Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Christoph S.N. Klose"'
Autor:
Manuel O. Jakob, Daniel Spari, Daniel Sànchez Taltavull, Lilian Salm, Bahtiyar Yilmaz, Rémi Doucet Ladevèze, Catherine Mooser, David Pereyra, Ye Ouyang, Theresa Schmidt, Irene Mattiola, Patrick Starlinger, Deborah Stroka, Franziska Tschan, Daniel Candinas, Georg Gasteiger, Christoph S.N. Klose, Andreas Diefenbach, Mercedes Gomez de Agüero, Guido Beldi
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112269- (2023)
Summary: It is generally believed that environmental or cutaneous bacteria are the main origin of surgical infections. Therefore, measures to prevent postoperative infections focus on optimizing hygiene and improving asepsis and antisepsis. In a larg
Externí odkaz:
https://doaj.org/article/c73c0b7cf4aa4763ab2085992ed320f3
Autor:
Coco Chu, Saya Moriyama, Zhi Li, Lei Zhou, Anne-Laure Flamar, Christoph S.N. Klose, Jesper B. Moeller, Gregory G. Putzel, David R. Withers, Gregory F. Sonnenberg, David Artis
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3750-3758 (2018)
Summary: The intestinal tract is constantly exposed to various stimuli. Group 3 innate lymphoid cells (ILC3s) reside in lymphoid organs and in the intestinal tract and are required for immunity to enteric bacterial infection. However, the mechanisms
Externí odkaz:
https://doaj.org/article/17a683962d514b848b39055c6bff9d9d
Autor:
Miguel Gonzalez Acera, Marvin Bubeck, Fabrizio Mascia, Leonard Diemand, Gregor Sturm, Anja A. Kühl, Raja Atreya, Dieter Chichung Lie, Markus F. Neurath, Michael Schumann, Christoph S.N. Klose, Zlatko Trajanoski, Christoph Becker, Jay V. Patankar
Publikováno v:
Cells, Vol 10, Iss 9, p 2253 (2021)
Inflammatory bowel diseases (IBD) are characterized by chronic dysregulation of immune homeostasis, epithelial demise, immune cell activation, and microbial translocation. Each of these processes leads to proinflammatory changes via the release of cy
Externí odkaz:
https://doaj.org/article/d6eddfb12d2f4f189d75b176b637e8f1
Autor:
Caroline Tizian, Fabian Schumacher, Konrad Gronke, Michael Kofoed-Branzk, Lukas Amann, Antigoni Triantafyllopoulou, Fabian Guendel, Mario Witkowski, Christoph S.N. Klose, Pedro P. Hernandez, Jakob Zimmermann, Hansruedi Glatt, Andreas Diefenbach
Publikováno v:
Nature
Environmental genotoxic factors pose a challenge to the genomic integrity of epithelial cells at barrier surfaces that separate host organisms from the environment. They can induce mutations that, if they occur in epithelial stem cells, contribute to
Autor:
Johannes Steffen, Stefanie Ehrentraut, Ute Bank, Aindrila Biswas, Caio Andreeta Figueiredo, Oliver Hölsken, Henning Peter Düsedau, Vladyslava Dovhan, Laura Knop, Jacqueline Thode, Silvina Romero-Suárez, Carmen Infante Duarte, Jason Gigley, Chiara Romagnani, Andreas Diefenbach, Christoph S.N. Klose, Thomas Schüler, Ildiko Rita Dunay
Publikováno v:
Cell Reports. 38:110564
Cerebral infections are restrained by a complex interplay of tissue-resident and recruited peripheral immune cells. Whether innate lymphoid cells (ILCs) are involved in the orchestration of the neuroinflammatory dynamics is not fully understood. Here
Autor:
Zhengxiang He, Wen Zhang, Saya Moriyama, Sergio A. Lira, Jesper B. Moeller, Christoph S.N. Klose, David Artis, Lucille C. Rankin, Lili Chen, Anne-Laure Flamar, Nicholas J. Bessman, Gerard Karsenty, Gregory G. Putzel, Vladislava Stokic-Trtica, Tanel Mahlakõiv, Hans Reimer Rodewald
Publikováno v:
Immunity
Flamar, A L, Klose, C S N, Moeller, J B, Mahlakõiv, T, Bessman, N J, Zhang, W, Moriyama, S, Stokic-Trtica, V, Rankin, L C, Putzel, G G, Rodewald, H R, He, Z, Chen, L, Lira, S A, Karsenty, G & Artis, D 2020, ' Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity ', Immunity, vol. 52, no. 4, pp. 606-619.e6 . https://doi.org/10.1016/j.immuni.2020.02.009
Flamar, A L, Klose, C S N, Moeller, J B, Mahlakõiv, T, Bessman, N J, Zhang, W, Moriyama, S, Stokic-Trtica, V, Rankin, L C, Putzel, G G, Rodewald, H R, He, Z, Chen, L, Lira, S A, Karsenty, G & Artis, D 2020, ' Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity ', Immunity, vol. 52, no. 4, pp. 606-619.e6 . https://doi.org/10.1016/j.immuni.2020.02.009
Group 2 innate lymphoid cells (ILC2s) regulate immunity, inflammation, and tissue homeostasis. Two distinct subsets of ILC2s have been described: steady-state natural ILC2s and inflammatory ILC2s, which are elicited following helminth infection. Howe
Autor:
David Rafei-Shamsabadi, Karolina Ebert, Yakup Tanriver, Stefan F. Martin, Sebastian J. Arnold, Saskia van de Poel, Christoph S.N. Klose, Britta Dorn, Andreas Diefenbach, Timotheus Y.F. Halim, Thilo Jakob, Andrew N. J. McKenzie, Stefanie Kunz
Publikováno v:
The Journal of Investigative Dermatology
Allergic contact dermatitis and its animal model, contact hypersensitivity, are T-cell-mediated inflammatory skin diseases that require activation of the innate immune system. Here we investigate the role of innate lymphoid cells (ILCs) during the el
Autor:
David R. Withers, Anne-Laure Flamar, David Artis, Gregory F. Sonnenberg, Lei Zhou, Christoph S.N. Klose, Jesper B. Moeller, Saya Moriyama, Gregory G. Putzel, Zhi Li, Coco Chu
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3750-3758 (2018)
Chu, C, Moriyama, S, Li, Z, Zhou, L, Flamar, A L, Klose, C S N, Moeller, J B, Putzel, G G, Withers, D R, Sonnenberg, G F & Artis, D 2018, ' Anti-microbial Functions of Group 3 Innate Lymphoid Cells in Gut-Associated Lymphoid Tissues Are Regulated by G-Protein-Coupled Receptor 183 ', Cell Reports, vol. 23, no. 13, pp. 3750-3758 . https://doi.org/10.1016/j.celrep.2018.05.099
Cell reports
Chu, C, Moriyama, S, Li, Z, Zhou, L, Flamar, A L, Klose, C S N, Moeller, J B, Putzel, G G, Withers, D R, Sonnenberg, G F & Artis, D 2018, ' Anti-microbial Functions of Group 3 Innate Lymphoid Cells in Gut-Associated Lymphoid Tissues Are Regulated by G-Protein-Coupled Receptor 183 ', Cell Reports, vol. 23, no. 13, pp. 3750-3758 . https://doi.org/10.1016/j.celrep.2018.05.099
Cell reports
SUMMARY The intestinal tract is constantly exposed to various stimuli. Group 3 innate lymphoid cells (ILC3s) reside in lymphoid organs and in the intestinal tract and are required for immunity to enteric bacterial infection. However, the mechanisms t
Autor:
David Artis, Gregory G. Putzel, Lucille C. Rankin, Jesper B. Moeller, Christoph S.N. Klose, Laurel A. Monticelli, Saya Moriyama, Naomi Yudanin, Anne-Laure Flamar, Jonathan R. Brestoff, Hans Reimer Rodewald
Publikováno v:
Moriyama, S, Brestoff, J R, Flamar, A-L, Moeller, J B, Klose, C S N, Rankin, L C, Yudanin, N A, Monticelli, L A, Putzel, G G, Rodewald, H-R & Artis, D 2018, ' β 2-adrenergic receptor-mediated negative regulation of group 2 innate lymphoid cell responses ', Science, vol. 359, no. 6379, pp. 1056-1061 . https://doi.org/10.1126/science.aan4829
An off switch for helminth immunity Group 2 innate lymphoid cells (ILC2s) are involved in responses to helminths, viruses, and allergens. Moriyama et al. found that ILC2s interact with the nervous system to modulate helminth immunity. ILC2s from the
Autor:
Yannick d’Hargues, Jonas F. Hummel, Christoph S.N. Klose, Lena Faller, Yakup Tanriver, Karolina Ebert
Publikováno v:
Mucosal Immunology. 11:333-344
The intestine is a major immune organ with several specialized lymphoid structures and immune cells. Among these are thymus-derived natural intraepithelial lymphocytes (IELs) that lack expression of the classical co-receptors CD4 or CD8αβ (double n