Zobrazeno 1 - 10
of 434
pro vyhledávání: '"Christoph Peter"'
Autor:
Laura Schmitt, Julia Hoppe, Pablo Cea-Medina, Peter-Martin Bruch, Karina S. Krings, Ilka Lechtenberg, Daniel Drießen, Christoph Peter, Sanil Bhatia, Sascha Dietrich, Björn Stork, Gerhard Fritz, Holger Gohlke, Thomas J. J. Müller, Sebastian Wesselborg
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract A key feature of cancer is the disruption of cell cycle regulation, which is characterized by the selective and abnormal activation of cyclin-dependent kinases (CDKs). Consequently, targeting CDKs via meriolins represents an attractive thera
Externí odkaz:
https://doaj.org/article/63272546db6a4c5fbc60190ad36400b2
Autor:
Laura Schmitt, Ilka Lechtenberg, Daniel Drießen, Hector Flores-Romero, Margaretha A. Skowron, Marlena Sekeres, Julia Hoppe, Karina S. Krings, Tanya R. Llewellyn, Christoph Peter, Björn Stork, Nan Qin, Sanil Bhatia, Daniel Nettersheim, Gerhard Fritz, Ana J. García-Sáez, Thomas J. J. Müller, Sebastian Wesselborg
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Meriolin derivatives represent a new class of kinase inhibitors with a pronounced cytotoxic potential. Here, we investigated a newly synthesized meriolin derivative (termed meriolin 16) that displayed a strong apoptotic potential in Jurkat l
Externí odkaz:
https://doaj.org/article/bb0b5a2076ab4d3192f705aa5b86dbd2
Autor:
Christoph Peter, Martin Tajmar
Publikováno v:
IEEE Access, Vol 12, Pp 114618-114625 (2024)
A method for optimizing multiple responses in solenoids utilized in a magnetic nozzle assembly for an electric plasma thruster is presented. The primary goal is to minimize power usage while maintaining a sufficiently high magnetic flux density at th
Externí odkaz:
https://doaj.org/article/f1c3b7c364bf4943970f08a8c29f3b3a
Autor:
Silvia Schest, Claus Langer, Yuriko Stiegler, Bianca Karnuth, Jan Arends, Hugo Stiegler, Thomas Masetto, Christoph Peter, Matthias Grimmler
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundQuantification of the SARS-CoV-2-specific immune response by serological immunoassays is critical for the management of the COVID-19 pandemic. In particular, neutralizing antibody titers to the viral spike (S) protein have been proposed as
Externí odkaz:
https://doaj.org/article/1fc3eed9b5544c78995a5ed09e1512f6
Autor:
Lea Marie Esser, Katharina Schmitz, Frank Hillebrand, Steffen Erkelenz, Heiner Schaal, Björn Stork, Matthias Grimmler, Sebastian Wesselborg, Christoph Peter
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 2100-2109 (2023)
The spliceosome, responsible for all mature protein-coding transcripts of eukaryotic intron-containing genes, consists of small uridine-rich nuclear ribonucleoproteins (UsnRNPs). The assembly of UsnRNPs depends, on one hand, on the arginine methylati
Externí odkaz:
https://doaj.org/article/104567e091404490bf1af5bf1619f414
Autor:
Radovan Kopecek, Florian Buchholz, Valentin D. Mihailetchi, Joris Libal, Jan Lossen, Ning Chen, Haifeng Chu, Christoph Peter, Tudor Timofte, Andreas Halm, Yonggang Guo, Xiaoyong Qu, Xiang Wu, Jiaqing Gao, Peng Dong
Publikováno v:
Solar, Vol 3, Iss 1, Pp 1-14 (2022)
We present our own Interdigitated Back Contact (IBC) technology, which was developed at ISC Konstanz and implemented in mass production with and at SPIC Solar in Xining, China, with production efficiencies of over 24%. To our knowledge, this is the h
Externí odkaz:
https://doaj.org/article/81838d17bf6c4d04a1a46ed1d4967589
Autor:
Fabian Stuhldreier, Laura Schmitt, Thomas Lenz, Ilka Hinxlage, Marcel Zimmermann, Philipp Wollnitzke, Julian Schliehe-Diecks, Yang Liu, Paul Jäger, Stefanie Geyh, Nicole Teusch, Christoph Peter, Sanil Bhatia, Rainer Haas, Bodo Levkau, Andreas S. Reichert, Kai Stühler, Peter Proksch, Björn Stork, Sebastian Wesselborg
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-17 (2022)
Abstract Inhibition of the mitochondrial metabolism offers a promising therapeutic approach for the treatment of cancer. Here, we identify the mycotoxin viriditoxin (VDT), derived from the endophytic fungus Cladosporium cladosporioides, as an interes
Externí odkaz:
https://doaj.org/article/7e96c5faca6e4597a6d4c5bd9fe0a680
Autor:
Lea Marie Esser, Qiaoping Li, Maximilian Jüdt, Thilo Kähne, Björn Stork, Matthias Grimmler, Sebastian Wesselborg, Christoph Peter
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15552 (2023)
The survival motor neuron (SMN) complex is a multi-megadalton complex involved in post-transcriptional gene expression in eukaryotes via promotion of the biogenesis of uridine-rich small nuclear ribonucleoproteins (UsnRNPs). The functional center of
Externí odkaz:
https://doaj.org/article/c90c620011c14a0889a2803eecb9d243
Autor:
Jessica Brehm, Alexander Spaeth, Lars Dreßler, Thomas Masetto, Rainer Dannenberg, Christoph Peter, Matthias Grimmler
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundSince December 2019, SARS-CoV-2 has been keeping the world in suspense. Rapid tests, molecular diagnosis of acute infections, and vaccination campaigns with vaccines are building blocks of strategic pandemic control worldwide. For laborator
Externí odkaz:
https://doaj.org/article/4b0837eaf86a4f3d97aca945a49ba4b0
Autor:
Thomas Masetto, Kai Matzenbach, Thomas Reuschel, Sebastian-Alexander Tölke, Klaus Schneider, Lea Marie Esser, Marco Reinhart, Laura Bindila, Christoph Peter, Matthias Grimmler
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10963 (2023)
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. The fast and accurate diagnosis of sepsis by procalcitonin (PCT) has emerged as an essential tool in clinical medicine. Although in use in the clinica
Externí odkaz:
https://doaj.org/article/5e3c6f0a352e4fa5ba0d01cd23da91d4