Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Christophe, Plisson"'
Autor:
Antonia A. Högnäsbacka, Alex J. Poot, Christophe Plisson, Jonas Bergare, David R. Bonsall, Stuart P. McCluskey, Lisa A. Wells, Esther Kooijman, Robert C. Schuit, Mariska Verlaan, Wissam Beaino, Guus A. M. S. van Dongen, Danielle J. Vugts, Charles S. Elmore, Jan Passchier, Albert D. Windhorst
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Background Mutations in the epidermal growth factor receptor (EGFR) kinase domain are common in non-small cell lung cancer. Conventional tyrosine kinase inhibitors target the mutation site in the ATP binding pocket, thereby inhibiting the re
Externí odkaz:
https://doaj.org/article/625cc69bf6ed4690bf32bf9fa866699c
Autor:
Sara Cesarec, Fraser Edgar, Titan Lai, Christophe Plisson, Andrew J. P. White, Philip W. Miller
Publikováno v:
Dalton Transactions. 51:5004-5008
A novel radiolabelling method exploiting 11C-dithiocarbamate ligands has been used to generate 11C-labelled Au(I), Au(III), Pd(II) and Pt(II) complexes in high radiochemical yields (71–99%). Labelled complexes were prepared in a rapid one-pot proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e5625dfcf6414b06350a6fe766b2be
https://doi.org/10.1039/d2dt00266c
https://doi.org/10.1039/d2dt00266c
Autor:
Brendon E. Cook, Jonathan Archbold, Khaled Nasr, Sara Girmay, Stanley I. Goldstein, Pei Li, Sivaraman Dandapani, Nathan E. Genung, Sac-Pham Tang, Stuart McClusky, Christophe Plisson, Megan E. Afetian, Chrissa A. Dwyer, Michael Fazio, William J. Drury, Frank Rigo, Laurent Martarello, Maciej Kaliszczak
Publikováno v:
Molecular imaging and biology. 24(6)
The treatment of complex neurological diseases often requires the administration of large therapeutic drugs, such as antisense oligonucleotide (ASO), by lumbar puncture into the intrathecal space in order to bypass the blood-brain barrier. Despite th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e72f918165f8a07d9d8a09a98a8da8
https://pubmed.ncbi.nlm.nih.gov/35655109
https://pubmed.ncbi.nlm.nih.gov/35655109
Autor:
Christophe Plisson, Lisa Wells, Christine A. Parker, Mayca Onega, Sara Moz, Nicholas Keat, Christopher Coello, Pauline T. Lukey, Giovanni Vitulli, Joaquim Ramada-Magalhaes, Roger N. Gunn, Frederick J. Wilson, Sharon Ashworth, Robert J. Slack, Sac-Pham Tang, Gaia Rizzo, Jan Passchier
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
PurposeIntegrin αvβ6belongs to the RGD subset of the integrin family, and its expression levels are a prognostic and theranostic factor in some types of cancer and pulmonary fibrosis. This paper describes the GMP radiolabelling of the synthetic 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0df9d47daff9ba4eabf23c6dbb7f6ff
http://europepmc.org/articles/PMC7075836
http://europepmc.org/articles/PMC7075836
Autor:
Antonia Högnäsbacka, Alex Poot, Christophe Plisson, Jonas Bergare, Stuart McCluskey, David Bonsall, Lisa Wells, Esther Kooijman, Robert Schuit, Mariska Verlaan, Wissam Beaino, Guus van Dongen, Danielle Vugts, Charles Elmore, Jan Passchier, Albert Windhorst
Publikováno v:
Nuclear Medicine and Biology. :S38-S39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::851f0f2a177c5374d9e861847cce7938
https://doi.org/10.1016/s0969-8051(22)00116-0
https://doi.org/10.1016/s0969-8051(22)00116-0
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Purpose A limit on developing new treatments for a number of central nervous system (CNS) disorders has been the inadequate understanding of the in vivo pathophysiology underlying neurological and psychiatric disorders and the lack of in vivo tools t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2448b0c51334f3c3ab0dca847270dad2
http://europepmc.org/articles/PMC6974496
http://europepmc.org/articles/PMC6974496
Publikováno v:
The Scientific World Journal, Vol 2014 (2014)
In early drug development advanced imaging techniques can help with progressing new molecular entities (NME) to subsequent phases of drug development and thus reduce attrition. However, several organizational, operational, and regulatory hurdles pose
Externí odkaz:
https://doaj.org/article/8cac48af1cc64db2aacdecff953a3516
Autor:
Stefan Verhoog, Thomas C. Wilson, Jane K. Sosabowski, Véronique Gouverneur, Giulia Boscutti, Christophe Plisson, Florian Guibbal, Jan Passchier, Sharon Ashworth, Mateusz Imiołek, Michael J. Tilby, Sven Macholl, Benjamin G. Davis, Choon Wee Kee, Adeline W. J. Poh, Bart Cornelissen, Osman Tack, Juliette Chupin, Michael C. Willis, Patrick G. Isenegger, Roxana Kashani
Publikováno v:
Journal of the American Chemical Society
18F labeling strategies for unmodified peptides with [18F]fluoride require 18F-labeled prosthetics for bioconjugation more often with cysteine thiols or lysine amines. Here we explore selective radical chemistry to target aromatic residues applying C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f60d872f41e1bd20012b9a66063f12
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Christophe Plisson, Kurt R. Auger, Matthew Williams, Yvonne Lewis, Sarah P. Blagden, Azeem Saleem, Jerry M. Tolson, Ronald A. Fleming, Li Yan, Nicholas F Brown, Laurie Lenox, Hendrik-Tobias Arkenau, Rajendra P. Singh, Graham E. Searle, Paul Mulholland, Jianping Zhang, David Cox
Publikováno v:
Neuro-Oncology. 20:1634-1642
Background GSK2256098 is a novel oral focal adhesion kinase (FAK) inhibitor. Preclinical studies demonstrate growth inhibition in glioblastoma cell lines. However, rodent studies indicate limited blood–brain barrier (BBB) penetration. In this expan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31dbaea36402f534744fadb8cdd1f456
https://doi.org/10.1093/neuonc/noy078
https://doi.org/10.1093/neuonc/noy078
Autor:
Anna Haslop, Richard Southworth, Edward W. Tate, Christophe Plisson, Christopher Coello, Nicholas J. Long, Roger N. Gunn, Stuart P. McCluskey, Lisa Wells
Publikováno v:
McCluskey, S, Haslop, A, Coello, C, Gunn, R, Tate, E, Southworth, R, Plisson, C, Long, N J & Wells, L 2019, ' Imaging of chemotherapy-induced acute cardiotoxicity with 18 F-labeled lipophilic cations ', Journal of Nuclear Medicine, vol. 60, no. 12, pp. 1750-1756 . https://doi.org/10.2967/jnumed.119.226787
Many chemotherapy agents are toxic to the heart, such that increasing numbers of cancer survivors are now living with the potentially lethal cardiovascular consequences of their treatment. Earlier and more sensitive detection of chemotherapy-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1d828010812d7ded0cdd8abcc4c28d
https://kclpure.kcl.ac.uk/en/publications/b4c0879c-aa46-4956-b532-727c00be5e69
https://kclpure.kcl.ac.uk/en/publications/b4c0879c-aa46-4956-b532-727c00be5e69
