Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Christoph Seger"'
Publikováno v:
Cells, Vol 12, Iss 2, p 329 (2023)
Screening for possible interferences from steroidal compounds other than the target analytes (endogenous or exogenous) is well established in LC-MS/MS assay development for steroid quantification in a routine clinical setting. However, interferences
Externí odkaz:
https://doaj.org/article/2d9c7f8b52c441d39b47c67277b5c6ff
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14691 (2022)
Steroid analysis in clinical laboratories is dominated by immunoassays (IAs) that have a high sample turnover but are inherently limited in trueness, precision, and sensitivity. Liquid chromatography coupled to mass spectrometry (LC-MS/MS) has proved
Externí odkaz:
https://doaj.org/article/96045339187b4fda8caafa383edc1df5
Autor:
Christoph Seger, Sonja Sturm
Publikováno v:
Cells, Vol 11, Iss 21, p 3526 (2022)
Gaining structural information is a must to allow the unequivocal structural characterization of analytes from natural sources. In liquid state, NMR spectroscopy is almost the only possible alternative to HPLC-MS and hyphenating the effluent of an an
Externí odkaz:
https://doaj.org/article/c57d8f2bd07843f1bc3da216ea6452a9
Publikováno v:
Metabolites, Vol 11, Iss 8, p 529 (2021)
By combining HPLC-DAD-QTOF-MS and HPLC-SPE-NMR, the in vitro metabolism of vitetrifolin D, a pharmacologically active key molecule from Vitex agnus-castus in liver cell fractions, was investigated. Twenty-seven phase I and phase II metabolites were t
Externí odkaz:
https://doaj.org/article/fdd403b97036485086e2f38a75937e0b
Autor:
Martin Risch, Marc Kovac, Corina Risch, Dorothea Hillmann, Michael Ritzler, Nadia Wohlwend, Thomas Lung, Michael Allmann, Christoph Seger, Lorenz Risch
Publikováno v:
Data, Vol 5, Iss 4, p 105 (2020)
Although SARS-CoV-2 antibody assays have been found to provide valid results in EDTA-anticoagulated whole blood, so far, they have not demonstrated that antibody levels in whole blood originating from capillary blood samples are comparable to antibod
Externí odkaz:
https://doaj.org/article/eab0d83a90b34b58995c91bc039b0507
Publikováno v:
Journal of Agricultural and Food Chemistry. 70:7586-7593
Autor:
Anja Kobel, Tobias Schierscher, Neeraj Singh, Linda Salzmann, Franziska Liesch, Friederike Bauland, Andrea Geistanger, Lorenz Risch, Christian Geletneky, Christoph Seger, Judith Taibon
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM).
Objectives To develop an isotope dilution-liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based candidate reference measurement procedure (RMP) for levetiracetam quantification in human serum and plasma. Methods Quantitative nuclear magneti
Autor:
Linda Salzmann, Janik Wild, Neeraj Singh, Tobias Schierscher, Franziska Liesch, Friederike Bauland, Andrea Geistanger, Lorenz Risch, Christian Geletneky, Christoph Seger, Judith Taibon
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM).
Objectives To describe and validate a reference measurement procedure (RMP) for gabapentin, employing quantitative nuclear magnetic resonance (qNMR) spectroscopy to determine the absolute content of the standard materials in combination with isotope
Publikováno v:
Clinical chemistry and laboratory medicineReferences.
For molecules that can be well described metrologically in the sense of the definition of measurands, and which can also be recorded analytically as individual substances, reference measurement service traceability to a metrologically sound foundatio
Autor:
Hermann Stuppner, Regina Gruber, Nora Gibitz-Eisath, Sonja Sturm, Christoph Seger, Miriam Eichberger
Publikováno v:
Journal of Separation Science
This report presents the first ultra high performance supercritical fluid chromatography diode array detector based assay for simultaneous determination of iridoid glucosides, flavonoid glucuronides, and phenylpropanoid glycosides in Verbena officina