Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Christoph Rösli"'
Autor:
Christoph Weigel, Marlon R. Veldwijk, Christopher C. Oakes, Petra Seibold, Alla Slynko, David B. Liesenfeld, Mariona Rabionet, Sabrina A. Hanke, Frederik Wenz, Elena Sperk, Axel Benner, Christoph Rösli, Roger Sandhoff, Yassen Assenov, Christoph Plass, Carsten Herskind, Jenny Chang-Claude, Peter Schmezer, Odilia Popanda
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Radiotherapy can induce fibrosis in cancer patients, limiting its use in clinical settings. Here, the authors identify a differentially methylated enhancer of the lipid kinase DGKA in fibroblasts from breast cancer patients developing fibrosis after
Externí odkaz:
https://doaj.org/article/8d2cbcdc585d437387a5d8eedf91802c
Publikováno v:
Journal of Proteomics. 141:57-66
A promising approach for the development of novel therapeutics with fewer side effects in healthy tissues is the targeted delivery of bioactive molecules directly to the site of disease. Thus, one prerequisite is the identification of a robust, disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::220b78a97ad3610a2baa21f9af049efd
https://doi.org/10.1016/j.jprot.2016.04.014
https://doi.org/10.1016/j.jprot.2016.04.014
Autor:
Jenny Chang-Claude, Christopher C. Oakes, Yassen Assenov, Marlon R. Veldwijk, David B. Liesenfeld, Christoph Rösli, Alla Slynko, Roger Sandhoff, Sabrina Hanke, Christoph Weigel, Petra Seibold, Mariona Rabionet, Elena Sperk, Axel Benner, Peter Schmezer, Odilia Popanda, Carsten Herskind, Frederik Wenz, Christoph Plass
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communications
Nature Communications
Radiotherapy is a fundamental part of cancer treatment but its use is limited by the onset of late adverse effects in the normal tissue, especially radiation-induced fibrosis. Since the molecular causes for fibrosis are largely unknown, we analyse if
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0c57aa34b04827e0b7f534875df946
https://doaj.org/article/8d2cbcdc585d437387a5d8eedf91802c
https://doaj.org/article/8d2cbcdc585d437387a5d8eedf91802c
Publikováno v:
PROTEOMICS. 14:2427-2431
Mass spectrometers equipped with matrix-assisted laser desorption/ionization (MALDI-MS) require frequent multipoint calibration to obtain good mass accuracy over a wide mass range and across large numbers of samples. In this study, we introduce a new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9032675d95ad574e2261ecfe195523eb
https://doi.org/10.1002/pmic.201400199
https://doi.org/10.1002/pmic.201400199
Autor:
Markus W. Büchler, Albrecht Stenzinger, Thilo Hackert, Bernd Klaus, Nathalia Giese, Octavio Espinosa, Jan Engelhardt, Elisa Espinet, Marcus Bahra, Matthias Schlesner, Michael Kulke, Wiebke Nadler, Christian Eisen, Vanessa Vogel, Elisa M. Noll, Annette Kopp-Schneider, Bruno Valentin Sinn, Jens Werner, Andreas Trumpp, Franziska M. Zickgraf, Corinna Klein, Xiaoqi Jiang, Christoph Rösli, Wilko Weichert, Oliver Strobel, Peter Neuhaus, Martin R. Sprick, Christian Lutz, Roland Eils, Alexander Muckenhuber
Publikováno v:
Nature medicine
Although subtypes of pancreatic ductal adenocarcinoma (PDAC) have been described, this malignancy is clinically still treated as a single disease. Here we present patient-derived models representing the full spectrum of previously identified quasi-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1859f5860007ff096815e451d338eb44
https://pubmed.ncbi.nlm.nih.gov/30581769
https://pubmed.ncbi.nlm.nih.gov/30581769
Autor:
Marleen Büchler, Paul Kaschutnig, Roshana Thambyrajah, Wiebke Nadler, Sabrina Hanke, Stella Pfaffenholz, Julius Gräsel, Jakob Kremer, Milena Block, Irem Bayindir-Buchhalter, David Hills, Andreas Trumpp, Marc Thier, Loïc Maillard, Nico Lachmann, Mania Ackermann, Thomas Moritz, Christoph Rösli, Alexander Medvinski, Michèle Souyri, Georges Lacaud, Michael Milsom
Publikováno v:
Experimental Hematology. 53:S121
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b342142ef336326e608384032fcb5241
https://doi.org/10.1016/j.exphem.2017.06.302
https://doi.org/10.1016/j.exphem.2017.06.302
Autor:
Christian Eisen, Jan Engelhardt, Elisa M. Noll, Alexander Muckenhuber, Annette Kopp-Schneider, Andreas Trumpp, Jens Werner, Oliver Strobel, Elisa Espinet, Michael Kulke, Bernd Klaus, Wiebke Nadler, Martin R. Sprick, Vanessa Vogel, Christian Lutz, Roland Eils, Xiaoqi Jiang, Christoph Rösli, Wilko Weichert, Peter Neuhaus, Matthias Schlesner, Marcus Bahra, Thilo Hackert, Bruno Valentin Sinn, Franziska M. Zickgraf, Corinna Klein, Nathalia A. Giese, Markus W. Büchler, Octavio Espinosa, Albrecht Stenzinger
Publikováno v:
Cancer Research. 76:B77-B77
Pancreatic ductal adenocarcinoma (PDAC) is a very aggressive disease with poor prognosis. Treatment with gemcitabine, the FOLFIRINOX scheme or nab-paclitaxel offer only a modest increase in overall survival. For a number of other carcinomas, tumor su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da5a3b2c56ce8dfb8e6cce6b9b9a06e4
https://doi.org/10.1158/1538-7445.panca16-b77
https://doi.org/10.1158/1538-7445.panca16-b77
Autor:
Irem Bayindir-Buchhalter, Milena Block, David Hills, Christoph Rösli, Ruzhica Bogeska, Andreas Trumpp, Alexander Medvinsky, Paul Kaschutnig, Michael D. Milsom, Marc Thier, Sabrina Hanke, Stella Paffenholz, Wiebke Nadler
Publikováno v:
Experimental Hematology. 44:S84
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89cc9b29bc8d875f226425f1e52ad9db
https://doi.org/10.1016/j.exphem.2016.06.169
https://doi.org/10.1016/j.exphem.2016.06.169
Autor:
Elisa M. Noll, Christian Eisen, Albrecht Stenzinger, Elisa Espinet, Alexander Muckenhuber, Corinna Klein, Vanessa Vogel, Bernd Klaus, Wiebke Nadler, Christoph Rösli, Christian Lutz, Michael Kulke, Jan Engelhardt, Franziska Zickgraf, Octavio Espinosa, Matthias Schlesner, Xiaoqi Jiang, Annette Kopp-Schneider, Peter Neuhaus, Marcus Bahra, Bruno Sinn, Roland Eils, Nathalia Giese, Thilo Hackert, Oliver Strobel, Jens Werner, Markus W. Büchler, Wilko Weichert, Andreas Trumpp, Martin R. Sprick
Publikováno v:
Cancer Research. 76:LB-120
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease with poor prognosis. Treatment with gemcitabine, the FOLFIRINOX scheme or nab-paclitaxel offer only a modest increase in overall survival. For a number of other carcinomas, tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90bd5eeba1d1103f01e8a9da04f8c672
https://doi.org/10.1158/1538-7445.am2016-lb-120
https://doi.org/10.1158/1538-7445.am2016-lb-120
Autor:
Anna Barbara Küntzel, Vincent S. Tchang, Annette Oxenius, Burkhard Ludewig, Nicole Joller, Elke Scandella, Christoph Rösli, Roman Spörri, Stefan S. Weber, Hubert Hilbi
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 189(2)
Abs confer protection from secondary infection with Legionella pneumophila, the causative agent of a severe form of pneumonia known as Legionnaires’ disease. In this study, we demonstrate that Ab-mediated protection is effective across L. pneumophi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6529f952f5d8bc260babef8817b4ff
https://pubmed.ncbi.nlm.nih.gov/22696443
https://pubmed.ncbi.nlm.nih.gov/22696443