Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Christoph S Clemen"'
Autor:
Florian Stöckigt, Lars Eichhorn, Thomas Beiert, Vincent Knappe, Tobias Radecke, Martin Steinmetz, Georg Nickenig, Viktoriya Peeva, Alexei P Kudin, Wolfram S Kunz, Carolin Berwanger, Lisa Kamm, Dorothea Schultheis, Ursula Schlötzer-Schrehardt, Christoph S Clemen, Rolf Schröder, Jan W Schrickel
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0228913 (2020)
BACKGROUND:Mutations in the human desmin gene (DES) cause autosomal-dominant and -recessive cardiomyopathies, leading to heart failure, arrhythmias, and AV blocks. We analyzed the effects of vascular pressure overload in a patient-mimicking p.R349P d
Externí odkaz:
https://doaj.org/article/9b3c7dcd411b41b8b55eb9e9f2bd2763
Autor:
Khalid Arhzaouy, Karl-Heinz Strucksberg, Sze Man Tung, Karthikeyan Tangavelou, Maria Stumpf, Jan Faix, Rolf Schröder, Christoph S Clemen, Ludwig Eichinger
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199548 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0046879.].
Externí odkaz:
https://doaj.org/article/e13e0b72d46a47fa983bf7ae37537566
Autor:
Linh Hai Vu, Tsuyoshi Araki, Jianbo Na, Christoph S Clemen, Jeffrey G Williams, Ludwig Eichinger
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90025 (2014)
Cellular adaptation to changes in environmental osmolarity is crucial for cell survival. In Dictyostelium, STATc is a key regulator of the transcriptional response to hyperosmotic stress. Its phosphorylation and consequent activation is controlled by
Externí odkaz:
https://doaj.org/article/c4219b28331e49c1b737e0caecd552fd
Autor:
Carolin Berwanger, Dominic Terres, Dominik Pesta, Britta Eggers, Katrin Marcus, Ilka Wittig, Rudolf J. Wiesner, Rolf Schröder, Christoph S. Clemen
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151399- (2024)
Desmin gene mutations cause myopathies and cardiomyopathies. Our previously characterised R349P desminopathy mice, which carry the ortholog of the common human desmin mutation R350P, showed marked alterations in mitochondrial morphology and function
Externí odkaz:
https://doaj.org/article/322edd1d0b5e42938e98a96645053b1d
Autor:
Khalid Arhzaouy, Karl-Heinz Strucksberg, Sze Man Tung, Karthikeyan Tangavelou, Maria Stumpf, Jan Faix, Rolf Schröder, Christoph S Clemen, Ludwig Eichinger
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46879 (2012)
Heterozygous mutations in the human VCP (p97) gene cause autosomal-dominant IBMPFD (inclusion body myopathy with early onset Paget's disease of bone and frontotemporal dementia), ALS14 (amyotrophic lateral sclerosis with or without frontotemporal dem
Externí odkaz:
https://doaj.org/article/00e2734f67aa4a1e9cd1d84adfd4350e
Autor:
Rakesh Ganji, Joao A. Paulo, Yuecheng Xi, Ian Kline, Jiang Zhu, Christoph S. Clemen, Conrad C. Weihl, John G. Purdy, Steve P. Gygi, Malavika Raman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Inter-organellar contacts are hubs for several critical cellular processes, such as lipid synthesis. Here Ganji et al. show that the p97-UBXD8 complex modulates contacts by regulating membrane lipid composition and saturation.
Externí odkaz:
https://doaj.org/article/ec8b699c1b3c422ea6b756578b81cfd6
Autor:
Janet Mansour, Carolin Berwanger, Marcel Jung, Ludwig Eichinger, Ben Fabry, Christoph S. Clemen
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 2, Pp 151330- (2023)
To study processes related to weightlessness in ground-based cell biological research, a theoretically assumed microgravity environment is typically simulated using a clinostat – a small laboratory device that rotates cell culture vessels with the
Externí odkaz:
https://doaj.org/article/cda03b84f76c49e5aa384e12e483ccb0
Autor:
Qiuhong Xiong, Rong Feng, Sarah Fischer, Malte Karow, Maria Stumpf, Susanne Meßling, Leonie Nitz, Stefan Müller, Christoph S. Clemen, Ning Song, Ping Li, Changxin Wu, Ludwig Eichinger
Publikováno v:
Cells, Vol 12, Iss 11, p 1514 (2023)
Autophagy and the ubiquitin proteasome system are the two major processes for the clearance and recycling of proteins and organelles in eukaryotic cells. Evidence is accumulating that there is extensive crosstalk between the two pathways, but the und
Externí odkaz:
https://doaj.org/article/b91cdcd1cd9e420688ca1b8b2fca1838
Autor:
Britta Eggers, Karin Schork, Michael Turewicz, Katalin Barkovits, Martin Eisenacher, Rolf Schröder, Christoph S. Clemen, Katrin Marcus
Publikováno v:
Proteomes, Vol 9, Iss 2, p 28 (2021)
Skeletal muscle is a heterogeneous tissue consisting of blood vessels, connective tissue, and muscle fibers. The last are highly adaptive and can change their molecular composition depending on external and internal factors, such as exercise, age, an
Externí odkaz:
https://doaj.org/article/fe582d8bc4c1418d869b60e2510dd194
Autor:
Barbara Elsnicova, Daniela Hornikova, Veronika Tibenska, David Kolar, Tereza Tlapakova, Benjamin Schmid, Markus Mallek, Britta Eggers, Ursula Schlötzer-Schrehardt, Viktoriya Peeva, Carolin Berwanger, Bettina Eberhard, Hacer Durmuş, Dorothea Schultheis, Christian Holtzhausen, Karin Schork, Katrin Marcus, Jens Jordan, Thomas Lücke, Peter F. M. van der Ven, Rolf Schröder, Christoph S. Clemen, Jitka M. Zurmanova
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 12020
International Journal of Molecular Sciences [online] 23(19), nestránkováno. (2022)
International Journal of Molecular Sciences [online] 23(19), nestránkováno. (2022)
Desmin mutations cause familial and sporadic cardiomyopathies. In addition to perturbing the contractile apparatus, both desmin deficiency and mutated desmin negatively impact mitochondria. Impaired myocardial metabolism secondary to mitochondrial de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19ad60d1d81ab8fb4764ce8cf6e21b7
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/20790
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/20790
