Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christoph S. Janssen"'
Autor:
Marie-Adèle Rajandream, Mandy Sanders, Mark Simmonds, Danielle Walker, S. Sanders, Tobias Mourier, Celine Carret, Al Ivens, Thomas M. Keane, Jaina Mistry, Martin Aslett, Sharon Moule, Douglas Ormond, Tobias Sargeant, Alan W. Thomas, Inna Cherevach, Brian White, Clemens H. M. Kocken, Mary R. Galinski, S. Balasubrammaniam, R. Squares, Arnab Pain, Neil Hall, Alan F. Cowman, Andrew Berry, Stacey A. Lapp, Scott Thurston, Michael A. Quail, Karsten M. Borgwardt, Tim Carver, Nicholas S. Peters, Irmtraud M. Meyer, Frances Smith, Tracey Chillingworth, Taane G. Clark, Eduard Zuiderwijk, Matthew Berriman, Adrian Tivey, Matthias Marti, Chris I. Newbold, C. M. R. Turner, D. Harper, Natasha Larke, Christoph S. Janssen, Bart Barrell, Heidi Hauser, Erica M. Pasini, Carol Churcher, Karen Brooks, Ulrike Böhme, Andrew P. Jackson, Karen Mungall, Robert D. Finn, David Harris
Publikováno v:
Nature, 455
Plasmodium knowlesi is an intracellular malaria parasite whose natural vertebrate host is Macaca fascicularis (the ‘kra’ monkey); however, it is now increasingly recognized as a significant cause of human malaria, particularly in southeast Asia1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024c5eeb1be78d11c86df3f6b1611890
https://ora.ox.ac.uk/objects/uuid:d033391f-dc38-479c-9686-227efaed704c
https://ora.ox.ac.uk/objects/uuid:d033391f-dc38-479c-9686-227efaed704c
Publikováno v:
Proceedings of the Royal Society of London. Series B: Biological Sciences. 269:431-436
A major mechanism whereby malaria parasites evade the host immune response to give chronic infections in patients' blood for months, or even years, is antigenic variation. In order to generate variant antigens, parasites require large multigene famil
Autor:
Christoph S. Janssen, Michael P. Barrett, R. Stephen Phillips, Daniel Lawson, Michael A. Quail, Sharen Bowman, C. Michael R. Turner, David Harris
Publikováno v:
Molecular and Biochemical Parasitology. 113:251-260
The first genome survey sequencing of the rodent malaria parasite Plasmodium chabaudi is presented here. In 766 sequences, 131 putative gene sequences have been identified by sequence similarity database searches. Further, 7 potential gene families,
Publikováno v:
British Journal of Cancer
An activating mutation in exon 15 of the BRAF gene is present in a high proportion of cutaneous pigmented lesions. Until recently this mutation had however only been identified in one case of posterior uveal melanoma. Despite this apparent lack of th
Publikováno v:
Investigative ophthalmologyvisual science. 48(11)
PURPOSE. An activating mutation in exon 15 of the BRAF gene has been found in a high proportion of cutaneous pigmented lesions, but only in one case of uveal melanoma. Iris melanoma is the least common uveal melanoma and displays a less aggressive cl
Autor:
Laurence Florens, Doug Ormond, C. Michael R. Turner, Fotis C. Kafatos, Jacqui Mendoza, Shelby L. Bidwell, Marie Adele Rajandream, Neil Hall, Barbara Harris, Christoph S. Janssen, Jane M. Carlton, Michael A. Quail, Arnab Pain, Marianna Karras, Andrew P. Waters, Keith D. James, Robert E. Sinden, Holly E. Trueman, Daniel J. Carucci, Carol Churcher, Georges K. Christophides, Taco W. A. Kooij, John R. Yates, Matthew Berriman, J. Dale Raine, David Harris, Chris J. Janse, Jon Doggett, Bart Barrell, Kim Rutherford
Publikováno v:
Science (New York, N.Y.). 307(5706)
Plasmodium berghei and Plasmodium chabaudi are widely used model malaria species. Comparison of their genomes, integrated with proteomic and microarray data, with the genomes of Plasmodium falciparum and Plasmodium yoelii revealed a conserved core of
Publikováno v:
Nucleic acids research. 32(19)
Functionally related homologues of known genes can be difficult to identify in divergent species. In this paper, we show how multi-character analysis can be used to elucidate the relationships among divergent members of gene superfamilies. We used pr