Increased innate immune responses in adolescents with obesity and its relation to subclinical cardiovascular measures: An exploratory study

Autor: Siroon Bekkering, Christoph Saner, Boris Novakovic, Toby Mansell, Danielle K. Longmore, Zoe McCallum, Anne-Louise Ponsonby, Markus Juonala, Mihai G. Netea, Matthew A. Sabin, Richard Saffery, Niels P. Riksen, David P. Burgner

Publikováno v: iScience, Vol 27, Iss 5, Pp 109762- (2024)

Summary: Cardiometabolic risk accrues across the life course and childhood and adolescence are key periods for effective prevention. Obesity is associated with inflammation in adults, but pediatric data are scarce. In a cross-sectional and longitudin

Externí odkaz: https://doaj.org/article/18ea2a93c6124c2c9822b1d8f3285792

Changes in preterm birth and stillbirth during COVID-19 lockdowns in 26 countries

Autor: Clara Calvert, Meredith Brockway, Helga Zoega, Jessica E. Miller, Jasper V. Been, Adeladza Kofi Amegah, Amy Racine-Poon, Solmaz Eradat Oskoui, Ishaya I. Abok, Nima Aghaeepour, Christie D. Akwaowo, Belal N. Alshaikh, Adejumoke I. Ayede, Fabiana Bacchini, Behzad Barekatain, Rodrigo Barnes, Karolina Bebak, Anick Berard, Zulfiqar A. Bhutta, Jeffrey R. Brook, Lenroy R. Bryan, Kim N. Cajachagua-Torres, Marsha Campbell-Yeo, Dinh-Toi Chu, Kristin L. Connor, Luc Cornette, Sandra Cortés, Mandy Daly, Christian Debauche, Iyabode Olabisi F. Dedeke, Kristjana Einarsdóttir, Hilde Engjom, Guadalupe Estrada-Gutierrez, Ilaria Fantasia, Nicole M. Fiorentino, Meredith Franklin, Abigail Fraser, Onesmus W. Gachuno, Linda A. Gallo, Mika Gissler, Siri E. Håberg, Abbas Habibelahi, Jonas Häggström, Lauren Hookham, Lisa Hui, Luis Huicho, Karen J. Hunter, Sayeeda Huq, Ashish KC, Seilesh Kadambari, Roya Kelishadi, Narjes Khalili, Joanna Kippen, Kirsty Le Doare, Javier Llorca, Laura A. Magee, Maria C. Magnus, Kenneth K. C. Man, Patrick M. Mburugu, Rishi P. Mediratta, Andrew D. Morris, Nazeem Muhajarine, Rachel H. Mulholland, Livia Nagy Bonnard, Victoria Nakibuuka, Natasha Nassar, Sylvester D. Nyadanu, Laura Oakley, Adesina Oladokun, Oladapo O. Olayemi, Olanike A. Olutekunbi, Rosena O. Oluwafemi, Taofik O. Ogunkunle, Chris Orton, Anne K. Örtqvist, Joseph Ouma, Oyejoke Oyapero, Kirsten R. Palmer, Lars H. Pedersen, Gavin Pereira, Isabel Pereyra, Roy K. Philip, Dominik Pruski, Marcin Przybylski, Hugo G. Quezada-Pinedo, Annette K. Regan, Natasha R. Rhoda, Tonia A. Rihs, Taylor Riley, Thiago Augusto Hernandes Rocha, Daniel L. Rolnik, Christoph Saner, Francisco J. Schneuer, Vivienne L. Souter, Olof Stephansson, Shengzhi Sun, Emma M. Swift, Miklós Szabó, Marleen Temmerman, Lloyd Tooke, Marcelo L. Urquia, Peter von Dadelszen, Gregory A. Wellenius, Clare Whitehead, Ian C. K. Wong, Rachael Wood, Katarzyna Wróblewska-Seniuk, Kojo Yeboah-Antwi, Christopher S. Yilgwan, Agnieszka Zawiejska, Aziz Sheikh, Natalie Rodriguez, David Burgner, Sarah J. Stock, Meghan B. Azad

Publikováno v: Calvert, C, Brockway, M, Zoega, H, Miller, J E, Been, J V, Amegah, A K, Racine-Poon, A, Oskoui, S E, Abok, I I, Aghaeepour, N, Akwaowo, C D, Alshaikh, B N, Ayede, A I, Bacchini, F, Barekatain, B, Barnes, R, Bebak, K, Berard, A, Bhutta, Z A, Brook, J R, Bryan, L R, Cajachagua-Torres, K N, Campbell-Yeo, M, Chu, D-T, Connor, K L, Cornette, L, Cortés, S, Daly, M, Debauche, C, Dedeke, I O F, Einarsdóttir, K, Engjom, H, Estrada-Gutierrez, G, Fantasia, I, Fiorentino, N M, Franklin, M, Fraser, A, Gachuno, O W, Gallo, L A, Gissler, M, Håberg, S E, Habibelahi, A, Häggström, J, Hookham, L, Hui, L, Huicho, L, Hunter, K J, Huq, S, Kc, A, Kadambari, S, Kelishadi, R, Khalili, N, Kippen, J, Le Doare, K, Llorca, J, Magee, L A, Magnus, M C, Man, K K C, Mburugu, P M, Mediratta, R P, Morris, A D, Muhajarine, N, Mulholland, R H, Bonnard, L N, Nakibuuka, V, Nassar, N, Nyadanu, S D, Oakley, L, Oladokun, A, Olayemi, O O, Olutekunbi, O A, Oluwafemi, R O, Ogunkunle, T O, Orton, C, Örtqvist, A K, Ouma, J, Oyapero, O, Palmer, K R, Pedersen, L H, Pereira, G, Pereyra, I, Philip, R K, Pruski, D, Przybylski, M, Quezada-Pinedo, H G, Regan, A K, Rhoda, N R, Rihs, T A, Riley, T, Rocha, T A H, Rolnik, D L, Saner, C, Schneuer, F J, Souter, V L, Stephansson, O, Sun, S, Swift, E M, Szabó, M, Temmerman, M, Tooke, L, Urquia, M L, von Dadelszen, P, Wellenius, G A, Whitehead, C, Wong, I C K, Wood, R, Wróblewska-Seniuk, K, Yeboah-Antwi, K, Yilgwan, C S, Zawiejska, A, Sheikh, A, Rodriguez, N, Burgner, D, Stock, S J & Azad, M B 2023, ' Changes in preterm birth and stillbirth during COVID-19 lockdowns in 26 countries ', Nature Human Behaviour . https://doi.org/10.1038/s41562-023-01522-y
Calvert, C, Brockway, M, Zoega, H, Miller, J E, Been, J V, Amegah, A K, Racine-Poon, A, Oskoui, S E, Abok, I I, Aghaeepour, N, Akwaowo, C D, Alshaikh, B N, Ayede, A I, Bacchini, F, Barekatain, B, Barnes, R, Bebak, K, Berard, A, Bhutta, Z A, Brook, J R, Bryan, L R, Cajachagua-Torres, K N, Campbell-Yeo, M, Chu, D T, Connor, K L, Cornette, L, Cortés, S, Daly, M, Debauche, C, Dedeke, I O F, Einarsdóttir, K, Engjom, H, Estrada-Gutierrez, G, Fantasia, I, Fiorentino, N M, Franklin, M, Fraser, A, Gachuno, O W, Gallo, L A, Gissler, M, Håberg, S E, Habibelahi, A, Häggström, J, Hookham, L, Hui, L, Huicho, L, Hunter, K J, Huq, S, Kc, A, Kadambari, S, Kelishadi, R, Khalili, N, Kippen, J, Le Doare, K, Llorca, J, Magee, L A, Magnus, M C, Man, K K C, Mburugu, P M, Mediratta, R P, Morris, A D, Muhajarine, N, Mulholland, R H, Bonnard, L N, Nakibuuka, V, Nassar, N, Nyadanu, S D, Oakley, L, Oladokun, A, Olayemi, O O, Olutekunbi, O A, Oluwafemi, R O, Ogunkunle, T O, Orton, C, Örtqvist, A K, Ouma, J, Oyapero, O, Palmer, K R, Pedersen, L H, Pereira, G, Pereyra, I, Philip, R K, Pruski, D, Przybylski, M, Quezada-Pinedo, H G, Regan, A K, Rhoda, N R, Rihs, T A, Riley, T, Rocha, T A H, Rolnik, D L, Saner, C, Schneuer, F J, Souter, V L, Stephansson, O, Sun, S, Swift, E M, Szabó, M, Temmerman, M, Tooke, L, Urquia, M L, von Dadelszen, P, Wellenius, G A, Whitehead, C, Wong, I C K, Wood, R, Wróblewska-Seniuk, K, Yeboah-Antwi, K, Yilgwan, C S, Zawiejska, A, Sheikh, A, Rodriguez, N, Burgner, D, Stock, S J & Azad, M B 2023, ' Changes in preterm birth and stillbirth during COVID-19 lockdowns in 26 countries ', Nature Human Behaviour, vol. 7, no. 4, pp. 529-544 . https://doi.org/10.1038/s41562-023-01522-y
Nature Human Behaviour, 7(4), 529-544. Nature Publishing Group
Calvert, Clara; Brockway, Meredith Merilee; Zoega, Helga; Miller, Jessica E; Been, Jasper V; Amegah, Adeladza Kofi; Racine-Poon, Amy; Oskoui, Solmaz Eradat; Abok, Ishaya I; Aghaeepour, Nima; Akwaowo, Christie D; Alshaikh, Belal N; Ayede, Adejumoke I; Bacchini, Fabiana; Barekatain, Behzad; Barnes, Rodrigo; Bebak, Karolina; Berard, Anick; Bhutta, Zulfiqar A; Brook, Jeffrey R; ... (2023). Changes in preterm birth and stillbirth during COVID-19 lockdowns in 26 countries. Nature human behaviour, 7(4), pp. 529-544. Springer Nature 10.1038/s41562-023-01522-y
iPOP Study Team 2023, ' Changes in preterm birth and stillbirth during COVID-19 lockdowns in 26 countries ', Nature Human Behaviour . https://doi.org/10.1038/s41562-023-01522-y
Nature Human Behaviour
Calvert, C, Brockway, M, Zoega, H, Miller, J E, Been, J V, Amegah, A K, Eradat Oskoui, S, Hunter, K, Mulholland, R, Wood, R, Sheikh, A & Stock, S J 2023, ' Changes in preterm birth and stillbirth during COVID-19 lockdowns in 26 countries ', Nature Human Behaviour, vol. 7, no. 4, pp. 529-544 . https://doi.org/10.1038/s41562-023-01522-y

Preterm birth (PTB) is the leading cause of infant mortality worldwide. Changes in PTB rates, ranging from −90% to +30%, were reported in many countries following early COVID-19 pandemic response measures (‘lockdowns’). It is unclear whether th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87776f22c6c73a6f30ce6fa4813fd0d
https://pure.au.dk/portal/da/publications/changes-in-preterm-birth-and-stillbirth-during-covid19-lockdowns-in-26-countries(a3451e24-eb9c-4dc0-93c3-13267f037c4a).html

Lower grip strength in youth with obesity identifies those with increased cardiometabolic risk

Autor: Matthew A. Sabin, Tomi T. Laitinen, David Burgner, Brooklyn J Fraser, Joel Nuotio, Costan G. Magnussen, Brooke E. Harcourt, Christoph Saner, Markus Juonala

Publikováno v: Obesity Research & Clinical Practice. 14:286-289

Background We examined whether grip strength differentiates youth with obesity with increased cardiometabolic risk. Methods The sample comprised 43 youth with severe obesity (mean age 14.8, standard deviation 3.0 years) enrolled in the Childhood Over

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb586d304930560283eb38432a95c277
https://doi.org/10.1016/j.orcp.2020.04.004

Impact of Type 1 Diabetes Mellitus on Bone Health in Children

Autor: Christoph Saner, Marco Janner

Publikováno v: Hormone research in paediatrics. 95(3)

This paper gives an overview of the impact of type 1 diabetes on bone health in children and adolescents. Firstly, we analyse studies using dual X-ray absorptiometry to assess bone mineral content and bone mineral density. Then, we discuss modern, no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32eeca931b3b0bf9b020c78947fa7cb6
https://pubmed.ncbi.nlm.nih.gov/34937025

1145Obesity-related changes in metabolomic profiles in youth

Autor: Zoe McCallum, Toby Mansell, Markus Juonala, Matthew A. Sabin, Christoph Saner, David Burgner

Publikováno v: International Journal of Epidemiology. 50

Background Obesity during childhood and adolescence is linked to subclinical atherosclerosis, metabolic dysfunction and later cardiovascular disease. Adults with obesity have metabolomic profiles that predict cardiovascular disease and mortality. Ana

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c6bede00abfac38226d5121afc78b9e
https://doi.org/10.1093/ije/dyab168.416