Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Christoph Ogris"'
Autor:
Seddik Hammad, Christoph Ogris, Amnah Othman, Pia Erdoesi, Wolfgang Schmidt-Heck, Ina Biermayer, Barbara Helm, Yan Gao, Weronika Piorońska, Christian H. Holland, Lorenza A. D’Alessandro, Carolina de la Torre, Carsten Sticht, Sherin Al Aoua, Fabian J. Theis, Heike Bantel, Matthias P. Ebert, Ursula Klingmüller, Jan G. Hengstler, Steven Dooley, Nikola S. Mueller
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-13 (2023)
Abstract The human liver has a remarkable capacity to regenerate and thus compensate over decades for fibrosis caused by toxic chemicals, drugs, alcohol, or malnutrition. To date, no protective mechanisms have been identified that help the liver tole
Externí odkaz:
https://doaj.org/article/51b08471f4314fc5a23b5a9f8fd9aea5
Autor:
Michal Pardo, Svenja Offer, Elena Hartner, Sebastiano Di Bucchianico, Christoph Bisig, Stefanie Bauer, Jana Pantzke, Elias J. Zimmermann, Xin Cao, Stephanie Binder, Evelyn Kuhn, Anja Huber, Seongho Jeong, Uwe Käfer, Eric Schneider, Arunas Mesceriakovas, Jan Bendl, Ramona Brejcha, Angela Buchholz, Daniela Gat, Thorsten Hohaus, Narges Rastak, Erwin Karg, Gert Jakobi, Markus Kalberer, Tamara Kanashova, Yue Hu, Christoph Ogris, Annalisa Marsico, Fabian Theis, Tali Shalit, Thomas Gröger, Christopher P. Rüger, Sebastian Oeder, Jürgen Orasche, Andreas Paul, Till Ziehm, Zhi-Hui Zhang, Thomas Adam, Olli Sippula, Martin Sklorz, Jürgen Schnelle-Kreis, Hendryk Czech, Astrid Kiendler-Scharr, Ralf Zimmermann, Yinon Rudich
Publikováno v:
Environment International, Vol 166, Iss , Pp 107366- (2022)
The health effects of exposure to secondary organic aerosols (SOAs) are still limited. Here, we investigated and compared the toxicities of soot particles (SP) coated with β-pinene SOA (SOAβPin-SP) and SP coated with naphthalene SOA (SOANap-SP) in
Externí odkaz:
https://doaj.org/article/bd48c19d14b74b3a80d1bdf5c378cd84
Autor:
Yue Hu, Ghalia Rehawi, Lambert Moyon, Nathalie Gerstner, Christoph Ogris, Janine Knauer-Arloth, Florian Bittner, Annalisa Marsico, Nikola S. Mueller
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
COVID-19 is a heterogeneous disease caused by SARS-CoV-2. Aside from infections of the lungs, the disease can spread throughout the body and damage many other tissues, leading to multiorgan failure in severe cases. The highly variable symptom severit
Externí odkaz:
https://doaj.org/article/61cf86274b1a4c7a937948675af97a9b
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Constantly decreasing costs of high-throughput profiling on many molecular levels generate vast amounts of multi-omics data. Studying one biomedical question on two or more omic levels provides deeper insights into underlying molecular proce
Externí odkaz:
https://doaj.org/article/4ae008adfebe443dacd926946dbcc490
Autor:
Emelie Berglund, Jonas Maaskola, Niklas Schultz, Stefanie Friedrich, Maja Marklund, Joseph Bergenstråhle, Firas Tarish, Anna Tanoglidi, Sanja Vickovic, Ludvig Larsson, Fredrik Salmén, Christoph Ogris, Karolina Wallenborg, Jens Lagergren, Patrik Ståhl, Erik Sonnhammer, Thomas Helleday, Joakim Lundeberg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Heterogeneity within tumors presents a challenge to cancer treatment. Here, the authors investigate transcriptional heterogeneity in prostate cancer, examining expression profiles of different tissue components and highlighting expression gradients i
Externí odkaz:
https://doaj.org/article/df809a2fbbdf48cfa7dfe5406664fb32
Autor:
Mohammad Asim, Firas Tarish, Heather I. Zecchini, Kumar Sanjiv, Eleni Gelali, Charles E. Massie, Ajoeb Baridi, Anne Y. Warren, Wanfeng Zhao, Christoph Ogris, Leigh-Anne McDuffus, Patrice Mascalchi, Greg Shaw, Harveer Dev, Karan Wadhwa, Paul Wijnhoven, Josep V. Forment, Scott R. Lyons, Andy G. Lynch, Cormac O’Neill, Vincent R. Zecchini, Paul S. Rennie, Aria Baniahmad, Simon Tavaré, Ian G. Mills, Yaron Galanty, Nicola Crosetto, Niklas Schultz, David Neal, Thomas Helleday
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Tumours with homologous recombination (HR) defects become sensitive to PARPi. Here, the authors show that androgen receptor (AR) regulates HR and AR inhibition activates the PARP pathway in vivo, thus inhibition of both AR and PARP is required for ef
Externí odkaz:
https://doaj.org/article/6dd1f31e993c4c649fd8af898835fe41
Autor:
Nathalie Acevedo, Giovanni Scala, Simon Kebede Merid, Paolo Frumento, Sören Bruhn, Anna Andersson, Christoph Ogris, Matteo Bottai, Göran Pershagen, Gerard H. Koppelman, Erik Melén, Erik Sonnhammer, Johan Alm, Cilla Söderhäll, Juha Kere, Dario Greco, Annika Scheynius
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 801 (2021)
DNA methylation changes may predispose becoming IgE-sensitized to allergens. We analyzed whether DNA methylation in peripheral blood mononuclear cells (PBMC) is associated with IgE sensitization at 5 years of age (5Y). DNA methylation was measured in
Externí odkaz:
https://doaj.org/article/11251bee32ec4ec491fe5b0bbb672c15
Autor:
Anna M Lipp, Kata Juhasz, Christian Paar, Christoph Ogris, Paul Eckerstorfer, Roland Thuenauer, Jan Hesse, Benedikt Nimmervoll, Hannes Stockinger, Gerhard J Schütz, Ulrich Bodenhofer, Zsolt Balogi, Alois Sonnleitner
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85934 (2014)
The glycosylphosphatidylinositol (GPI)-anchored molecule CD59 has been implicated in the modulation of T cell responses, but the underlying molecular mechanism of CD59 influencing T cell signaling remained unclear. Here we analyzed Jurkat T cells sti
Externí odkaz:
https://doaj.org/article/cc5d1e13630c4fe8bfaff49e64bdd8ac
Autor:
Catherine Delbrouck, Nicole Kiweler, Vitaly I. Pozdeev, Laura Neises, Anaïs Oudin, Anne Schuster, Aymeric Fouquier d’Hérouël, Ruolin Shen, Rashi Halder, Antoine Lesur, Christoph Ogris, Nadia I. Lorenz, Christian Jaeger, Michael W. Ronellenfitsch, Marie Piraud, Alexander Skupin, Simone P. Niclou, Elisabeth Letellier, Johannes Meiser
Metabolic rewiring is essential to enable cancer onset and progression. One important metabolic pathway that is often hijacked by cancer cells is the one-carbon cycle, in which the third carbon of serine is oxidized to formate. We have previously sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecb9b1c6f36440a0d52dd55e5d9e89de
https://doi.org/10.1101/2023.01.23.525172
https://doi.org/10.1101/2023.01.23.525172
Repeated toxic injuries of murine liver are tolerated through minute steatosis and mild inflammation
Autor:
Seddik Hammad, Christoph Ogris, Amnah Othman, Pia Erdoesi, Wolfgang Schmidt-Heck, Ina Biermayer, Barbara Helm, Yan Gao, Weronika Piorońska, Lorenza D'Alessandro, Fabian J. Theis, Matthias P. Ebert, Ursula Klingmüller, Jan Hengstler, Nikola S. Mueller, Steven Dooley
Publikováno v:
39. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ad77dd1aef2561cdf062da62650192b
https://doi.org/10.1055/s-0042-1759925
https://doi.org/10.1055/s-0042-1759925