presence of either an ether linkage (alkyl lipids) or a vinyl ether linkage [i.e., plasmalogens (Pls)] at the sn1 position of the glycerol backbone, and they are enriched in PUFAs at the sn2 position
Externí odkaz:
https://doaj.org/article/16e50e30cc084062977e19ccaa8d3a36
Autor:
Marjolaine Debant, Miguel Burgos, Patrice Hemon, Paul Buscaglia, Tinhinane Fali, Sarra Melayah, Nelig Le Goux, Christophe Vandier, Marie Potier-Cartereau, Jacques-Olivier Pers, Adrian Tempescul, Christian Berthou, Cristina Bagacean, Olivier Mignen, Yves Renaudineau
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Dysregulation in calcium (Ca2+) signaling is a hallmark of chronic lymphocytic leukemia (CLL). While the role of the B cell receptor (BCR) Ca2+ pathway has been associated with disease progression, the importance of the newly desc
Externí odkaz:
https://doaj.org/article/a5c66f1d9aee408ab699697673fab805
Autor:
Marion Papin, Cyrille Guimaraes, Benoit Pierre-Aue, Delphine Fontaine, Jeoffrey Pardessus, Hélène Couthon, Gaëlle Fromont, Karine Mahéo, Aurélie Chantôme, Christophe Vandier, Michelle Pinault
Publikováno v:
Marine Drugs, Vol 20, Iss 4, p 270 (2022)
Ether lipids are composed of alkyl lipids with an ether bond at the sn-1 position of a glycerol backbone and alkenyl lipids, which possess a vinyl ether bond at the sn-1 position of the glycerol. These ether glycerolipids are present either as polar
Externí odkaz:
https://doaj.org/article/29f58eb25dad4ae198c61c4bb4f13dd2