Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Christoph Rumancev"'
Autor:
Kai Hilpert, Christoph Rumancev, Jurnorain Gani, Dominic W. P. Collis, Paula Matilde Lopez-Perez, Vasil M. Garamus, Ralf Mikut, Axel Rosenhahn
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The opportunistic yeast Candida albicans is the most common cause of candidiasis. With only four classes of antifungal drugs on the market, resistance is becoming a problem in the treatment of fungal infections, especially in immunocompromised patien
Externí odkaz:
https://doaj.org/article/28cfbb9bce624ba28163d372edca6fb1
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Antimicrobial resistance is a worldwide threat to modern health care. Low-profit margin and high risk of cross-resistance resulted in a loss of interest in big pharma, contributing to the increasing threat. Strategies to address the problem are start
Externí odkaz:
https://doaj.org/article/2ce2b3ff08474cdfab010221c8d5ee16
Autor:
Kai Hilpert, Jurnorain Gani, Christoph Rumancev, Nathan Simpson, Paula Matilde Lopez-Perez, Vasil M. Garamus, Andreas Robert von Gundlach, Petar Markov, Marco Scocchi, Ralf Mikut, Axel Rosenhahn
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Antimicrobial peptides (AMPs) are a promising class of compounds being developed against multi-drug resistant bacteria. Hybridization has been reported to increase antimicrobial activity. Here, two proline-rich peptides (consP1: VRKPPYLPRPRPRPL-CONH2
Externí odkaz:
https://doaj.org/article/3eea9ed054df43e8ab7a3bde63e39013
Autor:
Andreas von Gundlach, Martin P. Ashby, Jurnorain Gani, Paula Matilde Lopez-Perez, Alan Roy Cookson, Sharon Ann Huws, Christoph Rumancev, Vasil M. Garamus, Ralf Mikut, Axel Rosenhahn, Kai Hilpert
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Two highly active short broad-spectrum AMPs (14D and 69D) with unknown mode of action have been investigated in regards to their effect against the Gram-negative bacteria Escherichia coli and the Gram-positive bacteria methicillin-resistant Staphyloc
Externí odkaz:
https://doaj.org/article/fd889a1536a1414588891f2c989b26a5
Autor:
Kai Hilpert, Christoph Rumancev, Jurnorain Gani, Dominic W. P. Collis, Paula Matilde Lopez-Perez, Vasil M. Garamus, Ralf Mikut, Axel Rosenhahn
The opportunistic yeastCandida albicansis the most common cause of candidiasis. With only four classes of antifungal drugs on the market, resistance is becoming a problem in the treatment of fungal infections, especially in immunocompromised patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b12266544e86fcca931eec7ec486dcd1
https://doi.org/10.1101/2023.05.12.540542
https://doi.org/10.1101/2023.05.12.540542
Autor:
Andreas Gräfenstein, Christoph Rumancev, Roland Pollak, Benjamin Hämisch, Vanessa Galbierz, Walter H. Schroeder, Jan Garrevoet, Gerald Falkenberg, Tobias Vöpel, Klaus Huber, Simon Ebbinghaus, Axel Rosenhahn
Publikováno v:
ChemistryOpen 11(4), e202200024 (2022). doi:10.1002/open.202200024
ChemistryOpen 11(4), e202200024 (2022). doi:10.1002/open.202200024
Protein aggregation is a hallmark of several severe neurodegenerative disorders such as Huntington's, Parkinson's, or Alzheimer's disease. Metal ions play a profound role in prot
Protein aggregation is a hallmark of several severe neurodegenerative disorders such as Huntington's, Parkinson's, or Alzheimer's disease. Metal ions play a profound role in prot
Autor:
Axel Rosenhahn, Junjie Li, Holger V. Lutze, Oliver J. Schmitz, Christoph Rumancev, Torsten C. Schmidt
Publikováno v:
Analytical and Bioanalytical Chemistry
A GCxGC-MS system was employed with a non-polar × mid-polar column set for the metabolic non-target analysis of Cobetia marina, the model bacteria for marine biofouling. C. marina was treated with ozone to investigate the intracellular metabolic sta
Autor:
Nathan Simpson, Marco Scocchi, Petar Markov, Christoph Rumancev, Jurnorain Gani, Ralf Mikut, Kai Hilpert, Vasil M. Garamus, Axel Rosenhahn, Paula Matilde Lopez-Perez, Andreas von Gundlach
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in pharmacology 12, 769739 (2021). doi:10.3389/fphar.2021.769739
Hilpert, K.; Gani, J.; Rumancev, C.; Simpson, N.; Lopez-Perez, P.; Garamus, V.; von Gundlach, A.; Markov, P.; Scocchi, M.; Mikut, R.; Rosenhahn, A.: Rational Designed Hybrid Peptides Show up to a 6-Fold Increase in Antimicrobial Activity and Demonstrate Different Ultrastructural Changes as the Parental Peptides Measured by BioSAXS. In: Frontiers In Pharmacology . Vol. 12 (2021) 769739. (DOI: /10.3389/fphar.2021.769739)
Frontiers in Pharmacology
Frontiers in pharmacology 12, 769739 (2021). doi:10.3389/fphar.2021.769739
Hilpert, K.; Gani, J.; Rumancev, C.; Simpson, N.; Lopez-Perez, P.; Garamus, V.; von Gundlach, A.; Markov, P.; Scocchi, M.; Mikut, R.; Rosenhahn, A.: Rational Designed Hybrid Peptides Show up to a 6-Fold Increase in Antimicrobial Activity and Demonstrate Different Ultrastructural Changes as the Parental Peptides Measured by BioSAXS. In: Frontiers In Pharmacology . Vol. 12 (2021) 769739. (DOI: /10.3389/fphar.2021.769739)
Frontiers in pharmacology 12, 769739 (2021). doi:10.3389/fphar.2021.769739
Antimicrobial peptides (AMPs) are a promising class of compounds being developed against multi-drug resistant bacteria. Hybridization has been reported to increase antimi
Antimicrobial peptides (AMPs) are a promising class of compounds being developed against multi-drug resistant bacteria. Hybridization has been reported to increase antimi
Autor:
Simon Ebbinghaus, Andreas von Gundlach, Susan Stuhr, Christoph Rumancev, Markus Osterhoff, Tobias Vöpel, Tobias Senkbeil, Vasil M. Garamus, Michael Sprung, Axel Rosenhahn
Publikováno v:
Rumancev, C.; Vöpel, T.; Stuhr, S.; von Gundlach, A.; Senkbeil, T.; Osterhoff, M.; Sprung, M.; Garamus, V.; Ebbinghaus, S.; Rosenhahn, A.: In Cellulo Analysis of Huntingtin Inclusion Bodies by Cryogenic Nanoprobe SAXS. In: ChemSystemsChem. Vol. 3 (2021) 3, e2000050. (DOI: /10.1002/syst.202000050)
ChemSystemsChem 3(3), e2000050 (2021). doi:10.1002/syst.202000050
ChemSystemsChem 3(3), e2000050 (2021). doi:10.1002/syst.202000050
ChemSystemsChem 3(3), e2000050 (2021). doi:10.1002/syst.202000050
Huntington's disease (HD) is one of nine neurodegenerative disorders associated with an extension of polyglutamine (polyQ) in proteins. In HD, the polyQ tract in the huntingtin pr
Huntington's disease (HD) is one of nine neurodegenerative disorders associated with an extension of polyglutamine (polyQ) in proteins. In HD, the polyQ tract in the huntingtin pr
Autor:
Björn De Samber, Simon Ebbinghaus, Christoph Rumancev, Andreas von Gundlach, Laszlo Vincze, Tobias Senkbeil, Tobias Vöpel, Susan Stuhr, Gerald Falkenberg, Walter Schroeder, Jan Garrevoet, Axel Rosenhahn
Publikováno v:
Biointerphases
BIOINTERPHASES
Biointerphases 16(1), 011004 (1-8) (2021). doi:10.1116/6.0000593
BIOINTERPHASES
Biointerphases 16(1), 011004 (1-8) (2021). doi:10.1116/6.0000593
Biointerphases 16(1), 011004 (1-8) (2021). doi:10.1116/6.0000593
X-ray fluorescence analysis enables the study of trace element distributions in biological specimens. When this analysis is done under cryogenic conditions, cells are cryofixed as
X-ray fluorescence analysis enables the study of trace element distributions in biological specimens. When this analysis is done under cryogenic conditions, cells are cryofixed as