Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Christoph Priesner"'
1
Akademický článek
Automated manufacturing and characterization of clinical grade autologous CD20 CAR T cells for the treatment of patients with stage III/IV melanoma
Autor: Krasimira Aleksandrova, Jana Leise, Christoph Priesner, Murat Aktas, Michael Apel, Mario Assenmacher, Iris Bürger, Anne Richter, Pia Altefrohne, Christine Schubert, Astrid Holzinger, Markus Barden, Valerie Bezler, Michael von Bergwelt-Baildon, Peter Borchmann, Lilia Goudeva, Wolfgang Glienke, Lubomir Arseniev, Ruth Esser, Hinrich Abken, Ulrike Koehl
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
IntroductionPoint-of-care (POC) manufacturing of chimeric antigen receptor (CAR) modified T cell has expanded rapidly over the last decade. In addition to the use of CD19 CAR T cells for hematological diseases, there is a growing interest in targetin
Externí odkaz: https://doaj.org/article/f6589c518506495e91a9217ebb7da6b4
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2
Akademický článek
Comparative analysis of clinical-scale IFN-gamma positive T-cell enrichment using partially and fully integrated platforms
Autor: Christoph Priesner, Ruth Esser, Sabine Tischer, Michael Marburger, Krasimira Aleksandrova, Britta Maecker-Kolhoff, Hans-Gert Heuft, Lilia Goudeva, Rainer Blasczyk, Lubomir Arseniev, Ulrike Koehl, Britta Eiz-Vesper, Stephan Kloess
Publikováno v: Frontiers in Immunology, Vol 7 (2016)
Background and aims. The infusion of enriched CMV-specific donor T-cells appears to be a suitable alternative for the treatment of drug resistant CMV reactivation or de novo infection after both solid organ and hematopoietic stem cell transplantation
Externí odkaz: https://doaj.org/article/d568e57addaa488db7f99d883dc8d874
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3
Advanced Therapy Medicinal Products and the Changing Role of Academia
Autor: Christoph, Priesner, Martin, Hildebrandt
Publikováno v: Transfus Med Hemother
Academic institutions coin the ATMP landscape but do not possess an industry-like capacity to vigorously pursue the full developmental pathway to marketing authorization. At the same time, industry has fostered clinical trials with ATMPs, brought the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ff4a3e9cdfb81b0bfd633607030994
https://doi.org/10.1159/000524392
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4
Erfolgreiche Zelltherapie mit virusspezifischen T-Zellen vom HLA-teilkompatiblen Drittspender bei disseminierter Adenovirus-Infektion früh nach allogener Stammzelltransplantation
Autor: Kinan Kafa, Britta Eiz-Vesper, Rainer Blasczyk, Sabine Tischer, Britta Maecker-Kolhoff, Christoph Priesner, Jan-Henning Klusmann, Hans-Gert Heuft
Publikováno v: TumorDiagnostik & Therapie. 40:50-55
ZusammenfassungAdenovirus-Infektionen (AdV-Infektionen) nach pädiatrischer hämatopoetischer Stammzelltransplantation sind häufig und treten in 10 – 20 % aller allogenen Transplantationen auf (bis 30 % der T-Zell-depletierten Transplantationen).
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef754f010eb07de87d347517b7dc104
https://doi.org/10.1055/a-0829-2886
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5
Transfer of Hexon‐ and Penton‐selected adenovirus‐specific T cells for refractory adenovirus infection after haploidentical stem cell transplantation
Autor: Hans-Gert Heuft, Britta Lamottke, Rainer Blasczyk, Britta Eiz-Vesper, Christoph Priesner, Albert Heim, Sabine Tischer-Zimmermann, Karl-Walter Sykora, Britta Maecker-Kolhoff, Martin Sauer, Rebecca E Schultze-Florey
Publikováno v: Transplant Infectious Disease. 22
Adenovirus (HAdV) infections confer a high risk of morbidity and mortality for immunocompromised patients after stem cell transplantation (SCT). Treatment with standard antiviral drugs is of limited efficacy and associated with a high rate of adverse
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9df3be7b3312db53b086e590e2589537
https://doi.org/10.1111/tid.13201
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6
Automated Enrichment, Transduction, and Expansion of Clinical-Scale CD62L+ T Cells for Manufacturing of Gene Therapy Medicinal Products
Autor: Lilia Goudeva, Michael Marburger, Lubomir Arseniev, Wolfgang Glienke, Jana Leise, Krasimira Aleksandrova, Ruth Esser, Andrew Kaiser, Christoph Priesner, Nadine Mockel-Tenbrinck, Andrea Quaiser, Katharina Drechsel, Ulrike Koehl
Publikováno v: Human Gene Therapy
Multiple clinical studies have demonstrated that adaptive immunotherapy using redirected T cells against advanced cancer has led to promising results with improved patient survival. The continuously increasing interest in those advanced gene therapy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db25f2a2433949cb157364fee0b6828
https://doi.org/10.1089/hum.2016.091
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Functionality and Cell Senescence of CD4/ CD8-Selected CD20 CAR T Cells Manufactured Using the Automated CliniMACS Prodigy® Platform
Autor: Lilia Goudeva, Fanni Kubaink, Jana Leise, Wolfgang Glienke, Andrew Kaiser, Hinrich Abken, Mike Essl, Ruth Esser, Andreas Hombach, Marion Jurk, Lubomir Arseniev, Murat Aktas, Krasimira Aleksandrova, Ulrike Köhl, Georg Rauser, Iris Bürger, Christoph Priesner, Anette Melk
Publikováno v: Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie. 46(1)
Clinical studies using autologous CAR T cells have achieved spectacular remissions in refractory CD19+ B cell leukaemia, however some of the patient treatments with CAR T cells failed. Beside the heterogeneity of leukaemia, the distribution and senes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfba8cfc82b49cd300692a8b0c6da3b6
https://pubmed.ncbi.nlm.nih.gov/31244581
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8
Comparative analysis of clinical-scale IFN-gamma positive T-cell enrichment using partially and fully integrated platforms
Autor: Lubomir Arseniev, Britta Eiz-Vesper, Lilia Goudeva, Hans-Gert Heuft, Sabine Tischer, Rainer Blasczyk, Ulrike Köhl, Stephan Klöß, Krasimira Aleksandrova, Ruth Esser, Britta Maecker-Kolhoff, Christoph Priesner, Michael Marburger
Publikováno v: Frontiers in Immunology, Vol 7 (2016)
Frontiers in Immunology
Background and aims. The infusion of enriched CMV-specific donor T-cells appears to be a suitable alternative for the treatment of drug resistant CMV reactivation or de novo infection after both solid organ and hematopoietic stem cell transplantation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c92c9ed2ba529a31bf1d107fdea7a0
http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00393/full
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10
Rapid generation of clinical-grade antiviral T cells: selection of suitable T-cell donors and GMP-compliant manufacturing of antiviral T cells
Autor: Marc Barthold, Sabine Tischer, Lubomir Arseniev, Lilia Goudeva, Britta Maecker-Kolhoff, Rainer Blasczyk, Krasimira Aleksandrova, Wolfgang Mende, Britta Eiz-Vesper, Stephan Kloeß, Ulrike Koehl, Christoph Priesner, Hans-Gert Heuft
Publikováno v: Journal of Translational Medicine
Background The adoptive transfer of allogeneic antiviral T lymphocytes derived from seropositive donors can safely and effectively reduce or prevent the clinical manifestation of viral infections or reactivations in immunocompromised recipients after
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a81fec9402a812b14f7b50451330ca1
http://europepmc.org/articles/PMC4335407
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