Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Christophe, Jung"'
Autor:
Markus Matthias Hohle, Katja Lammens, Fabian Gut, Bingzhi Wang, Sophia Kahler, Kathrin Kugler, Michael Till, Roland Beckmann, Karl-Peter Hopfner, Christophe Jung
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract While recent technological developments contributed to breakthrough advances in single particle cryo-electron microscopy (cryo-EM), sample preparation remains a significant bottleneck for the structure determination of macromolecular complex
Externí odkaz:
https://doaj.org/article/63856b0cc1234d46a17152757c8a1f1f
Autor:
Zhan Qi, Christophe Jung, Peter Bandilla, Claudia Ludwig, Mark Heron, Anja Sophie Kiesel, Mariam Museridze, Julia Philippou‐Massier, Miroslav Nikolov, Alessio Renna Max Schnepf, Ulrich Unnerstall, Stefano Ceolin, Bettina Mühlig, Nicolas Gompel, Johannes Soeding, Ulrike Gaul
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 2, Pp 1-26 (2022)
Abstract The core promoter plays a central role in setting metazoan gene expression levels, but how exactly it “computes” expression remains poorly understood. To dissect its function, we carried out a comprehensive structure–function analysis
Externí odkaz:
https://doaj.org/article/1a921a416e01438aa5f2ba5d3fbc8538
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Necroptosis is a form of regulated cell death that can occur downstream of several immune pathways. While previous studies have shown that dysregulated necroptosis can lead to strong inflammatory responses, little is known about the identity of the e
Externí odkaz:
https://doaj.org/article/739a8010fe594f41a926b8b85a43e891
Autor:
Xiaoling Li, Richard Fetter, Tina Schwabe, Christophe Jung, Liren Liu, Hermann Steller, Ulrike Gaul
Publikováno v:
eLife, Vol 10 (2021)
The blood–brain barrier (BBB) of Drosophila comprises a thin epithelial layer of subperineural glia (SPG), which ensheath the nerve cord and insulate it against the potassium-rich hemolymph by forming intercellular septate junctions (SJs). Previous
Externí odkaz:
https://doaj.org/article/1a4165662da7452f9862cb4dcd70373d
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101694- (2020)
Summary: An essential event in gene regulation is the binding of a transcription factor (TF) to its target DNA. Models considering the interactions between the TF and the DNA geometry proved to be successful approaches to describe this binding event,
Externí odkaz:
https://doaj.org/article/1b38da966e3646fabf2d9bbd8f579b0c
Autor:
Max Schnepf, Claudia Ludwig, Peter Bandilla, Stefano Ceolin, Ulrich Unnerstall, Christophe Jung, Ulrike Gaul
Publikováno v:
iScience, Vol 23, Iss 2, Pp - (2020)
Summary: The DNA of eukaryotes is wrapped around histone octamers to form nucleosomes. Although it is well established that the DNA sequence significantly influences nucleosome formation, its precise contribution has remained controversial, partially
Externí odkaz:
https://doaj.org/article/bbd6d83328ff4c26acd7c9a7fad8a478
Autor:
Christophe Jung, Peter Bandilla, Marc von Reutern, Max Schnepf, Susanne Rieder, Ulrich Unnerstall, Ulrike Gaul
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Methods to measure selective transcription factor-DNA binding often lack sensitivity and are not performed in solution. Here the authors develop a method to perform fluorescence anisotropy measurements of transcription factor-DNA binding energies wit
Externí odkaz:
https://doaj.org/article/6de05cf9c14c415c94eeb469a7b93565
Autor:
Christophe Jung, Peter Bandilla, Marc von Reutern, Max Schnepf, Susanne Rieder, Ulrich Unnerstall, Ulrike Gaul
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
In the original version of this Article, equation three contained a sign error whereby the term RT was added when it should have been subtracted. This has now been corrected in the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/39829594b078435395f55108c898a65e
Autor:
Matthias Rotheneder, Kristina Stakyte, Erik van de Logt, Joseph D. Bartho, Katja Lammens, Yilan Fan, Aaron Alt, Brigitte Kessler, Christophe Jung, Wynand P. Roos, Barbara Steigenberger, Karl-Peter Hopfner
Publikováno v:
Molecular cell.
The DNA double-strand break repair complex Mre11-Rad50-Nbs1 (MRN) detects and nucleolytically processes DNA ends, activates the ATM kinase, and tethers DNA at break sites. How MRN can act both as nuclease and scaffold protein is not well understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f3c70745071e89e895869338498304
https://pubmed.ncbi.nlm.nih.gov/36577401
https://pubmed.ncbi.nlm.nih.gov/36577401
A sensitive mNeonGreen reporter system to measure transcriptional dynamics in Drosophila development
Autor:
Stefano, Ceolin, Monika, Hanf, Marta, Bozek, Andrea Ennio, Storti, Nicolas, Gompel, Ulrich, Unnerstall, Christophe, Jung, Ulrike, Gaul
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Communications Biology
Communications Biology
The gene regulatory network governing anterior–posterior axis formation in Drosophila is a well-established paradigm to study transcription in developmental biology. The rapid temporal dynamics of gene expression during early stages of development,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0356bfa5f03f613f97b39d211c85a854
http://link.springer.com/article/10.1038/s42003-020-01375-5
http://link.springer.com/article/10.1038/s42003-020-01375-5