Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christoph Plüss"'
Publikováno v:
Biochemical and Biophysical Research Communications. 251:802-805
GTP cyclohydrolase I is the rate-limiting enzyme in the de novo synthesis pathway of tetrahydrobiopterin which is an essential cofactor for all NO synthase isoforms. The expression of GTP cyclohydrolase I is regulated on a transcriptional level by a
Publikováno v:
The Journal of Immunology. 160:4961-4969
Expression of the inducible nitric oxide synthase (iNOS) gene in rat mesangial cells is differentially triggered by IL-1β and cAMP predominantly at the transcriptional level. The 5′-flanking region of the rat iNOS gene contains several binding sit
Autor:
Christoph Plüss, Ariel Lustig, Ernst R. Werner, Richard A. Kammerer, Andreas Engel, Ueli Aebi, Josef Pfeilschifter, Helmut Wachter, Urs Christen, Bettina Wolpensinger, Michel O. Steinmetz
Publikováno v:
Journal of Molecular Biology. 279:189-199
Recombinant rat liver GTP cyclohydrolase I has been prepared by heterologous gene expression in Escherichia coli and characterized by biochemical and biophysical methods. Correlation averaged electron micrograph images of preferentially oriented enzy
Publikováno v:
British Journal of Pharmacology. 122:534-538
1 Endogenous synthesis of tetrahydrobiopterin (BH4) is an essential requirement for cytokine-stimulated nitric oxide (NO) synthesis in rat mesangial cells. GTP cyclohydrolase I, the rate-limiting enzyme in BH4 synthesis, is expressed in renal mesangi
Publikováno v:
Pteridines, Vol 6, Iss 3, Pp 129-131 (1995)
Publikováno v:
The Biochemical journal. 318
Endogenous synthesis of tetrahydrobiopterin (BH4) is an important requirement for cytokine-stimulated nitric oxide (NO) production in mesangial cells. We have shown that inducible NO synthase is expressed in mesangial cells in response to two princip
Autor:
Dorothea Nitsch, Dieter Kunz, Christoph Plüss, Heiko Mühl, W. Eberhardt, Josef Pfeilschifter, Gaby Walker, Richard Hummel
Publikováno v:
Cell biology international. 20(1)
In recent years, NO, a gas previously considered a potentially toxic chemical, has become established as a diffusible universal messenger mediating cell-cell communication throughout the body. In mammals, NO is a recognized mediator of blood vessel r